T. Baker

发表

FRI0162 Investigation into the binding affinity of certolizumab pegol to fcrn and functional consequences for fcrn-mediated transcytosis: comparison to infliximab, adalimumab and etanercept

T. Baker, L. Kevorkian, A. Nesbitt, 2013 .

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation

A. Lawson, Terry S Baker, P. Miossec, 2017, Annals of the rheumatic diseases.

Certolizumab pegol does not bind the neonatal Fc receptor (FcRn): Consequences for FcRn-mediated in vitro transcytosis and ex vivo human placental transfer.

Terry S Baker, A. Nesbitt, L. Kevorkian, 2016, Journal of reproductive immunology.

Engineering synucleinopathy‐resistant human dopaminergic neurons by CRISPR‐mediated deletion of the SNCA gene

Nicola J. Drummond, T. Kunath, S. Rosser, 2018, The European journal of neuroscience.

Length-independent structural similarities enrich the antibody CDR canonical class model

C. Deane, Jiye Shi, S. Kelm, 2016, mAbs.

Analysis of heavy and light chain sequences of conventional camelid antibodies from Camelus dromedarius and Camelus bactrianus species.

Alastair D G Lawson, James Snowden, L. Griffin, 2014, Journal of immunological methods.

Improving B-cell epitope prediction and its application to global antibody-antigen docking

Jiye Shi, Charlotte M. Deane, Konrad Krawczyk, 2014, Bioinform..

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping

Jiye Shi, Richard D. Taylor, Terry Baker, 2017, Scientific Reports.

Conservation of Functional Sites on Interleukin-6 and Implications for Evolution of Signaling Complex Assembly and Therapeutic Intervention

A. Lawson, M. Carr, F. Muskett, 2012, The Journal of Biological Chemistry.

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

Alastair D G Lawson, T. Ceska, L. Griffin, 2016, mAbs.

The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection

Terry S Baker, I. S. Blagbrough, M. Eaton, 1999, FEBS letters.

Designing stapled peptides to inhibit protein‐protein interactions: An analysis of successes in a rapidly changing field

J. Michel, J. O'Connell, A. Hulme, 2020, Peptide Science.

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

A. Lawson, R. Adams, P. Vajjah, 2020, Frontiers in Immunology.

Creation of a gated antibody as a conditionally functional synthetic protein

A. Lawson, D. Anthony, B. G. Davis, 2014, Nature Communications.

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations

Richard D. Taylor, J. Essex, S. Kelm, 2022, Frontiers in Immunology.

Discovery and characterization of olokizumab

Terry Baker, Helen Neale, Tim Bourne, 2014, mAbs.

Anti-AMPA Receptor Autoantibodies Reduce Excitatory Currents in Rat Hippocampal Neurons

A. Bithell, G. Stephens, Christian Wolff, 2023, Pharmaceuticals.

B-cell epitopes: Discontinuity and conformational analysis.

Andrew C. R. Martin, Jiye Shi, S. Kelm, 2019, Molecular immunology.

Antibody i-Patch prediction of the antibody binding site improves rigid local antibody-antigen docking.

C. Deane, Jiye Shi, K. Krawczyk, 2013, Protein engineering, design & selection : PEDS.

Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR

Benjamin P. Cossins, R. Konrat, Jiye Shi, 2020, bioRxiv.

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

Terry S Baker, M. Citron, G. Mairet-Coello, 2018, Acta Neuropathologica.

Comparison of the biological properties of two anti-mucin-1 antibodies prepared for imaging and therapy

Terry S Baker, G. Pietersz, D. Wreschner, 1997, Cancer Immunology, Immunotherapy.

Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans.

A. Takada, M. Carroll, Jia Guo, 2019, Cell reports.

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling

Richard D. Taylor, David McMillan, Robert Griffin, 2017, Scientific Reports.

THE TRANSFECTION OF JURKAT T-LEUKEMIC CELLS BY USE OF PH-SENSITIVE IMMUNOLIPOSOMES

C. Catterall, B. Carrington, Malcolm N. Jones, 2002, Journal of liposome research.

Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity.

C. Wilson, T. Hupp, T. Kunath, 2018, Chemistry.

High-resolution structural information of membrane-bound α-synuclein provides insight into the MoA of the anti-Parkinson drug UCB0599

R. Konrat, Richard J. Taylor, Thomas Gossenreiter, 2023, Proceedings of the National Academy of Sciences of the United States of America.