J. Brewer

发表

Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE

Keith A. Johnson, Scott Ayton, Joanne L. Lord, 2015, Nature Communications.

The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores

Mark T. W. Ebbert, Raymond Scott Turner, Owen Carmichael, 2021, Communications Biology.

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Sterling C. Johnson, Christine L. Tardif, John X. Morris, 2021, Nature Communications.

A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Communications Medicine.

Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

Sterling C. Johnson, David T. Jones, Taylor W. Schmitz, 2016, Nature Communications.

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2019, Nature Communications.

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

Sterling C. Johnson, John X. Morris, Keith A. Johnson, 2021, Nature Medicine.

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Keith A. Johnson, Sherye A. Sirrel, Alice D. Brown, 2019, Scientific Reports.

Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Communications.

Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease

Martha Brumfield, Robin Wolz, Marina Boccardi, 2014, Alzheimer's & Dementia.

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

Effect of CR1 Genetic Variants on Cerebrospinal Fluid and Neuroimaging Biomarkers in Healthy, Mild Cognitive Impairment and Alzheimer's Disease Cohorts

Keith A. Johnson, Joanne L. Lord, Colleen S. Albers, 2016, Molecular Neurobiology.

Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Communications.

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2021, Translational Psychiatry.

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2021, Nature Communications.

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, GeroScience.

Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau

Sterling C. Johnson, Nick C Fox, John X. Morris, 2020, Brain communications.

The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum

Sterling C. Johnson, Keith A. Johnson, Joanne L. Lord, 2016, Scientific Reports.

The trend of disruption in the functional brain network topology of Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2021, Scientific Reports.

Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2022, GeroScience.

Intranasal insulin modulates cerebrospinal fluid markers of neuroinflammation in mild cognitive impairment and Alzheimer’s disease: a randomized trial

R. Raman, S. Craft, R. Rissman, 2022, Scientific reports.

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2017, Nature Communications.

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2023, Communications Medicine.

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Aging.

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

Norbert Schuff, Michael W. Weiner, Robert C. Green, 2019, Scientific Reports.

Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status

Sterling C. Johnson, Nick C Fox, Keith A. Johnson, 2021, Translational Psychiatry.

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Sterling C. Johnson, Keith A. Johnson, Joanne L. Lord, 2019, Nature Communications.

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Keith A. Johnson, Raymond Scott Turner, Charles D. Smith, 2022, Nature Aging.

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Islem Rekik, Mohamed Ali Mahjoub, Keith A. Johnson, 2018, Scientific Reports.

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2019, Nature Communications.

Assessing the Clinical Meaningfulness of the Alzheimer’s Disease Composite Score (ADCOMS) Tool

B. Hyman, A. Saykin, J. Kaye, 2022, Neurology and Therapy.

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

Keith A. Johnson, Michael W. Paul Ronald Clifford R. Andrew J. William John Weiner Aisen Petersen Jack Saykin Jagust , Sherye A. Sirrel, 2019, Scientific Reports.

Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2021, Nature Communications.

A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Sherye A. Sirrel, 2020, Scientific Reports.

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

K. Lunetta, D. Geschwind, H. Hakonarson, 2020, JAMA neurology.

Non-coding variability at the APOE locus contributes to the Alzheimerâ€TMs risk

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2019 .

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

John X. Morris, Keith A. Johnson, Raymond Scott Turner, 2019, Scientific Reports.

GenEpi: gene-based epistasis discovery using machine learning

Michael W. Weiner, Yen-Jen Oyang, Arthur W. Toga, 2018, BMC Bioinformatics.

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

Sterling C. Johnson, David T. Jones, Keith A. Johnson, 2020, Nature Communications.

Predicting Short-term Progression Using Imaging, Factors, and Demographics.

Hosein, Mauricio, M. Mintun, 2019 .

A blood-based signature of cerebrospinal fluid Aβ1–42 status

John X. Morris, Keith A. Johnson, Raymond Scott Turner, 2019, Scientific Reports.

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2018, Scientific Reports.

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Aging.

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Sterling C. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment

John X. Morris, Keith A. Johnson, Raymond Scott Turner, 2023, BMC Geriatrics.

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer disease: the Alzheimer Disease Genetics Consortium

John X. Morris, Nicholas R. Wheeler, Timothy J. Hohman, 2023, medRxiv.

A blood-based signature of cerebrospinal fluid Aβ1–42 status

Raymond Scott Turner, Sherye A. Sirrel, Alice D. Brown, 2019, Scientific Reports.

In vivo cortical diffusion imaging relates to Alzheimer’s disease neuropathology

S. Chance, C. DeCarli, R. Vassar, 2023, Alzheimer's Research & Therapy.

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Sterling C. Johnson, Sherye A. Sirrel, Alice D. Brown, 2015, Nature Communications.

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

Sterling C. Johnson, Raymond Scott Turner, Alice D. Brown, 2020, Molecular neurodegeneration.

Pavel P. Kuksa, Nicholas R. Wheeler, Timothy J. Hohman, 2023, medRxiv.

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

James B. Brewer, Raymond Scott Turner, Paul S. Aisen, 2015, Neurology.

Polygenic effects on the risk of Alzheimer’s disease in the Japanese population

Raymond Scott Turner, Sherye A. Sirrel, Alice D. Brown, 2024, Alzheimer's research & therapy.

Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease

S. Risacher, K. Nho, S. Mazmanian, 2024, Scientific reports.

Impact of amyloid and cardiometabolic risk factors on prognostic capacity of plasma neurofilament light chain for neurodegeneration

Sherye A. Sirrel, Alice D. Brown, Christina A. Michel, 2024, Alzheimer's research & therapy.