Alexander D James

Absorption, distribution, metabolism, and excretion of [14C]BYL719 (alpelisib) in healthy male volunteers

L. Trandafir, P. Swart, A. Jakab, 2015, Cancer Chemotherapy and Pharmacology.

A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance

W. Humphreys, R. Obach, C. Prakash, 2018, Drug Metabolism and Disposition.

Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

K. Schroer, E. Legangneux, A. Meissner, 2018, Drug Metabolism and Disposition.

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

G. Camenisch, Hilmar Schiller, Alexander David James, 2020, Pharmacology research & perspectives.

The Potential of Sutherlandia frutescens for Herb-Drug Interaction

P. Fasinu, Hilmar Schiller, H. Gutmann, 2013, Drug Metabolism and Disposition.

Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper

K. Cassidy, K. Georgi, G. Scarfe, 2022, Clinical pharmacology and therapeutics.

Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans

A. Meissner, G. Camenisch, Cyrille Marvalin, 2017, Drug Metabolism and Disposition.

19F-NMR-based determination of the absorption, metabolism and excretion of the oral phosphatidylinositol-3-kinase (PI3K) delta inhibitor leniolisib (CDZ173) in healthy volunteers

M. Walles, Alexander David James, David Pearson, 2018, Xenobiotica; the fate of foreign compounds in biological systems.