Frédérique Pilon

Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation

S. Bourgault, J. Delisle, S. Crespo-Garcia, 2021, EMBO molecular medicine.

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.

Frédérick A. Mallette, C. Yohn, C. Beauséjour, 2021, Cell metabolism.

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

Frédérick A. Mallette, G. Andelfinger, J. Côté, 2020, Science.

Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life

S. Crespo-Garcia, P. Sapieha, Jean-Sébastien Joyal, 2023, The Journal of clinical investigation.

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

T. Langmann, C. Des Rosiers, C. Daneault, 2023, Science.

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome

G. Lettre, M. Meunier, M. Laplante, 2018, Science Immunology.

miR-106b suppresses pathological retinal angiogenesis

V. de Guire, S. Crespo-Garcia, P. Sapieha, 2020, Aging.

Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis

Frédérick A. Mallette, B. Larrivée, S. Crespo-Garcia, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Corticosteroids prevent pathological angiogenesis yet compromise reparative vascular remodeling in the retina

P. Sapieha, G. Cagnone, A. Dejda, 2024, bioRxiv.