Ching‐Ping Chen

发表

Synthesis and biological activities of 2-amino-1-arylidenamino imidazoles as orally active anticancer agents.

Chi-Hung Lin, C. Chen, Y. Chao, 2010, Journal of medicinal chemistry.

BPR0L075, a Novel Synthetic Indole Compound with Antimitotic Activity in Human Cancer Cells, Exerts Effective Antitumoral Activity in Vivo

H. Hsieh, C. Chen, Shiow-Ju Lee, 2004, Cancer Research.

Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins

C. Chen, Jen‐Shin Song, C. Shih, 2021, Journal of medicinal chemistry.

Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

Chi-Ying F. Huang, Yi-Hui Peng, H. Hsieh, 2013, Proceedings of the National Academy of Sciences.

Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.

Yi-Hui Peng, H. Hsieh, C. Chen, 2019, Journal of medicinal chemistry.

Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

Sing-Yi Wang, Mohane Selvaraj Coumar, Yu-Sheng Chao, 2010, Journal of medicinal chemistry.

Sex Differences in High‐fat Diet‐induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

C. Chen, L. Hwang, K. Liang, 2010, Obesity.

Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation

Yung Chang Hsu, C. Chen, J. Hsu, 2016, Oncotarget.

Antiangiogenic activities and cisplatin-combined antitumor activities of BPR0L075.

H. Hsieh, C. Chen, Y. Chao, 2010, Anticancer research.

Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.

H. Hsieh, C. Chen, Su-Ying Wu, 2009, Journal of medicinal chemistry.

Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas.

M. Tsou, C. Chen, Chen-Lung Huang, 2007, Journal of biomedical science.

Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91.

C. Chen, Y. Chao, Chin-Tarng Lin, 2010, Pharmacological research.

Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations.

C. Chen, Y. Chao, J. Hsu, 2015, European journal of medicinal chemistry.

Synthesis and biological evaluation of N-heterocyclic indolyl glyoxylamides as orally active anticancer agents.

Chi-Hung Lin, C. Chen, Jen‐Shin Song, 2003, Journal of medicinal chemistry.

Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type

C. Chen, Wen-Sen Lee, Y. Lai, 2009, Cancer Chemotherapy and Pharmacology.

BPR0C261 is a novel orally active antitumor agent with antimitotic and anti‐angiogenic activities

Chi-Hung Lin, C. Chen, Y. Chao, 2011, Cancer science.

BPR0C305, an orally active microtubule-disrupting anticancer agent

Chi-Hung Lin, C. Chen, Y. Chao, 2013, Anti-cancer drugs.

Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer

H. Hsieh, C. Chen, T. Lien, 2023, Journal of medicinal chemistry.

Evaluation of the Antitumor Effects of BPR1J-340, a Potent and Selective FLT3 Inhibitor, Alone or in Combination with an HDAC Inhibitor, Vorinostat, in AML Cancer

C. Chen, Y. Chao, T. Yeh, 2014, PloS one.

Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System

C. Chen, Chien Ho, Yen-Ju Chen, 2020, Scientific Reports.

Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors (GISTs) and Acute Myeloid Leukemia (AML).

Yi-Hui Peng, C. Chen, Su-Ying Wu, 2019, Journal of medicinal chemistry.

Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia.

Yi-Hui Peng, C. Chen, Su-Ying Wu, 2019 .

Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents

Chi-Hung Lin, C. Chen, T. Lien, 2012, Investigational new drugs.

Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities.

I-Lin Lu, Chien-Fu Huang, Yu-Sheng Chao, 2005, Journal of medicinal chemistry.

BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy

C. Chen, Y. Chao, T. Yeh, 2019, Translational oncology.

Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).

C. Chen, Y. Chao, J. Hsu, 2013, Bioorganic & medicinal chemistry.

Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).

C. Chen, Y. Chao, J. Hsu, 2011, Bioorganic & medicinal chemistry.

Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System

C. Chen, Chien Ho, Yen-Ju Chen, 2020, Scientific Reports.

Sex Differences in High‐fat Diet‐induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

C. Chen, L. Hwang, K. Liang, 2010, Obesity.

BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy

C. Chen, T. Yeh, Min-Hsien Wang, 2020, Translational oncology.