J. Ridinger

发表

First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement

Aubry K. Miller, Raphael R. Steimbach, W. Sippl, 2022, Chembiochem : a European journal of chemical biology.

L1CAM

P. Altevogt, Uwe Schirmer, S. Bondong, 2012, Cell adhesion & migration.

Body fluid derived exosomes as a novel template for clinical diagnostics

P. Altevogt, S. Keller, Anne-kathleen Rupp, 2011, Journal of Translational Medicine.

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

David T. W. Jones, S. Pfister, T. Hielscher, 2016, Oncotarget.

Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

Karen S. Frese, S. Vega-Rubín-de-Celis, O. Witt, 2021, Cells.

Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation.

J. Utikal, P. Altevogt, V. Umansky, 2014, Seminars in cancer biology.

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

David T. W. Jones, M. Kool, S. Pfister, 2018, Clinical Cancer Research.

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

Aubry K. Miller, O. Witt, A. Hamacher-Brady, 2018, Scientific Reports.

ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein

David C. Jones, O. Witt, M. Michaelis, 2022, Molecular oncology.

Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma

David T. W. Jones, Karen S. Frese, F. Westermann, 2021, Cancers.

First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Inhibitors of Neuroblastoma Cell Colony Growth That Increase Lysosome Accumulation

Aubry K. Miller, W. Sippl, D. Christianson, 2020 .

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.

Aubry K. Miller, Raphael R. Steimbach, Magalie N. E. Géraldy, 2018, Journal of medicinal chemistry.

Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance

A. Schober, O. Witt, M. Sill, 2017, Cell Death & Disease.

Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.

W. Sippl, C. Romier, D. Christianson, 2022, European journal of medicinal chemistry.

Identification of HDAC10 Inhibitors that Modulate Autophagy-Related Proteins in Transformed Cells

W. Sippl, C. Romier, D. Christianson, 2022 .

Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.

Aubry K. Miller, Raphael R. Steimbach, Magalie N. E. Géraldy, 2021, Journal of the American Chemical Society.

Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts

F. Westermann, O. Witt, B. Meder, 2020, Pharmaceuticals.

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors

Aubry K. Miller, Raphael R. Steimbach, Magalie N. E. Géraldy, 2020, ChemMedChem.

The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines

Aubry K. Miller, F. Westermann, O. Witt, 2018, Archives of Toxicology.

Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models

Karen S. Frese, David C. Jones, F. Westermann, 2022, Cancers.

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

W. Sippl, C. Romier, M. Jung, 2022, International journal of molecular sciences.

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling*

P. Altevogt, F. Marmé, L. Umansky, 2013, The Journal of Biological Chemistry.

, Johannes Ridinger , via Toll-like Receptor Signaling CellsInflammatory Cytokines in Monocytic Body Fluid Exosomes Promote Secretion of Signal Transduction

P. Altevogt, F. Marmé, L. Umansky, 2013 .

Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells

David C. Jones, M. Roussel, M. Kool, 2023, Journal of Neuro-Oncology.

Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.

F. Westermann, M. Kool, N. Jäger, 2020, Neuro-oncology.

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

Aubry K. Miller, O. Witt, A. Hamacher-Brady, 2018, Scientific Reports.

The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines

Aubry K. Miller, F. Westermann, O. Witt, 2018, Archives of Toxicology.

Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells

T. Hielscher, T. Milde, I. Oehme, 2023, Journal of Neuro-Oncology.

Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.

Aubry K. Miller, Raphael R. Steimbach, G. Médard, 2022, Journal of the American Chemical Society.