P. Doubleday

发表

Top-down characterization of endogenous protein complexes with native proteomics

Neil L Kelleher, Luca Fornelli, Luis F Schachner, 2017, Nature chemical biology.

Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3S,4S)-3-Amino-4-fluorocyclopentenecarboxylic Acid

G. M. Ferreira, N. Kelleher, R. Silverman, 2023, Molecules.

A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid.

N. Kelleher, Z. Wawrzak, R. Silverman, 2020, Journal of the American Chemical Society.

Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk

Henry Rodriguez, Ryan T Fellers, Richard D LeDuc, 2018, Proceedings of the National Academy of Sciences.

Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics*

Bryan P. Early, Joseph B. Greer, Chad R. Weisbrod, 2019, Molecular & Cellular Proteomics.

Dynamic metabolome profiling uncovers potential TOR signaling genes

U. Sauer, R. Loewith, Peter F. Doubleday, 2022, bioRxiv.

Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells

N. Kelleher, Ioanna Ntai, L. Fornelli, 2021, The FEBS journal.

Top-down proteomics: Where we are, where we are going?

Neil L. Kelleher, Luca Fornelli, Luis F. Schachner, 2017, Journal of proteomics.

Elucidating proteoform dynamics underlying the senescence associated secretory phenotype.

N. Kelleher, L. Fornelli, P. Doubleday, 2020, Journal of proteome research.

Extensive regulation of enzyme activity by phosphorylation in Escherichia coli

U. Sauer, Jimin Park, Harris H. Wang, 2021, Nature Communications.

Non-enzymatic acetylation inhibits glycolytic enzymes in Escherichia coli.

U. Sauer, Luca Maurer, P. Doubleday, 2023, Cell reports.

Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics

Peter F. Doubleday, B. Ballif, P. Doubleday, 2014, Proteomes.

Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase.

G. M. Ferreira, Wei Zhu, N. Kelleher, 2022, Journal of the American Chemical Society.

Remarkable and Unexpected Mechanism for (S)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase.

N. Kelleher, R. Silverman, Dali Liu, 2021, Journal of the American Chemical Society.

Mechanism-Based Design of 3-Amino-4-Halocyclopentenecarboxylic Acids as Inactivators of GABA Aminotransferase.

N. Kelleher, R. Silverman, Wei Zhu, 2020, ACS medicinal chemistry letters.

Spectrum of Apolipoprotein AI and Apolipoprotein AII Proteoforms and Their Associations With Indices of Cardiometabolic Health: The CARDIA Study

Richard D. LeDuc, N. Kelleher, D. Jacobs, 2021, Journal of the American Heart Association.

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa.

Masashi Narita, Ryan T Fellers, Neil L Kelleher, 2016, Journal of proteome research.

Phosphoproteomics Reveals Resveratrol-Dependent Inhibition of Akt/mTORC1/S6K1 Signaling

A. Alayev, M. Holz, B. Ballif, 2014, Journal of proteome research.

Dynamic metabolome profiling uncovers potential TOR signaling genes

U. Sauer, R. Loewith, Peter F. Doubleday, 2022, bioRxiv.

Mechanism of Inactivation of Ornithine Aminotransferase by (1 S,3 S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid.

N. Kelleher, R. Silverman, Dali Liu, 2019, Journal of the American Chemical Society.