J. Bryant

发表

Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517.

M. Adler, M. Whitlow, R. Feldman, 2007, Bioorganic & medicinal chemistry letters.

Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity.

M. Adler, M. Whitlow, R. Feldman, 2007, Bioorganic & medicinal chemistry letters.

Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1*

Marc Adler, M. Adler, M. Whitlow, 2005, Journal of Biological Chemistry.

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.

J. Morser, I. Islam, Shendong Yuan, 2008, Thrombosis research.

Host-guest complexation. 48. Octol building blocks for cavitands and carcerands

Enrico Dalcanale, Donald J. Cram, Linda M. Tunstad, 1989 .

Vases and kites as cavitands

Enrico Dalcanale, Donald J. Cram, E. Dalcanale, 1991 .

Structures of potent selective peptide mimetics bound to carboxypeptidase B.

M. Adler, M. Whitlow, J. Morser, 2008, Acta crystallographica. Section D, Biological crystallography.

Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B.

M. Adler, M. Whitlow, I. Islam, 2005, Biochemistry.

A novel P2Y12 adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models

C. Mallari, R. Vergona, W. Dole, 2007, Thrombosis and Haemostasis.

A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) – Part I: Pharmacological characterization

R. Vergona, M. Nagashima, J. Morser, 2006, Thrombosis and Haemostasis.

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization.

R. Vergona, W. Dole, J. Morser, 2008, Thrombosis research.

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).

M. Adler, M. Whitlow, R. Vergona, 2007, Bioorganic & medicinal chemistry letters.

Potent Triazolothione Inhibitor of Heat‐Shock Protein‐90

M. Adler, M. Whitlow, R. Feldman, 2009, Chemical biology & drug design.

Host-guest complexation. 55. Guest capture during shell closure

D. Cram, M. Vincenti, Judi A. Bryant, 1991 .

Differential Inhibition of Inducible T Cell Cytokine Secretion by Potent Iron Chelators

Hong-tao Lu, M. Berger, D. Schilling, 2005, Journal of biomolecular screening.

Host-guest complexation. 62. Solvophobic and entropic driving forces for forming velcraplexes, which are 4-fold, lock-key dimers in organic media

C. Knobler, D. Cram, Judi A. Bryant, 1992 .

Organic molecules dimerize with high structural recognition when each possesses a large lipophilic surface containing two preorganized and complementary host and guest regions

C. Knobler, D. Cram, J. Bryant, 1990 .

High preorganization of large lipophilic surfaces common to two complexing partners provides high binding free energies that vary dramatically with changes in organic solvent composition

D. Cram, Judi A. Bryant, J. Ericson, 1990 .

Host-guest complexation. 54. Spherands containing cyclic urea units

C. Knobler, D. Cram, S. Ho, 1990 .

Oxazoles Are Masked Carboxyls That Activate Ortho-Leaving Groups in Nucleophilic Aromatic Substitution

D. Cram, K. M. Doxsee, J. Bryant, 1987 .

Shell closures of tetrabenzyl chloride cavitands with tetrabenzylthiol cavitands provide carceplexes in which one or two guest molecules are incarcerated

D. Cram, M. Vincenti, Judi A. Bryant, 1990 .

Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process.

Wei Xu, M. Morrissey, I. Islam, 2018, Bioorganic & medicinal chemistry letters.