Susan J Harvey

Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup.

R. Sridhar, D. Longhi, Christine S. Huang, 2015, Bioorganic & medicinal chemistry letters.

Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties.

K. Behnia, N. Murugesan, Z. Gu, 2013, Journal of medicinal chemistry.

Weight Loss Induced by Chronic Dapagliflozin Treatment Is Attenuated by Compensatory Hyperphagia in Diet‐Induced Obese (DIO) Rats

M. Pelleymounter, M. Cullen, Helen E. Godonis, 2012, Obesity.

Screening Hit to Clinical Candidate: Discovery of BMS-963272, a Potent, Selective MGAT2 Inhibitor for the Treatment of Metabolic Disorders.

Kimberly A. Foster, C. Chu, A. Mathur, 2021, Journal of medicinal chemistry.

DMP 504, a novel hydrogel bile acid sequestrant: II. Lipid‐lowering pharmacology in the hamster

J. Billheimer, E. Shimshick, L. C. Grimminger, 1997 .

Synthesis and Antiobesity Properties of 6-(4-Chlorophenyl)-3-(4-((3,3-difluoro-1-hydroxycyclobutyl)methoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one (BMS-814580): A Highly Efficacious Melanin Concentrating Hormone Receptor 1 (MCHR1) Inhibitor.

E. Janovitz, D. Longhi, Christine S. Huang, 2016, Journal of Medicinal Chemistry.

Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate.

J. Barrish, E. Janovitz, D. Longhi, 2014, Journal of medicinal chemistry.

Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.

S. Radhakrishnan, D. Longhi, Christine S. Huang, 2015, Bioorganic & medicinal chemistry letters.

Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders.

Lidet K. Negash, Kimberly A. Foster, A. Mathur, 2023, Journal of medicinal chemistry.