B. Lewis

发表

Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability.

Leslie Wilson, Jennifer A. Smith, M. Jordan, 2010, Biochemistry.

Process Development of Halaven®: Synthesis of the C14–C35 Fragment via Iterative Nozaki–Hiyama–Kishi Reaction–Williamson Ether Cyclization

M. Kubota, W. Christ, Yongbo Hu, 2013, Synlett.

Commercial Manufacture of Halaven®: Chemoselective Transformations En Route to Structurally Complex Macrocyclic Ketones

M. Kubota, N. Asakawa, Yongbo Hu, 2013, Synlett.

Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions.

Melvin J. Yu, M. Towle, B. Littlefield, 2011, Cancer research.

(+)-(2R, 8AR*)-(8,8-DIMETHOXYCAMPHORYL)SULFONYLOXAZIRIDINE AND (+)-(2R, 8AR*)-(8,8-DICHLOROCAMPHORYL)-SULFONYLOXAZIRIDINE : (4H-4A, 7-METHANOOXAZIRINO 3,2-I2,1BENZISOTHIAZOLE, TETRAHYDRO-8,8-DIMETHOXY-9,9-DIMETHYL-, 3,3-DIOXID E, 2R-(2ALPHA , 4AALPHA , 7ALPHA , 8AR*)- AND 4H-4A, 7-METHANOOXAZIRINO3,

Anil Kumar, P. Zhou, F. A. Davis, 1996 .

Process Development of Halaven®: Synthesis of the C1–C13 Fragment from d-(–)-Gulono-1,4-lactone

M. Schnaderbeck, G. D. Wilkie, F. Fang, 2013, Synlett.

Novel second generation analogs of eribulin. Part I: Compounds containing a lipophilic C32 side chain overcome P-glycoprotein susceptibility.

Melvin J. Yu, Yongbo Hu, Karen Tendyke, 2011, Bioorganic & medicinal chemistry letters.

Novel second generation analogs of eribulin. Part II: Orally available and active against resistant tumors in vivo.

Melvin J. Yu, E. Schuck, Yongbo Hu, 2011, Bioorganic & medicinal chemistry letters.

Novel second generation analogs of eribulin. Part III: Blood-brain barrier permeability and in vivo activity in a brain tumor model.

Melvin J. Yu, E. Schuck, Yongbo Hu, 2011, Bioorganic & medicinal chemistry letters.

(+)‐(2R,8aR*)‐[(8,8‐Dimethoxycamphoryl)Sulfonyl]Oxaziridine and (+)‐(2R,8aR*)‐[(8,8‐Dichlorocamphoryl)Sulfonyl]Oxaziridine

Anil Kumar, P. Zhou, F. A. Davis, 2003 .

Determination of the Relative and Absolute Stereochemistry of Fostriecin (CI-920)

D. Boger, Masataka Hikota, B. M. Lewis, 1997 .