M. Flossdorf

发表

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

B. Kuster, D. Saur, M. Schmidt-Supprian, 2021, Nature Cancer.

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection

V. Buchholz, D. Busch, T. Höfer, 2020, Nature Immunology.

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

Na Li, Andreas Thiel, Andreas Bosio, 2010, Nature Immunology.

Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

Thomas Höfer, Hansjörg Hauser, Melanie Rinas, 2012, Molecular systems biology.

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

Tim Holland-Letz, Thomas Höfer, Michael Reth, 2015, Nature.

Disparate Individual Fates Compose Robust CD8+ T Cell Immunity

Thomas Höfer, Matthias Schiemann, Veit R. Buchholz, 2013, Science.

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells.

Christian Stemberger, V. Buchholz, D. Busch, 2014, Immunity.

Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

N. Halama, A. Trumpp, M. Büchler, 2016, Oncoimmunology.

Single-Cell Resolution of T Cell Immune Responses.

V. Buchholz, Michael Flossdorf, M. Flossdorf, 2018, Advances in immunology.

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments

Dorothea Busse, A. Scheffold, T. Höfer, 2010, Proceedings of the National Academy of Sciences.

Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling.

R. Rad, M. Colomé-Tatché, M. Schmidt-Supprian, 2021, Immunity.

MicroRNA-182 is induced by IL-2 and promotes clonal expansion of 1 activated helper T lymphocytes 2

Thomas, Christoph, Wei, 2019 .

CD8+ T cell diversification by asymmetric cell division

Thomas Höfer, D. Busch, T. Höfer, 2015, Nature Immunology.

Heritable changes in division speed accompany the diversification of single T cell fate

D. Busch, T. Schroeder, A. Kazeroonian, 2021, bioRxiv.

Individual T helper cells have a quantitative cytokine memory.

Yevhen Vainshtein, Thomas Höfer, Stefan H. Kaufmann, 2015, Immunity.

Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

D. Busch, T. Höfer, Joseph C. Sun, 2021, Immunity.

Stem-cell dynamics and lineage topology from in vivo fate mapping in the hematopoietic system.

Thomas Höfer, T. Höfer, Melania Barile, 2016, Current opinion in biotechnology.

The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones

R. Offringa, J. Haanen, R. Kiessling, 2020, Clinical Cancer Research.

Next‐generation TCR sequencing – a tool to understand T‐cell infiltration in human cancers

R. Offringa, Michael Flossdorf, I. Poschke, 2016, The Journal of pathology.

Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2’-O-Methylation Mutant

K. Rohr, N. Harder, R. Bartenschlager, 2015, PLoS pathogens.

Hypercharge-Universal Topcolor

R. Chivukula, E. Simmons, S. Chiara, 2007, 0711.1127.

Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection.

Jennifer D. Oduro, L. Čičin-Šain, M. Schiemann, 2019, Immunity.

Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response.

Michael Flossdorf, M. Gerhard, A. Toska, 2019, Cell reports.

Antihypertensive drugs in COVID-19 infection

H. Schunkert, Y. Pinto, M. Beudel, 2020, European heart journal. Cardiovascular pharmacotherapy.

The CMV-Specific CD8+ T Cell Response Is Dominated by Supra-Public Clonotypes with High Generation Probabilities

D. Busch, Michael Flossdorf, K. Schober, 2020, Pathogens.

Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells

T. Höfer, M. Löhning, A. Hegazy, 2022, Frontiers in Immunology.

High-resolution kinetic gene expression analysis of T helper cell differentiation reveals a STAT-dependent, unique transcriptional program in Th1/2 hybrid cells

T. Höfer, M. Löhning, A. Hegazy, 2022, bioRxiv.

TCR Signal Quality Modulates Fate Decisions of Single CD4+ T Cells in a Probabilistic Manner.

D. Busch, T. Höfer, L. Kretschmer, 2017, Cell reports.

Differential expansion of T central memory precursor and effector subsets is regulated by division speed

D. Busch, S. Heinzel, Irina Treise, 2020, Nature Communications.