Keiko Doi

发表

SPA‐1 controls the invasion and metastasis of human prostate cancer

T. Yamasaki, N. Minato, Tomomi Yamada, 2011, Cancer science.

M. Kuroki, S. Shirasawa, T. Sasazuki, 2010, Proceedings of the National Academy of Sciences.

ZFAT is an antiapoptotic molecule and critical for cell survival in MOLT‐4 cells

S. Shirasawa, T. Sasazuki, T. Tsunoda, 2009, FEBS letters.

Controlled intracellular localization and enhanced antisense effect of oligonucleotides by chemical conjugation.

M. Fujii, H. Ohba, T. Kubo, 2005, Organic & biomolecular chemistry.

Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

M. Kuroki, S. Shirasawa, T. Sasazuki, 2010, Neoplasia.

The roles of ZFAT in thymocyte differentiation and homeostasis of peripheral naive T-cells.

S. Shirasawa, K. Doi, S. Ishikura, 2014, Anticancer research.

Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS.

G. Baillie, S. Shirasawa, T. Tsunoda, 2017, Anticancer research.

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line

S. Shirasawa, T. Tsunoda, S. Ishikura, 2017, Cell Death & Disease.

Resveratrol Overcomes Cellular Resistance to Vemurafenib Through Dephosphorylation of AKT in BRAF-mutated Melanoma Cells.

S. Shirasawa, T. Tsunoda, Masayo Umebayashi, 2016, Anticancer research.

Altered Energy Homeostasis and Resistance to Diet-Induced Obesity in KRAP-Deficient Mice

N. Kato, S. Shirasawa, T. Sasazuki, 2009, PloS one.

The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway*

S. Shirasawa, T. Okamura, T. Tsunoda, 2016, The Journal of Biological Chemistry.

FoxO 1 regulation by Zfat via autophagy and Akt-signaling 1 The nuclear zinc-finger protein Zfat maintains FoxO 1 protein levels in peripheral T cells by regulating activities of autophagy and Akt-signaling pathway

S. Shirasawa, T. Okamura, T. Tsunoda, 2016 .

Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.

S. Shirasawa, T. Okamura, T. Tsunoda, 2015, Anticancer research.

Marked Reduction in FoxO 1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells

S. Shirasawa, T. Okamura, T. Tsunoda, 2015 .

ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response.

M. Kuroki, S. Shirasawa, T. Sasazuki, 2012, Biochemical and biophysical research communications.

Oncogenic KRAS regulates miR-200c and miR-221/222 in a 3D-specific manner in colorectal cancer cells.

M. Kuroki, S. Shirasawa, T. Sasazuki, 2011, Anticancer research.

Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver

S. Shirasawa, T. Tsunoda, Yoko Tanaka, 2019, AntiCancer Research.

Zfat expression in ZsGreen reporter gene knock-in mice: Implications for a novel function of Zfat in definitive erythropoiesis

S. Shirasawa, T. Okamura, T. Tsunoda, 2018, International journal of molecular medicine.

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.

S. Shirasawa, T. Kawai, T. Okamura, 2016, Biochimica et biophysica acta.

Zfat‐Deficient CD4+CD8+ Double‐Positive Thymocytes Are Susceptible to Apoptosis With Deregulated Activation of p38 and JNK

S. Shirasawa, T. Okamura, T. Tsunoda, 2015, Journal of cellular biochemistry.

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection

S. Shirasawa, T. Sasazuki, T. Okamura, 2013, PloS one.

ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts

M. Kuroki, S. Shirasawa, T. Sasazuki, 2010, Cellular & Molecular Biology Letters.

ZFAT is essential for endothelial cell assembly and the branch point formation of capillary-like structures in an angiogenesis model

M. Kuroki, S. Shirasawa, T. Sasazuki, 2010, Cellular & Molecular Biology Letters.

ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes.

N. Kato, S. Shirasawa, T. Sasazuki, 2008, Genomics.

ALPK2 is crucial for luminal apoptosis and DNA repair-related gene expression in a three-dimensional colonic-crypt model.

M. Kuroki, S. Shirasawa, T. Tsunoda, 2012, Anticancer research.

Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes

Masatoshi Tanaka, S. Shirasawa, T. Tsunoda, 2012, FEBS open bio.

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line

S. Shirasawa, T. Tsunoda, S. Ishikura, 2017, Cell Death & Disease.

Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia

N. Minato, M. Vooijs, C. Kressler, 2015, Scientific Reports.

KRAS-induced actin-interacting protein is required for the proper localization of inositol 1,4,5-trisphosphate receptor in the epithelial cells.

M. Kuroki, S. Shirasawa, T. Okamura, 2011, Biochemical and biophysical research communications.

Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture.

S. Shirasawa, T. Tsunoda, K. Doi, 2014, Anticancer research.

KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines.

M. Kuroki, S. Shirasawa, T. Sasazuki, 2011, Anticancer research.

KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release.

M. Kuroki, S. Shirasawa, T. Tsunoda, 2011, Biochemical and biophysical research communications.

An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.

M. Muramatsu, S. Shirasawa, T. Tsunoda, 2017, Anticancer Research.

Molecular Hierarchy of Heparin-Binding EGF-like Growth Factor–Regulated Angiogenesis in Triple-Negative Breast Cancer

E. Tokunaga, E. Oki, Y. Maehara, 2013, Molecular Cancer Research.

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model

S. Miyamoto, M. Kuroki, D. Tyson, 2012, Molecular Cancer.

KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells.

S. Miyamoto, M. Kuroki, S. Shirasawa, 2012, Anticancer research.

1 KRAS Upregulates miR-181 a , miR-200 c and miR-210 in a Three-Dimensional-Specific Manner in DLD-1 Colorectal Cancer Cells

S. Miyamoto, M. Kuroki, S. Shirasawa, 2015 .

Title Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia

N. Minato, M. Vooijs, C. Kressler, 2017 .

Establishment of a Three-dimensional Floating Cell Culture System for Screening Drugs Targeting KRAS-mediated Signaling Molecules.

S. Shirasawa, T. Tsunoda, K. Doi, 2015, Anticancer research.

Determination of the critical region of KRAS-induced actin-interacting protein for the interaction with inositol 1,4,5-trisphosphate receptor.

M. Kuroki, S. Shirasawa, T. Tsunoda, 2011, Biochemical and biophysical research communications.