David G. Johnson

发表

The p53 R72P polymorphism does not affect the physiological response to ionizing radiation in a mouse model

D. Kusewitt, K. Lin, F. Benavides, 2017, Cell cycle.

The RB-E2F1 pathway regulates autophagy.

T. McDonnell, N. Shinojima, J. Xu, 2010, Cancer research.

Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues

C. Conti, H. Kiyokawa, P. Sicinski, 2004, Molecular and Cellular Biology.

Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.

K. Aldape, W. Yung, G. Fuller, 2007, Cancer research.

Chromatin: Receiver and Quarterback for Cellular Signals

Sharon Y. R. Dent, David G. Johnson, 2013, Cell.

Repression of Androgen Receptor Transcription through the E2F1/DNMT1 Axis

M. Day, T. R. Berton, C. D. Valdez, 2011, PloS one.

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis.

David G Johnson, J. DeGregori, James DeGregori, 2006, Current molecular medicine.

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc

John T. Powers, M. McArthur, Sungki Hong, 2006, Proceedings of the National Academy of Sciences of the United States of America.

The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts

R. Vélez-Cruz, David G. Johnson, 2017, International journal of molecular sciences.

Myc lacks E2F1's ability to suppress skin carcinogenesis

C. Conti, R. Schneider-Broussard, R. Rounbehler, 2001, Oncogene.

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

J. Nevins, W. D. Cress, David G Johnson, 1993, Nature.

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

J. Blando, C. Conti, A. Senderowicz, 2009, Molecular carcinogenesis.

ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc

John T. Powers, C. Conti, David G Johnson, 2002, Molecular and Cellular Biology.

Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context.

David G Johnson, J. DeGregori, James Degregori, 2006, Current molecular medicine.

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1

S. Li, M. Hung, R. Ezhilarasan, 2016, Science Advances.

Gene expression alterations during HGF-induced dedifferentiation of a renal tubular epithelial cell line (MDCK) using a novel canine DNA microarray.

J. Tobias, J. Lipschutz, David G Johnson, 2004, American journal of physiology. Renal physiology.

Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin

C. Conti, I. Gimenez-Conti, M. Lacava, 1998, Oncogene.

Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.

Jing Xu, Satoru Kyo, Hong Jiang, 2005, Journal of the National Cancer Institute.

xpression of Transcription Factor E 2 F 1 and Telomerase in Glioblastomas : Mechanistic Linkage and Prognostic Signi fi cance

McDonald, K. Aldape, J. Shay, 2005 .

Conditional transformation of rat embryo fibroblast cells by a cyclin D1-cdk4 fusion gene

S. A. Watkins, K. Houck, N. Stamm, 1999, Oncogene.

E2F4 and E2F1 Have Similar Proliferative Properties but Different Apoptotic and Oncogenic Properties In Vivo

David G Johnson, Dawei Wang, J. Russell, 2000, Molecular and Cellular Biology.

E2F1 Has Both Oncogenic and Tumor-Suppressive Properties in a Transgenic Model

C. Conti, David G Johnson, J. Russell, 1999, Molecular and Cellular Biology.

Transgenic Model Tumor-Suppressive Properties in a E 2 F 1 Has Both Oncogenic and

C. Conti, David G Johnson, J. Russell, 1999 .

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

John T. Powers, E. Knudsen, C. Mayhew, 2004, Molecular cancer research : MCR.

Uses the ATM Signaling Pathway to Induce p 53 and Chk 2 Phosphorylation and Apoptosis

John T. Powers, E. Knudsen, C. Mayhew, 2004 .

A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

Arnold J Levine, Vinod Pant, Guillermina Lozano, 2010, Cancer cell.

IN CELL CYCLE CONTROL AND CANCER

David G Johnson, R. Schneider-Broussard, David G. Johnson, 1998 .

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice

Hongyu Zhao, D. Brash, T. R. Berton, 2003, Nature Cell Biology.

Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck

Q. Wei, Zhensheng Liu, E. Sturgis, 2011, Molecular carcinogenesis.

Regulation of BRCA1 Expression by the Rb-E2F Pathway*

M. Macleod, Addanki P. Kumar, Aijin Wang, 2000, The Journal of Biological Chemistry.

TIE 2-mediated tyrosine phosphorylation of H 4 regulates DNA damage response by recruiting ABL 1

S. Li, M. Hung, R. Ezhilarasan, 2016 .

Advances in Brief E 2 F-1 Gene Transfer Enhances Invasiveness of Human Head and Neck Carcinoma Cell Lines 1

A. Klein-Szanto, David G Johnson, S. Liu, 2000 .

Mouse models for the p53 R72P polymorphism mimic human phenotypes.

M. McArthur, R. Kuiper, T. R. Berton, 2010, Cancer research.

Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation

T. R. Berton, D. Mitchell, David G Johnson, 2005, Oncogene.

Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.

S. Tucker, A. Multani, Sandy Chang, 2007, Cancer research.

Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.

C. Conti, David G Johnson, R. Rounbehler, 2002, Cancer research.

E2F1 and E2F3 activate ATM through distinct mechanisms to promote E1A-induced apoptosis

Sungki Hong, Q. Paulson, David G. Johnson, 2008, Cell cycle.

E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

B. Liu, T. Kutateladze, M. Bedford, 2019, Nature Communications.

E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.

D. Mitchell, David G Johnson, A. K. Biswas, 2014, Cancer research.

Oncogenes and the DNA Damage Response: Myc and E2F1 Engage the ATM Signaling Pathway to Activate p53 and Induce Apoptosis

John T. Powers, Sungki Hong, R. Pusapati, 2006, Cell cycle.

GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage

Jie Chen, D. Mitchell, David G Johnson, 2010, Nucleic acids research.

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway

Lei Li, Xin Wang, Ying-jun Jiang, 2010, Proceedings of the National Academy of Sciences.

Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.

Q. Wei, Zhensheng Liu, X. Guan, 2014, Biochemical and biophysical research communications.

GCN 5 and E 2 F 1 stimulate nucleotide excision repair by promoting H 3 K 9 acetylation at sites of damage

Jie Chen, D. Mitchell, David G Johnson, 2011 .

E2F1 Localizes to Sites of UV-induced DNA Damage to Enhance Nucleotide Excision Repair*

Jie Chen, T. R. Berton, D. Mitchell, 2010, The Journal of Biological Chemistry.

Modeling gene–environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility

D. Kusewitt, Guojun Li, Donna F. Kusewitt, 2014, Molecular carcinogenesis.

Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage.

David G Johnson, A. K. Biswas, Anup K Biswas, 2012, Cancer research.

E2F1 and p53 Transcription Factors as Accessory Factors for Nucleotide Excision Repair

R. Vélez-Cruz, David G. Johnson, 2012, International journal of molecular sciences.

The E2F1 transcription factor and RB tumor suppressor moonlight as DNA repair factors

Jie Chen, Ruifeng Guo, A. K. Biswas, 2020, Cell cycle.

Deregulated expression of DP1 induces epidermal proliferation and enhances skin carcinogenesis

D. Johnson, Dawei Wang, J. Russell, 2001, Molecular carcinogenesis.

Differential activities of E2F family members: Unique functions in regulating transcription

David G Johnson, A. Pierce, R. Schneider-Broussard, 1998, Molecular carcinogenesis.

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

C. Conti, David G Johnson, A. Pierce, 1998, Oncogene.

Effects of P190b Over-Expression on Mammary Epithelial Cell Morphology and Behavior

David G. Johnson, 2008 .

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1

David G Johnson, A. K. Biswas, F. Cole, 2016, Genes & development.

Transcription of Immunoglobulin Genes

J. D. Capra, David G Johnson, L. Carayannopoulos, 2022 .

Direct Regulation of DNA Repair by E2F and RB in Mammals and Plants: Core Function or Convergent Evolution?

David G Johnson, B. Dennehey, Swarnalatha Manickavinayaham, 2021, Cancers.

E2F2 suppresses Myc‐induced proliferation and tumorigenesis

M. McArthur, David G Johnson, R. Rounbehler, 2010, Molecular carcinogenesis.

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck

Q. Wei, Zhensheng Liu, E. Sturgis, 2012, Molecular carcinogenesis.

E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks

Jie Chen, Ruifeng Guo, F. Zhu, 2011, Cell cycle.

Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues

C. Deng, J. Jorcano, C. Conti, 2003, Oncogene.

Cancer esearch cular and Cellular Pathobiology R RBE 2 F 1 Pathway Regulates Autophagy

T. McDonnell, N. Shinojima, J. Fueyo, 2010 .

Cancer esearch cular and Cellular Pathobiology R RBE 2 F 1 Pathway Regulates Autophagy

T. McDonnell, N. Shinojima, J. Fueyo, 2010 .

SAGE profiling of UV‐induced mouse skin squamous cell carcinomas, comparison with acute UV irradiation effects

J. Rundhaug, T. R. Berton, A. Pavone, 2005, Molecular carcinogenesis.

The paradox of E2F1: Oncogene and tumor suppressor gene

D. Johnson, David G Johnson, David G. Johnson, 2000, Molecular carcinogenesis.

Cyclins and cell cycle checkpoints.

D. Johnson, C. Walker, C. L. Walker, 1999, Annual review of pharmacology and toxicology.

Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes

V. Pant, G. Lozano, S. Xiong, 2018, Oncogene.

Oncogenic capacity of the E2F1 gene.

J. Nevins, W. D. Cress, D. Johnson, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

D. Johnson, C. Conti, A. Pierce, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

J. Nevins, D. Johnson, K. Ohtani, 1994, Genes & development.

Regulation of E2F-1 gene expression by p130 (Rb2) and D-type cyclin kinase activity.

D. Johnson, David G. Johnson, 1995, Oncogene.

Slug Expression in Mouse Skin and Skin Tumors Is Not Regulated by p53

D. Kusewitt, T. Oberyszyn, J. Rundhaug, 2013, The Journal of investigative dermatology.

E2F3a Stimulates Proliferation, p53-Independent Apoptosis and Carcinogenesis in a Transgenic Mouse Model

M. McArthur, David G Johnson, Q. Paulson, 2006, Cell cycle.

Molecular and Cellular Pathobiology Cancer Research Mouse Models for the p 53 R 72 P Polymorphism Mimic Human Phenotypes

M. McArthur, A. D. Vries, R. Kuiper, 2010 .

Increased E 2 F 1 activity induces skin tumors in mice heterozygous and nullizygous for p 53

C. Conti, A. Pierce, I. Gimenez-Conti, 1998 .

E 2 F 1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks

Jie Chen, David G Johnson, Ruifeng Guo, 2011 .

Role of E2F in cell cycle control and cancer.

D. Johnson, R. Schneider-Broussard, D G Johnson, 1998, Frontiers in bioscience : a journal and virtual library.

A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

A. Levine, V. Pant, T. Iwakuma, 2010, Cancer cell.