Yutong Zhang

Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery

M. Weirauch, B. Namjou, J. Harley, 2022, Nature Communications.

CRISPRa screen on a genetic risk locus shared by multiple autoimmune diseases identifies a dysfunctional enhancer that affects IRF8 expression through cooperative lncRNA and DNA methylation machinery

M. Weirauch, B. Namjou, J. Harley, 2021, bioRxiv.

Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus

Yongfei Wang, Yuanjia Tang, N. Shen, 2022, Arthritis & rheumatology.

Non-coding DNA variants for risk in lupus.

Guojun Hou, Yutong Zhang, Nan Shen, 2024, Best practice & research. Clinical rheumatology.

SPATS2L is a positive feedback regulator of the type I interferon signaling pathway and plays a vital role in lupus.

Guojun Hou, Yue Yang, Wanling Yang, 2024, Acta biochimica et biophysica Sinica.

704 Global identification of lupus genetic risk variants modulating the type I interferon pathway through CRISPR-based genomic screening

Guojun Hou, Xinyi Zhu, Zhaorui Cheng, 2024, Epidemiology & Outcomes.

Three‐Dimensional Chromosomal Landscape Revealing miR‐146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR‐Mediated Approach to Inhibit the Interferon Pathway

Yuanjia Tang, Jianyang Ma, Z. Yin, 2023, Arthritis & rheumatology.