Thimo Kurz

发表

The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites

M. Peter, I. Zaidi, P. Pasero, 2006, Current Biology.

WNK signalling pathways in blood pressure regulation

M. Murthy, K. O’Shaughnessy, Thimo Kurz, 2016, Cellular and Molecular Life Sciences.

Degrade to create: developmental requirements for ubiquitin-mediated proteolysis during early C. elegans embryogenesis

B. Bowerman, Thimo Kurz, 2006, Development.

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase

M. Tyers, A. Willems, M. Peter, 2003, Nature.

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases

A. Knebel, Y. Thomas, N. Wood, 2016, Journal of Cell Science.

University of Dundee Characterization of the mammalian family of DCN-type NEDD 8 E 3 ligases

A. Knebel, Y. Thomas, N. Wood, 2016 .

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

Nurhan Özlü, A. Hyman, M. Peter, 2005, Nature.

Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia

N. Figg, A. Knebel, Frances-Rose Schumacher, 2015, EMBO molecular medicine.

University of Dundee Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and

Shaughnessy, Yasmin, N. Figg, 2015 .

The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes

I. Sumara, M. Peter, F. Sicheri, 2009, Proceedings of the National Academy of Sciences.

Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.

M. Tyers, A. Willems, M. Peter, 2008, Molecular cell.

Global proteomics of Ubqln2-based murine models of ALS

S. Gygi, J. Paulo, John Szpyt, 2020, bioRxiv.

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

M. Glickman, G. Bates, Roland Hjerpe, 2016, Cell.

A dual E3 mechanism for Rub1 ligation to Cdc53.

B. Schulman, R. Kriwacki, D. Duda, 2010, Molecular cell.

Cytoskeletal Regulation by the Nedd8 Ubiquitin-Like Protein Modification Pathway

P. Gönczy, M. Peter, J. Willis, 2002, Science.

University of Dundee Structural and biochemical characterization of the KLHL 3-WNK kinase interaction important in blood pressure regulation

D. Alessi, A. Bullock, Frances-Rose Schumacher, 2014 .

The TFIIH subunit Tfb3 regulates cullin neddylation.

M. Peter, Charles Boone, Taras Makhnevych, 2011, Molecular cell.

The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

D. Alessi, A. Knebel, Thomas Macartney, 2013, The Biochemical journal.

Neddylation and Deneddylation of CUL-3 Is Required to Target MEI-1/Katanin for Degradation at the Meiosis-to-Mitosis Transition in C. elegans

M. Peter, J. Willis, B. Bowerman, 2003, Current Biology.

CSN- and CAND1-dependent remodelling of the budding yeast SCF complex

G. Rabut, A. Knebel, Y. Thomas, 2013, Nature Communications.

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

L. Dick, Roland Hjerpe, Y. Thomas, 2011, The Biochemical journal.

Unanchored tri‐NEDD8 inhibits PARP‐1 to protect from oxidative stress‐induced cell death

Roland Hjerpe, R. Gourlay, M. Trost, 2019, The EMBO journal.

Unanchored tri‐NEDD8 inhibits PARP‐1 to protect from oxidative stress‐induced cell death

Roland Hjerpe, R. Gourlay, M. Trost, 2019, The EMBO journal.

ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403‐459 mutation

K. O'Shaughnessy, T. Kurz, M. Murthy, 2016, Physiological reports.

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

M. Tatham, J. Chin, R. Hay, 2014, The Biochemical journal.

The Dac-tag, an affinity tag based on penicillin-binding protein 5.

M. Peggie, M. Deák, R. Toth, 2012, Analytical biochemistry.

University of Dundee The NEDD 8 E 3 ligase DCNL 5 is phosphorylated by IKK alpha during Toll-like receptor activation

Philip R. Cohen, J. Rinehart, Y. Thomas, 2018 .

NEDD8 overexpression results in neddylation of ubiquitin substrates by the ubiquitin pathway.

Roland Hjerpe, Y. Thomas, Thimo Kurz, 2012, Journal of molecular biology.

University of Dundee UBQLN 2 mediates autophagy-independent protein aggregate clearance by the proteasome

M. Glickman, G. Bates, Roland Hjerpe, 2022 .

The COP9 signalosome is vital for timely repair of DNA double-strand breaks

Daniel A. Chamovitz, Yosef Shiloh, David M. Bodine, 2015, Nucleic acids research.

The COP 9 signalosome is vital for timely repair of DNA double-strand breaks

Y. Shiloh, Y. Galanty, D. Bodine, 2015 .

The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

P. Cohen, J. Rinehart, Y. Thomas, 2018, PloS one.

Cullin neddylation and substrate‐adaptors counteract SCF inhibition by the CAND1‐like protein Lag2 in Saccharomyces cerevisiae

M. Peter, K. Hofmann, B. Schulman, 2009, The EMBO journal.

Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation

D. Alessi, A. Bullock, Frances-Rose Schumacher, 2014, The Biochemical journal.

RNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical Stress

B. Sönnichsen, M. Hannus, Frances-Rose Schumacher, 2016, PloS one.

University of Dundee RNAi screen for NRF 2 inducers identifies targets that rescue primary lung epithelial cells from cigarette smoke induced radical stress

B. Sönnichsen, M. Hannus, Frances-Rose Schumacher, 2016 .