Alex C. Y. Chang

发表

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

Russ B Altman, Daniel Bernstein, Yong Fuga Li, 2016, Nature Medicine.

A Notch‐dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion

Steven J. M. Jones, M. Marra, Gordon Robertson, 2014, Developmental dynamics : an official publication of the American Association of Anatomists.

Investigation of Notch and nitric oxide signaling in the cardiovascular system

Alex C. Y. Chang, 2012 .

Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase.

M. Marra, P. Hoodless, A. Karsan, 2011, Developmental cell.

RUNX3 Maintains the Mesenchymal Phenotype after Termination of the Notch Signal*

A. Karsan, Kyle Niessen, Yangxin Fu, 2011, The Journal of Biological Chemistry.

Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development

P. Hoodless, A. Karsan, Victoria C Garside, 2012, Cellular and Molecular Life Sciences.

Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal.

Elizabeth D. Wederell, M. Marra, E. Wederell, 2010, Physiological genomics.

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Michael J. Gloudemans, Kevin S. Smith, H. Hakonarson, 2019, Nature Communications.

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.

P. Tsao, E. Ashley, D. Bernstein, 2018, American journal of physiology. Heart and circulatory physiology.

Differential Regulation of Transforming Growth Factor β Signaling Pathways by Notch in Human Endothelial Cells*

A. Karsan, Kyle Niessen, Yangxin Fu, 2009, The Journal of Biological Chemistry.

Short telomeres - A hallmark of heritable cardiomyopathies.

H. Blau, Alex C Y Chang, Alex C. Y. Chang, 2018, Differentiation; research in biological diversity.

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Joe Z. Zhang, H. Blau, Joseph C. Wu, 2019, Cell stem cell.

Targeting of CAT and VCAM1 as Novel Therapeutic Targets for DMD Cardiomyopathy

W. Liang, Ying-Ju Lin, Jian-Shiun Chiou, 2021, Frontiers in Cell and Developmental Biology.

Telomere shortening is a hallmark of genetic cardiomyopathies

E. Ashley, J. Seidman, H. Blau, 2018, Proceedings of the National Academy of Sciences.

Twist1 Transcriptional Targets in the Developing Atrio-Ventricular Canal of the Mouse

Steven J. M. Jones, M. Marra, M. Bilenky, 2012, PLoS ONE.

Humanizing the mdx mouse model of DMD: the long and the short of it

N. Rosenthal, H. Blau, J. Day, 2018, npj Regenerative Medicine.

Leukocyte Telomere Length Shortening Implies Plaque Instability and Major Adverse Cardiovascular Events in Patients With Angiographically Intermediate Lesions

Alex C Y Chang, Yu-qi Fan, Changqian Wang, 2022, Frontiers in Cardiovascular Medicine.

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy

H. Blau, A. Giaccia, Joseph C. Wu, 2016, Proceedings of the National Academy of Sciences.

Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload–Induced Heart Failure

G. Pandey, B. Mecham, I. Karakikes, 2020, Circulation. Heart failure.

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.

Joe Z. Zhang, H. Blau, D. Bers, 2019, European heart journal.

Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates

H. Blau, Foster Birnbaum, A. Eguchi, 2022, NPJ Regenerative medicine.

An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics.

M. Davies, H. Blau, E. Bertaccini, 2020, Anesthesia and analgesia.

Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates

H. Blau, Foster Birnbaum, A. Eguchi, 2022, npj Regenerative Medicine.

Secretion of miRNA-326-3p by senescent adipose exacerbates myocardial metabolism in diabetic mice

Jia-Yu Pan, Alex C Y Chang, Changqian Wang, 2022, Journal of translational medicine.

Insights into single hiPSC-derived cardiomyocyte phenotypes and maturation using ConTraX, an efficient pipeline for tracking contractile dynamics

Aleksandra K. Denisin, H. Blau, B. Pruitt, 2021, bioRxiv.

Notch-Dependent Regulation of the Ischemic Vasodilatory Response—Brief Report

A. Karsan, I. Laher, Alex C Y Chang, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells.

A. Karsan, A. Azad, H. Steed, 2013, Cellular signalling.

A Human iPSC Double-Rep orter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles Graphical Abstract Highlights

Joe Z. Zhang, H. Blau, Joseph C. Wu, 2019 .

Short telomeres - A hallmark of heritable cardiomyopathies.

H. Blau, Alex C. Y. Chang, 2018, Differentiation; research in biological diversity.

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.

Joe Z. Zhang, H. Blau, D. Bers, 2019, European heart journal.