Panos Macheras

发表

Panos Macheras, Athanassios Iliadis, P. Macheras, 2016 .

Dynamical Aspects of Pharmacokinetic/Pharmacodynamic & Quantitative Systems Pharmacology Models

Panos Macheras, Panteleimon D. Mavroudis, Ioannis Loisios-Konstantinidis, 2020 .

The Changing Face of the Rate Concept in Biopharmaceutical Sciences: From Classical to Fractal and Finally to Fractional

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2011, Pharmaceutical Research.

A Comment on “Adverse Drug Reactions and Avalanches: Life at the Edge of Chaos”

Panos Macheras, Aristides Dokoumetzidis, 2006, Journal of clinical pharmacology.

Nonlinear Dynamics and Chaos Theory: Concepts and Applications Relevant to Pharmacodynamics

Panos Macheras, Athanassios Iliadis, Aristides Dokoumetzidis, 2001, Pharmaceutical Research.

An Insight into the Properties of a Two-Stage Design in Bioequivalence Studies

Panos Macheras, Vangelis Karalis, 2013, Pharmaceutical Research.

Modeling and administration scheduling of fractional-order pharmacokinetic systems

Aris Dokoumetzidis, Pantelis Sopasakis, Panagiotis Patrinos, 2017, 1701.08668.

In silico prediction of ADME and pharmacokinetics. Report of an expert meeting organised by COST B15.

Panos Macheras, Alan R. Boobis, Pierre Kremers, 2002, European Journal of Pharmaceutical Sciences.

The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines.

Panos Macheras, Christel A. S. Bergström, Aggelos Charalabidis, 2019, International journal of pharmaceutics.

On the ubiquitous presence of fractals and fractal concepts in pharmaceutical sciences: a review.

Natassa Pippa, Costas Demetzos, Panos Macheras, 2013, International journal of pharmaceutics.

A century of dissolution research: from Noyes and Whitney to the biopharmaceutics classification system.

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2006, International journal of pharmaceutics.

A Model for Transport and Dispersion in the Circulatory System Based on the Vascular Fractal Tree

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2003, Annals of Biomedical Engineering.

Heterogeneous Tube Model for the Study of Small Intestinal Transit Flow

Panos Macheras, Alkiviadis Kalampokis, Panos Argyrakis, 2004, Pharmaceutical Research.

The heterogeneous course of drug transit through the body.

Panos Macheras, Athanassios Iliadis, Aristides Dokoumetzidis, 2004, Trends in pharmacological sciences.

Nonlinear dynamics in clinical pharmacology: the paradigm of cortisol secretion and suppression.

Panos Macheras, Athanassios Iliadis, Aristides Dokoumetzidis, 2002, British journal of clinical pharmacology.

A Heterogeneous Tube Model of Intestinal Drug Absorption Based on Probabilistic Concepts

Panos Macheras, Alkiviadis Kalampokis, Panos Argyrakis, 1999, Pharmaceutical Research.

Identification of Biowaivers Among Class II Drugs: Theoretical Justification and Practical Examples

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2004, Pharmaceutical Research.

Power law IVIVC: an application of fractional kinetics for drug release and absorption.

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Fractional calculus in pharmacokinetics

Pantelis Sopasakis, Haralambos Sarimveis, Panos Macheras, 2018, Journal of Pharmacokinetics and Pharmacodynamics.

Fractional kinetics in multi-compartmental systems

Richard Magin, Panos Macheras, Aristides Dokoumetzidis, 2010, Journal of Pharmacokinetics and Pharmacodynamics.

Novel Scaled Average Bioequivalence Limits Based on GMR and Variability Considerations

Panos Macheras, Vangelis Karalis, Mira Symillides, 2004, Pharmaceutical Research.

Current regulatory approaches of bioequivalence testing

Panos Macheras, Vangelis Karalis, V. Karalis, 2012, Expert opinion on drug metabolism & toxicology.

A Report from the Pediatric Formulations Task Force: Perspectives on the State of Child-Friendly Oral Dosage Forms

Panos Macheras, Georgia Charkoftaki, Jörg Breitkreutz, 2013, The AAPS Journal.

A Population Growth Model of Dissolution

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 1997, Pharmaceutical Research.

Fractal kinetics in drug release from finite fractal matrices

Panos Macheras, Panos Argyrakis, Kosmas Kosmidis, 2003 .

A Physiologically Based Approach for the Estimation of Recirculatory Parameters

Panos Macheras, Aristides Dokoumetzidis, Vangelis Karalis, 2004, Journal of Pharmacology and Experimental Therapeutics.

Michaelis-Menten kinetics under spatially constrained conditions: application to mibefradil pharmacokinetics.

Panos Macheras, Panos Argyrakis, Kosmas Kosmidis, 2004, Biophysical journal.

Modeling and Monte Carlo simulations in oral drug absorption.

Panos Macheras, Panos Argyrakis, Aristides Dokoumetzidis, 2005, Basic & clinical pharmacology & toxicology.

Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches

Panos Macheras, Athanassios Iliadis, P. Macheras, 2005 .

Multivariate Statistics of Disposition Pharmacokinetic Parameters for Structurally Unrelated Drugs Used in Therapeutics

Panos Macheras, Anna Tsantili-Kakoulidou, Vangelis Karalis, 2002, Pharmaceutical Research.

On the Heterogeneity of Drug Dissolution and Release

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2000, Pharmaceutical Research.

A Stochastic Model Describes the Heterogeneous Pharmacokinetics of Cyclosporin

Panos Macheras, Athanassios Iliadis, Laurent Claret, 2001, Journal of Pharmacokinetics and Pharmacodynamics.

A Reappraisal of Drug Release Laws Using Monte Carlo Simulations: The Prevalence of the Weibull Function

Panos Macheras, Panos Argyrakis, Kosmas Kosmidis, 2003, Pharmaceutical Research.

Fractional kinetics in drug absorption and disposition processes

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2009, Journal of Pharmacokinetics and Pharmacodynamics.

Quantitative Biopharmaceutics Classification System: The Central Role of Dose/Solubility Ratio

Panos Macheras, P. Macheras, E. Rinaki, 2003, Pharmaceutical Research.

Drug Disposition Viewed in Terms of the Fractal Volume of Distribution

Panos Macheras, Vangelis Karalis, V. Karalis, 2002, Pharmaceutical Research.

A Fractal Approach to Heterogeneous Drug Distribution: Calcium Pharmacokinetics

Panos Macheras, P. Macheras, 1996, Pharmaceutical Research.

Bioequivalence of Highly Variable Drugs: A Comparison of the Newly Proposed Regulatory Approaches by FDA and EMA

Panos Macheras, Vangelis Karalis, Mira Symillides, 2011, Pharmaceutical Research.

Fractal Volume of Drug Distribution: It Scales Proportionally to Body Mass

Panos Macheras, Athanassios Iliadis, Vangelis Karalis, 2001, Pharmaceutical Research.

The Mean Dissolution Time Depends on the Dose/Solubility Ratio

Panos Macheras, Aristides Dokoumetzidis, A. Dokoumetzidis, 2003, Pharmaceutical Research.

Physiologically-Based PK/PD Modelling of Therapeutic Macromolecules

Panos Macheras, A. Peer, P. Macheras, 2009, Pharmaceutical Research.

Carrier-Mediated Transport Can Obey Fractal Kinetics

Panos Macheras, P. Macheras, 1995, Pharmaceutical Research.

A commentary on fractionalization of multi-compartmental models

Richard Magin, Panos Macheras, Aristides Dokoumetzidis, 2010, Journal of Pharmacokinetics and Pharmacodynamics.

Pharmacodynamic considerations in bioequivalence assessment: comparison of novel and existing metrics.

Panos Macheras, Vangelis Karalis, V. Karalis, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Analysis of Case II drug transport with radial and axial release from cylinders.

Panos Macheras, Panos Argyrakis, Kosmas Kosmidis, 2003, International journal of pharmaceutics.

Gastrointestinal Drug Absorption: Is It Time to Consider Heterogeneity as Well as Homogeneity?

Panos Macheras, Panos Argyrakis, P. Argyrakis, 1997, Pharmaceutical Research.