E. Labonté

发表

Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD.

Andrew G. Spencer, D. Charmot, M. Navre, 2015, Journal of the American Society of Nephrology : JASN.

Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.

P. Howles, P. Tso, Y. Ioannou, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Intestinal Inhibition of the Na+/H+ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na+ Uptake in Humans

Andrew G. Spencer, D. Charmot, M. Navre, 2014, Science Translational Medicine.

Expression of cholesterol 7alpha-hydroxylase restores bile acid synthesis in McArdle RH7777 cells.

L. Agellon, Q. Li, E. Labonté, 2000, Archives of biochemistry and biophysics.

RDX5791, a First-in-Class Minimally Systemic NHE3 Inhibitor in Clinical Development for CIC and IBS-C, Increases Intestinal Sodium Leading to Enhanced Intestinal Fluid Volume and Transit

Andrew G. Spencer, D. Charmot, M. Navre, 2011 .

Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na+/H+ Exchanger Isoform 3

Andrew G. Spencer, D. Charmot, M. Navre, 2022, ACS medicinal chemistry letters.

Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A2 and diet‐induced obesity

P. Pfluger, M. Tschöp, R. Jandacek, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The relative ligand binding preference of the murine ileal lipid binding protein.

C. Kay, L. Agellon, Qianqian Li, 2003, Protein expression and purification.

Group 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia.

K. Huggins, D. Hui, R. Kirby, 2006, Diabetes.

Separation and quantitation of bile acids using an isocratic solvent system for high performance liquid chromatography coupled to an evaporative light scattering detector.

L. Agellon, E. Labonté, E. Torchia, 2001, Analytical biochemistry.

Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption.

P. Howles, D. Hui, E. Labonté, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Carboxyl Ester Lipase Deficiency Exacerbates Dietary Lipid Absorption Abnormalities and Resistance to Diet-induced Obesity in Pancreatic Triglyceride Lipase Knockout Mice*

P. Howles, R. Jandacek, D. Hui, 2007, Journal of Biological Chemistry.

Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.

P. Howles, Y. Ioannou, D. Hui, 2007, Biochimica et biophysica acta.

Preclinical and Healthy Volunteer Studies of Potential Drug–Drug Interactions Between Tenapanor and Phosphate Binders

Andrew G. Spencer, D. Charmot, K. Kozuka, 2016, Clinical pharmacology in drug development.