Vera Guber

Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

Frédérick A. Mallette, R. Kaufman, F. Mallette, 2016, Science Translational Medicine.

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.

Frédérick A. Mallette, C. Yohn, C. Beauséjour, 2021, Cell metabolism.

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

Frédérick A. Mallette, G. Andelfinger, J. Côté, 2020, Science.

Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life

S. Crespo-Garcia, P. Sapieha, Jean-Sébastien Joyal, 2023, The Journal of clinical investigation.

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

T. Langmann, C. Des Rosiers, C. Daneault, 2023, Science.

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

Frédérick A. Mallette, J. Gratton, Katie Bentley, 2019, Proceedings of the National Academy of Sciences.