E. Blackburn

发表

Wash‐free, peptide‐based fluorogenic probes for microbial imaging

Annamaria Lilienkampf, M. Bradley, Muhammed Üçüncü, 2020, Peptide Science.

A Novel p53 Phosphorylation Site within the MDM2 Ubiquitination Signal

M. Walkinshaw, C. Verma, A. Madhumalar, 2010, The Journal of Biological Chemistry.

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.

Martin A. M. Reijns, M. Nöthen, N. Hübner, 2015, The Journal of clinical investigation.

Novel Entropically Driven Conformation-specific Interactions with Tomm34 Protein Modulate Hsp70 Protein Folding and ATPase Activities*

D. Kavan, B. Vojtesek, P. Man, 2016, Molecular & Cellular Proteomics.

Modulate Hsp70 Folding and ATPase Activities

D. Kavan, B. Vojtesek, P. Man, 2016 .

Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis.

V. Landré, M. Walkinshaw, J. Fraser, 2015, Journal of molecular biology.

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

J. Rappsilber, Christos Spanos, U. Gruneberg, 2020, Journal of Cell Science.

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

J. Rappsilber, Christos Spanos, U. Gruneberg, 2020, bioRxiv.

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

Elizabeth A. Blackburn, J. Mottram, M. Walkinshaw, 2021, Nature communications.

Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli *

B. Böttcher, M. Stevens, H. Alsarraf, 2016, The Journal of Biological Chemistry.

A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2.

M. Walkinshaw, Elizabeth A Blackburn, T. Hupp, 2014, Cellular signalling.

The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution*

Juri Rappsilber, David J. Porteous, Malcolm D. Walkinshaw, 2012, The Journal of Biological Chemistry.

The effects of phosphomimetic lid mutation on the thermostability of the N-terminal domain of MDM2.

M. Walkinshaw, Elizabeth A Blackburn, T. Hupp, 2010, Journal of molecular biology.

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor

M. Walkinshaw, T. Hupp, P. Michels, 2018, The Biochemical journal.

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation

T. Le Bihan, M. Walkinshaw, G. Loake, 2018, The Biochemical journal.

Inhibition of Antigen-Specific and Nonspecific Stimulation of Bovine T and B Cells by Lymphostatin from Attaching and Effacing Escherichia coli

M. Stevens, J. Hope, R. Cassady-Cain, 2016, Infection and Immunity.

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

David J. Porteous, Walter J. Muir, Elizabeth A. Blackburn, 2012, Human molecular genetics.

Thermo‐kinetic analysis space expansion for cyclophilin‐ligand interactions – identification of a new nonpeptide inhibitor using Biacore™ T200

M. Walkinshaw, Elizabeth A Blackburn, M. Wear, 2017, FEBS open bio.

Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90

B. Erman, V. Landré, M. Walkinshaw, 2015, Bioscience reports.

Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70- Interacting Protein (CHIP)*□S

V. Landré, M. Walkinshaw, C. Verma, 2019 .

Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)*

V. Landré, M. Walkinshaw, C. Verma, 2015, Molecular & Cellular Proteomics.

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.

D. Auld, M. Boxer, M. Walkinshaw, 2012, The Biochemical journal.

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin.

M. Walkinshaw, T. Hupp, N. Westwood, 2015 .

Estimating the affinity of protein-ligand complex from changes to the charge-state distribution of a protein in electrospray ionization mass spectrometry.

Elizabeth A. Blackburn, M. Walkinshaw, J. Maclean, 2010, Biochemical and biophysical research communications.

Targeting FKBP isoforms with small-molecule ligands.

M. Walkinshaw, E. Blackburn, 2011, Current opinion in pharmacology.

Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states.

M. Walkinshaw, Elizabeth A Blackburn, P. Michels, 2014, Biochemical and biophysical research communications.

Triazole biotin: a tight-binding biotinidase-resistant conjugate.

Elizabeth A. Blackburn, M. Wear, D. Campopiano, 2013, Organic & biomolecular chemistry.

A Streamlined, Automated Protocol for the Production of Milligram Quantities of Untagged Recombinant Rat Lactate Dehydrogenase A Using ÄKTAxpressTM

Elizabeth A Blackburn, M. Wear, I. McNae, 2015, PloS one.

Explorer A streamlined , automated protocol for the production of milligram quantities of untagged recombinant rat lactate dehydrogenase A using ÄKTAxpress

M. Wear, I. McNae, Matthew W. Nowicki, 2017 .

Chemically cross-linked hydrogels from repetitive protein arrays.

D. Hay, Rossana Boni, S. Rosser, 2023, Journal of structural biology.

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

J. Mottram, M. Walkinshaw, P. Michels, 2021, Nature Communications.

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC

Elizabeth A. Blackburn, J. Rappsilber, M. A. Abad, 2021, bioRxiv.

Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties

Mark E Tuckerman, Pei-Yang Chen, M. Tuckerman, 2018, The Journal of chemical physics.