Georgia Spain

Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

M. Gerlinger, M. Davies, K. von Loga, 2018, bioRxiv.

Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

M. Gerlinger, M. Davies, K. von Loga, 2018, bioRxiv.

Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

G. Sauter, M. Gerlinger, A. Marx, 2019, Nature Communications.

Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the secretomes of three‐dimensional genetic models of ovarian carcinogenesis

S. Gayther, J. Timms, H. Sowter, 2015, International journal of cancer.

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

Brian J. Stevenson, G. Coukos, M. Gerlinger, 2019, Journal of Immunotherapy for Cancer.

Effects of ErbB2 Overexpression on the Proteome and ErbB Ligand-specific Phosphosignaling in Mammary Luminal Epithelial Cells *

J. Timms, J. Worthington, G. Spain, 2017, Molecular & Cellular Proteomics.

CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids

M. Gerlinger, K. von Loga, D. Cunningham, 2019, Journal of Immunotherapy for Cancer.

Investigating the mehcanisms of drug resistance in gastro-intestinal cancers

M. Gerlinger, G. Spain, G. Spain, 2020 .