D. McPherson

发表

Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer’s disease

G. Sedvall, C. Halldin, L. Farde, 2000, Psychopharmacology.

Z-(-,-)-[76Br]BrQNP : A high affinity PET radiotracer for central and cardiac muscarinic receptors

B. Maziére, F. Knapp, C. Coulon, 1996 .

Evaluation of 1-azabicyclo[2.2.2]oct-3-yl α-fluoroalkyl-α-hydroxy-α-phenylacetates as potential ligands for the study of muscarinic receptor density by positron emission tomography

R. Reba, F. Knapp, D. Mcpherson, 1996 .

Radiolabeling of proteins with radioisotopes of copper using p‐carboxyalkylphenylglyoxal bis‐(4N‐methylthiosemicarbazone) (TSC) bifunctional chelates

G. Umbricht, F. F. Knapp, D. Mcpherson, 1990 .

Synthesis of some 3-(1-azabicyclo[2.2.2]octyl) 3-amino-2-hydroxy-2-phenylpropionates: profile of antimuscarinic efficacy and selectivity.

C. Kaiser, J. Kachur, M. Abreu, 1990, Journal of medicinal chemistry.

Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists.

J. Ferkany, D. Mcpherson, L. Noronha-Blob, 1988, Journal of medicinal chemistry.

Resolution, in vitro and in vivo evaluation of fluorine‐18‐labeled isomers of 1‐azabicyclo[2.2.2]oct‐3‐ylα‐(1‐fluoropent‐5‐yl)α‐hydroxy‐α‐phenylacetate (FQNPe) as new PET candidates for the imaging of muscarinic‐cholinergic receptor

F. Knapp, A. Beets, D. Mcpherson, 1998 .

Structure Elucidation Via Stereoselective Synthesis of the Acetate Center of 1-Azabicyclo[2.2.2]oct-3-yl alpha-Hydroxy- alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate (IQNP). A High Affinity Muscarinic Imaging Agent for SPECT.

F. Knapp, D. Mcpherson, D. McPherson, 1996, The Journal of organic chemistry.

Serial PET studies of human cerebral malignancy with [1-11C]putrescine and [1-11C]2-deoxy-D-glucose.

N. Volkow, J. Brodie, A. Wolf, 1987, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

A comparison of the brain uptake of N-(cyclopropyl[11C]methyl)norbuprenorphine ([11C]buprenorphine) and N-(cyclopropyl[11C]methyl)nordiprenorphine ([11C]diprenorphine) in baboon using PET.

A. Wolf, J. Fowler, J. Logan, 1991, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

The use of alumina “SepPaks®” as a simple method for the removal and determination of tungsten-188 breakthrough from tungsten-188/rhenium-188 generators

S. Mirzadeh, F. Knapp, A. P. Callahan, 1992 .

Rhenium-188-HEDP-kit Formulation and Quality Control

F. Knapp, J. Gaudiano, E. León, 1997 .

Site-specific/stable radioiodination of 1,2-Pal-3-IPPA: an agent for the potential clinical evaluation of pancreatic insufficiency by urine analysis.

G. Kirsch, F. Knapp, H. Biersack, 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Evaluation of Z-(R,R)-IQNP for the potential imaging of m2 mAChR rich regions of the brain and heart.

F. Knapp, A. Beets, H. Luo, 2000, Life sciences.

Stereoselective synthesis, in vitro, and initial in vivo evaluation of 1-methylpiperidin-4-yl α-hydroxy-α-(1-iodo-1-propen-3-yl)-α-phenylacetate (IPIP): a novel radioiodinated molecular probe with high affinity for the muscarinic receptor

F. Knapp, A. Beets, H. Luo, 2001 .

Targeting Cerebral Muscarinic Acetylcholine Receptors with Radioligands for Diagnostic Nuclear Medicine Studies

D. Mcpherson, D. McPherson, 2001 .

Response to “Comment on ‘In vivo biodistribution of and internal dosimetry of radioiodinated agents selective to the muscarinic acetylcholinergic receptor complex’ ” [Med. Phys. 27, 2190 (2000)]

W. Breeden, D. McPherson, 2000 .

Resolution and in vitro and initial in vivo evaluation of isomers of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate: a high-affinity ligand for the muscarinic receptor.

C. R. Lambert, B. Zeeberg, K. Jahn, 1995, Journal of medicinal chemistry.

Characterization of in vivo brain muscarinic acetylcholine receptor subtype selectivity by competition studies against (R,S)-[125 I]QNB

B. Zeeberg, R. Reba, M. Gitler, 1995, Brain Research.

Synthesis and biodistribution of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate. A new ligand for the potential imaging of muscarinic receptors by single photon emission computed tomography.

D. DeHaven-Hudkins, F. F. Knapp, D. Mcpherson, 1993, Journal of medicinal chemistry.

Analogues of oxybutynin. Synthesis and antimuscarinic and bladder activity of some substituted 7-amino-1-hydroxy-5-heptyn-2-ones and related compounds.

C. Kaiser, C. Spagnuolo, K. Natalie, 1991, Journal of medicinal chemistry.

[18F]-N-Methylspiroperidol: the radioligand of choice for PETT studies of the dopamine receptor in human brain.

J S Fowler, C. D. Arnett, A. Wolf, 1985, Life sciences.

In vivo metabolic studies of thetrans-(R,R) isomer of radioiodinated IQNP: A new ligand with high affinity for the M1 muscarinic-cholinergic receptor

F. Knapp, F. Knapp, C. R. Lambert, 1994, European Journal of Nuclear Medicine.

Evaluation and metabolite studies of 125I- and 123I-labelled E-(R,R)-IQNP: potential radioligands for visualization of M1 muscarinic acetylcholine receptors in brain.

C. Halldin, N. Ginovart, L. Farde, 1998, Nuclear medicine and biology.

No-carrier-added fluorine-18-labeled N-methylspiroperidol: synthesis and biodistribution in mice.

C. D. Arnett, A. Wolf, J. Fowler, 1986, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis and antimuscarinic activity of some 1-cycloalkyl-1-hydroxy-1-phenyl-3-(4-substituted piperazinyl)-2-propanones and related compounds.

C. Kaiser, D. Mcpherson, L. Noronha-Blob, 1993, Journal of medicinal chemistry.

Reaction of atomic carbon with ammonia. The mechanism of formation of amino acid precursors

P. Shevlin, P. Melius, D. McPherson, 1983 .

In vivo competition studies of Z-(-,-)-[125I]IQNP against 3-quinuclidinyl 2-(5-bromothienyl)-2-thienylglycolate (BrQNT) demonstrating in vivo m2 muscarinic subtype selectivity for BrQNT

V. Cohen, V. Sood, S. F. Boulay, 1998, Journal of Molecular Neuroscience.

Characterization of in vivo brain muscarinic acetylcholine receptor subtype selectivity by competition studies against (R,S)-[125I]IQNB (Brain Res. 687 (1995) 71–78) BRES 11314)

R. Reba, M. Gitler, F. Knap, 1995, Brain Research.

Synthesis and biodistribution of no-carrier-added [1-11C]putrescine.

N. Volkow, J. Brodie, A. Wolf, 1985, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In vivo biodistribution of 125IPIP and internal dosimetry of 123IPIP radioiodinated agents selective to the muscarinic acetylcholinergic receptor complex.

D. Hamby, K. Eckerman, J. Carey, 2000, Medical physics.

Synthesis and biological evaluation of iodine-125 iodocaramiphen. A potential M1 muscarinic imaging agent for SPECT

R. Hudkins, F. F. Knapp, D. Mcpherson, 1994 .

A simple one-pot synthesis of cyclopropane [11C]carbonyl chloride. Synthesis and biodistribution of [11C]cyclorphan†

C. D. Arnett, A. Wolf, D. Hwang, 1986 .

Dual-label studies with [125I]-3(R)/[131I]-3(S)-BMIPP show similar metabolism in rat tissues.

A. Bockisch, F. Mokler, F. Knapp, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effects of configuration on the myocardial uptake of radioiodinated 3(R)-BMIPP and 3(S)-BMIPP in rats.

F. Mokler, F. Knapp, J. Kropp, 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Evaluation of pancreatic lipase activity by simple urine analysis after oral administration of a new iodine-131-labeled triglyceride

H. Biersack, K. R. Ambrose, J. Kropp, 1994, European Journal of Nuclear Medicine.

Nuclear Medicine Program progress report for quarter ending June 30, 1990

J. F. Allred, S. Mirzadeh, F. Knapp, 1993 .

The formation of amino acid precursors in the reaction of atomic carbon with water and ammonia at 77 K

P. Shevlin, D. Mcpherson, K. Rahman, 2006, Origins of life and evolution of the biosphere.

An experimental and theoretical evaluation of the mechanism of hydrocyanic acid formation in the reaction between atomic carbon and ammonia

P. Shevlin, M. Mckee, D. McPherson, 1983 .

Nuclear medicine program progress report for quarter ending September 30, 1995

S. Mirzadeh, F. Knapp, A. Beets, 1995 .

SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP

G. Sedvall, C. Halldin, L. Farde, 2001, European Journal of Nuclear Medicine.