K. Kalesh

发表

Detectives and helpers: Natural products as resources for chemical probes and compound libraries.

Karunakaran A Kalesh, A. Parthasarathy, Pavan K. Mantravadi, 2020, Pharmacology & therapeutics.

Target identification of natural and traditional medicines with quantitative chemical proteomics approaches.

Karunakaran A Kalesh, Qingsong Lin, Hongyan Sun, 2016, Pharmacology & therapeutics.

Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana

Karunakaran A Kalesh, P. Denny, S. Cobb, 2021, mSystems.

Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action

Karunakaran A Kalesh, W. Wong, Jigang Wang, 2017, Medicinal research reviews.

The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies

Karunakaran A Kalesh, R. Dobson, A. Hudson, 2019, Antibiotics.

Small molecule probes that target Abl kinase.

Karunakaran A Kalesh, Jigang Wang, Q. Lin, 2010, Chemical communications.

Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).

Karunakaran A Kalesh, S. Yao, Liqian Gao, 2010, Chemical communications.

Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry.

Karunakaran A Kalesh, S. Yao, Kai Liu, 2009, Organic & biomolecular chemistry.

Click Chemistry as a High‐Throughput Amenable Platform in Catalomics

Karunakaran A Kalesh, Pengyu Yang, S. Yao, 2007 .

Methods of using click chemistry in the discovery of enzyme inhibitors

Karunakaran A Kalesh, S. Yao, Junqi Li, 2007, Nature Protocols.

The use of click chemistry in the emerging field of catalomics.

Karunakaran A Kalesh, S. Yao, Haibin Shi, 2010, Organic & biomolecular chemistry.

Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer.

Karunakaran A Kalesh, G. Sethi, K. Ahn, 2012, Biochemical pharmacology.

Transcriptome-Wide Identification of Coding and Noncoding RNA-Binding Proteins Defines the Comprehensive RNA Interactome of Leishmania mexicana

Karunakaran A Kalesh, J. Choudhary, Wenbin Wei, 2021, bioRxiv.

The Medicinal Chemistry of Therapeutic Peptides: Recent Developments in Synthesis and Design Optimizations.

Anutthaman Parthasarathy, Sasikala K Anandamma, Karunakaran A Kalesh, 2019, Current medicinal chemistry.

Affinity‐based proteomics reveals novel targets of inositol pyrophosphate (5‐IP7)‐dependent phosphorylation and binding in Trypanosoma cruzi replicative stages

Karunakaran A Kalesh, D. Fiedler, R. Docampo, 2020, Molecular microbiology.

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation

Karunakaran A Kalesh, P. Denny, K. Kalesh, 2019, bioRxiv.

A capillary electrophoresis method to explore the self‐assembly of a novel polypeptide ligand with quantum dots

Karunakaran A Kalesh, Lin Qiu, Liqian Gao, 2016, Electrophoresis.

Global profiling of protein lipidation using chemical proteomic technologies

Emmanuelle Thinon, Edward W. Tate, Karunakaran A Kalesh, 2015, Current opinion in chemical biology.

An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

Peter A. DiMaggio, Karunakaran A Kalesh, A. Snijders, 2019, Scientific Reports.

Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases

Karunakaran A Kalesh, A. Parthasarathy, Karunakaran Kalesh, 2020, RSC medicinal chemistry.

How can proteomics overhaul our understanding of Leishmania biology?

Karunakaran A Kalesh, P. Denny, K. Kalesh, 2020, Expert review of proteomics.

Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling

Karunakaran A Kalesh, P. Steel, Exequiel O J Porta, 2022, Frontiers in pharmacology.

A succinyl lysine-based photo-cross-linking peptide probe for Sirtuin 5.

Edward W. Tate, Karunakaran A Kalesh, E. Tate, 2014, Organic & biomolecular chemistry.

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.

Karunakaran A Kalesh, Pengyu Yang, S. Yao, 2009, Organic & biomolecular chemistry.

An Improved Mechanism‐Based Cross‐Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome

Karunakaran A Kalesh, S. Yao, Kai Liu, 2008, Chembiochem : a European journal of chemical biology.

Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics.

Karunakaran A Kalesh, E. Tate, Edward W Tate, 2015, Chemical communications.

Recent Advances in Synthesis and Identification of Cyclic Peptides for Bioapplications.

Su Seong Lee, Hongyan Sun, Liqian Gao, 2017, Current topics in medicinal chemistry.

Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane† †Electronic supplementary information (ESI) available: ProteomeXchange with identifier PXD006279. See DOI: 10.1039/c6cc08797c

Edward W. Tate, Karunakaran A Kalesh, E. Tate, 2017, Chemical communications.

Inhibition of HSP90 distinctively modulates the global phosphoproteome of Leishmania mexicana developmental stages

Karunakaran A Kalesh, P. Denny, Liqian Gao, 2023, bioRxiv.

The Use of Click Chemistry in the Emerging Field of Catalomics

S. Yao, Haibin Shi, Jingyan Ge, 2010 .