Y. Nguyen

发表

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

D. Ehrnhoefer, M. Hayden, N. Caron, 2018, Acta Neuropathologica Communications.

p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin.

D. Ehrnhoefer, M. Hayden, B. Leavitt, 2014, Human molecular genetics.

Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage

Shaun S. Sanders, M. Hayden, F. Lemarié, 2023, Frontiers in Physiology.

A human huntingtin SNP alters post-translational modification and pathogenic proteolysis of the protein causing Huntington disease

J. A. Collins, M. Hayden, J. Collins, 2017, bioRxiv.

Feeding schedule and proteolysis regulate autophagic clearance of mutant huntingtin

D. Ehrnhoefer, M. Hayden, N. Caron, 2017, bioRxiv.

Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound.

D. Ehrnhoefer, M. Hayden, A. Renslo, 2019, Cell chemical biology.

Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance

M. Hayden, Mandi E. Schmidt, D. Martin, 2017, bioRxiv.

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

D. Ehrnhoefer, M. Hayden, N. Caron, 2018, Acta neuropathologica communications.

Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

Shaun S. Sanders, M. Hayden, Xiaohong Xu, 2021, Neurobiology of Disease.

Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy

M. Collins, Y. Nguyen, F. Abrar, 2023, bioRxiv.