S. A. Kang

发表

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

D. Sabatini, N. Gray, W. M. Kuehl, 2009, Cell.

Native capillary isoelectric focusing for the separation of protein complex isoforms and subcomplexes.

J. Yates, D. Sabatini, T. Davis, 2010, Analytical chemistry.

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

Gordon B Mills, David M Sabatini, G. Mills, 2016, Cancer research.

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

D. Sabatini, M. Yaffe, N. Gray, 2013, Science.

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

Anne E Carpenter, Katherine L. Madden, D. Guertin, 2011, Cell.

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

S. Elledge, D. Sabatini, M. Niepel, 2013, Cancer research.

Characterization of Torin 2 , an ATP-Competitive Inhibitor of mTOR , ATM , and ATR Citation

S. Elledge, D. Sabatini, M. Niepel, 2013 .

ATM , and ATR Characterization of Torin 2 , an ATP-Competitive Inhibitor of mTOR

S. Elledge, D. Sabatini, M. Niepel, 2013 .

mTOR , ATM and ATR Characterization of Torin 2 , an ATP-competitive inhibitor of

S. Elledge, D. Sabatini, M. Niepel, 2013 .

Therapeutics , Targets , and Chemical Biology Characterization of Torin 2 , an ATP-Competitive Inhibitor of mTOR , ATM , and ATR

S. Elledge, D. Sabatini, M. Niepel, 2013 .

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1*

D. Sabatini, N. Gray, Qingsong Liu, 2009, Journal of Biological Chemistry.

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

S. Carr, Robert A Lindquist, D. Sabatini, 2007, Molecular cell.

Development of ATP-competitive mTOR inhibitors.

D. Sabatini, N. Gray, Qingsong Liu, 2012, Methods in molecular biology.

Mammalian Target of Rapamycin ( mTOR ) Inhibitor for Treatment of Cancer

D. Sabatini, N. Gray, Qingsong Liu, 2011 .

Discovery of 9-(6-aminopyridin-3-yl)-1-(3- (trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective and orally available mTOR inhibitor for treatment of cancer

D. Sabatini, N. Gray, Qingsong Liu, 2011 .

Structure of the human mTOR complex I and its implications for rapamycin inhibition.

D. Sabatini, T. Walz, C. Yip, 2010, Molecular cell.

Discovery of 1-( 4-( 4-Propionylpiperazin-1-yl )-3-( trifluoromethyl ) phenyl )-9-( quinolin-3-yl ) benzo [ h ] [ 1 , 6 ] naphthyridin-2 ( 1 H )-one as a Highly Potent

N. Gray, Qingsong Liu, W. Hur, 2014 .

Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer.

D. Sabatini, N. Gray, Qingsong Liu, 2010, Journal of medicinal chemistry.

A small molecule inhibitor of Rheb selectively targets mTORC1 signaling

S. J. Mahoney, E. Saiah, G. Vlasuk, 2018, Nature Communications.

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

D. Sabatini, M. Yaffe, N. Gray, 2011, Science.

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

S. Gygi, D. Sabatini, Noah Dephoure, 2019, Proceedings of the National Academy of Sciences.

mTORC1 activates PASK-Wdr5 signaling to epigenetically connect the nutrient status with myogenesis

S. Gygi, D. Sabatini, Noah Dephoure, 2017, bioRxiv.

A small molecule inhibitor of Rheb selectively targets mTORC1 signaling

S. J. Mahoney, E. Saiah, G. Vlasuk, 2018, Nature Communications.

Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics*

P. Sorger, D. Sabatini, A. Look, 2012, The Journal of Biological Chemistry.

Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability.

D. Sabatini, N. Gray, Qingsong Liu, 2011, Bioorganic & medicinal chemistry letters.

Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.

Shomit Sengupta, S. J. Mahoney, E. Saiah, 2019, Cell chemical biology.

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

S. Elledge, D. Sabatini, M. Yaffe, 2011, Science.

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1*

D. Sabatini, N. Gray, Qingsong Liu, 2009, Journal of Biological Chemistry.

Kang Starvation and Rapamycin mTORC 1 Phosphorylation Sites Encode Their Sensitivity to

Michael B. Yaffe, David M. Sabatini, Benjamin E. Turk, 2013 .