M. Saier

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Identification of a transcription factor, PunR, that regulates the purine and purine nucleoside transporter punC in E. coli

Anand V. Sastry, D. Rodionov, Y. Hefner, 2021, Communications Biology.

Comparative genomic analyses of transport proteins encoded within the red algae Chondrus crispus, Galdieria sulphuraria, and Cyanidioschyzon merolae11

Shounak Ghosh, M. Saier, Justin Lee, 2017, Journal of phycology.

Amiloride‐resistant Madin‐Darby Canine kidney (MDCK) cells exhibit decreased cation transport

M. Taub, M. Saier, 1981, Journal of cellular physiology.

Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole‐genome analyses

W. Weyler, B. Schneider, M. Moreno, 2001, Molecular microbiology.

In Vitro Reconstitution of Transcriptional Antitermination by the SacT and SacY Proteins of Bacillus subtilis*

M. Arnaud, M. Débarbouillé, G. Rapoport, 1996, The Journal of Biological Chemistry.

Multidrug‐Resistant Transport Proteins in Yeast: Complete Inventory and Phylogenetic Characterization of Yeast Open Reading Frames within the Major Facilitator Superfamily

M H Saier, A. Goffeau, I. Paulsen, 1997, Yeast.

Horizontal transfer of a phosphatase gene as evidence for mosaic structure of the Salmonella genome.

H. Ochman, E. Groisman, M. Saier, 1992, The EMBO journal.

A mechanism of transposon‐mediated directed mutation

Zhongge Zhang, M. Saier, 2009, Molecular microbiology.

Is FatP a long‐chain fatty acid transporter?

M. Saier, Justin M. Kollman, 1999, Molecular microbiology.

Differential codon usage: a safeguard against inappropriate expression of specialized genes?

M. Saier, 1995, FEBS letters.

The bile/arsenite/riboflavin transporter (BART) superfamily

Christian Vogl, Dorjee G. Tamang, Milton H Saier, 2007, The FEBS journal.

Adaptive regulatory control of system a transport activity in a kidney epithelial cell line (MDCK) and in a transformed variant (MDCK‐T1)

M. Saier, P. Boerner, M. Saier, 1985, Journal of cellular physiology.

Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery

Hassan Zafar, M. Saier, 2023, Cells.

Hormonal regulation of the system a amino acid transport adaptive response mechanism in a kidney epithelial cell line (MDCK)

P. Boerner, M. Saier, 1985, Journal of Cellular Physiology.

BioV Suite – a collection of programs for the study of transport protein evolution

Milton H Saier, V. Reddy, Vamsee S Reddy, 2012, The FEBS journal.

Effect of the FruR Regulator on Transcription of the pts Operon in Escherichia coli(*)

M H Saier, V. Michotey, S. Garges, 1995, The Journal of Biological Chemistry.

E. coli allantoinase is activated by the downstream metabolic enzyme, glycerate kinase, and stabilizes the putative allantoin transporter by direct binding

P. Uetz, M. Babu, Zhongge Zhang, 2023, Scientific reports.

The bacterial phosphotransferase system: Kinetic characterization of the glucose, mannitol, glucitol, and N‐acetylglucosamine systems

E. Waygood, F. Grenier, M. Saier, 1986, Journal of cellular biochemistry.

Regulation of Lactose Transport by the Phosphoenolpyruvate‐Sugar Phosphotransferase System in Membrane Vesicles of Escherichia coli

M. Saier, S. Dills, M. R. Schmidt, 1982, Journal of cellular biochemistry.

Analysis of the gluconate (gnt) operon of Bacillus subtilis

M. Saier, J. Deutscher, J. Reizer, 1991, Molecular microbiology.

Nucleotide sequence of the region between crr and cysM in Salmonella typhimurium: five novel ORFs including one encoding a putative transcriptional regulator of the phosphotransferase system.

J. Reizer, A. Reizer, F. Titgemeyer, 1995, DNA sequence : the journal of DNA sequencing and mapping.

Novel phosphotransferase systems revealed by bacterial genome analysis: the complete repertoire of pts genes in Pseudomonas aeruginosa.

M. Saier, J. Reizer, A. Reizer, 1999, Journal of molecular microbiology and biotechnology.

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

S. Lory, M. Olson, G. K. Wong, 2000, Nature.

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

G. Hortobagyi, E. Gehan, D. Greenblatt, 1979, Cancer research.

Microbial genome analyses: comparative transport capabilities in eighteen prokaryotes.

I. Paulsen, M. Saier, L. Nguyen, 2000, Journal of molecular biology.

Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities.

M H Saier, I. Paulsen, M. Saier, 1998, Journal of molecular biology.

Modular multidomain phosphoryl transfer proteins of bacteria.

M. Saier, J. Reizer, M. Saier, 1997, Current opinion in structural biology.

Phylogeny of multidrug transporters.

M H Saier, I. Paulsen, M. Saier, 2001, Seminars in cell & developmental biology.

Comparative genomics of microbial drug efflux systems.

K. Nelson, I. Paulsen, M. Saier, 2001, Journal of molecular microbiology and biotechnology.

TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters.

M. Saier, R. Rabus, D. Jack, 1999, Microbiology.

Comparative genomics of the lactic acid bacteria

Katherine H. Huang, N. V. Pavlova, E. Koonin, 2006, Proceedings of the National Academy of Sciences.

Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution.

M. Wittekind, M. Saier, R. Klevit, 1989, Biochemistry.

The drug/metabolite transporter superfamily.

M H Saier, Nelson M. Yang, M. Saier, 2001, European journal of biochemistry.

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.

M H Saier, A. Goffeau, M. Saier, 1999, Journal of molecular microbiology and biotechnology.

Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria.

I. Paulsen, M. Saier, M. Sliwinski, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A family of gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from gram-negative bacteria.

M H Saier, I. Paulsen, M. Saier, 1997, FEMS microbiology letters.

A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria

M H Saier, I. Paulsen, M. Saier, 1994, Journal of bacteriology.

Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria

M H Saier, M. Saier, R. Tam, 1993, Microbiological reviews.

The catabolite repressor/activator (Cra) protein of enteric bacteria

M. Saier, T. Ramseier, M. Saier, 1996, Journal of bacteriology.

Altered transcriptional patterns affecting several metabolic pathways in strains of Salmonella typhimurium which overexpress the fructose regulon

M H Saier, D. Feldheim, M. Saier, 1989, Journal of bacteriology.

Catabolite repression and inducer control in Gram-positive bacteria.

I. Paulsen, M. Saier, J. Deutscher, 1996, Microbiology.

Protein phosphorylation and regulation of carbon metabolism in gram-negative versus gram-positive bacteria.

M. Saier, J. Deutscher, J. Reizer, 1995, Trends in biochemical sciences.

Phylogenetic relationships among bacteriorhodopsins.

M H Saier, M. Saier, G Kuan, 1994, Research in microbiology.

The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations.

M H Saier, I. Paulsen, M. Saier, 2000, Microbiology.

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport.

M. Saier, M. Marger, M. D. Marger, 1993, Trends in biochemical sciences.

A bacterial model system for understanding multi-drug resistance.

I. Paulsen, M. Saier, A. Matin, 1997, Microbial drug resistance.

Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein.

Y Zhai, M H Saier, Douglas W. Smith, 2001, Biochimica et biophysica acta.

Sequence and evolution of the FruR protein of Salmonella typhimurium: a pleiotropic transcriptional regulatory protein possessing both activator and repressor functions which is homologous to the periplasmic ribose-binding protein.

M. Saier, E. Groisman, J. Tomich, 1991, Research in microbiology.

Regulation of the raffinose permease of Escherichia coli by the glucose-specific enzyme IIA of the phosphoenolpyruvate:sugar phosphotransferase system

M. Saier, F. Titgemeyer, R. Mason, 1994, Journal of bacteriology.

Corrected sequence of the mannitol (mtl) operon in Escherichia coli

W. Jiang, J. Tomich, W. Niehaus, 1990, Molecular microbiology.

Science, Innovation and the Future of Humanity

J. Trevors, M. Saier, Jr., M. Saier Jr., 2017, Journal of Molecular Microbiology and Biotechnology.

Structural and phylogenetic analysis of the MotA and MotB families of bacterial flagellar motor proteins.

C. C. Nguyen, M. Saier, 1996 .

Families of transmembrane transporters selective for amino acids and their derivatives.

M. Saier, M. Saier, 2000, Microbiology.

Catabolite repression resistance of gnt operon expression in Bacillus subtilis conferred by mutation of His-15, the site of phosphoenolpyruvate-dependent phosphorylation of the phosphocarrier protein HPr

M. Saier, W. Hillen, J. Deutscher, 1996, Journal of bacteriology.

Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis

M. Saier, J. Deutscher, A. Galinier, 1994, Journal of bacteriology.

Functional interactions between proteins of the phosphoenolpyruvate:sugar phosphotransferase systems of Bacillus subtilis and Escherichia coli.

M. Saier, J. Deutscher, L. Wu, 1992, The Journal of biological chemistry.

Multiple mechanisms controlling carbon metabolism in bacteria.

M. Saier, M. Saier, 1998, Biotechnology and bioengineering.

The mitochondrial carrier family of transport proteins: structural, functional, and evolutionary relationships.

M H Saier, M. Saier, J Kuan, 1993, Critical reviews in biochemistry and molecular biology.

The phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: properties, mechanism, and regulation.

M. Saier, J. Deutscher, J. Reizer, 1988, Critical reviews in microbiology.

A Novel Family of Ubiquitous Heavy Metal Ion Transport Proteins

I. Paulsen, J. M. Saier, M. Saier, 1997, The Journal of Membrane Biology.

Transport proteins in bacteria: common themes in their design.

M. Saier, H. Nikaido, M. Saier, 1992, Science.

In vitro binding of the pleiotropic transcriptional regulatory protein, FruR, to the fru, pps, ace, pts and icd operons of Escherichia coli and Salmonella typhimurium.

M H Saier, M. Saier, D. Nègre, 1993, Journal of molecular biology.

Structural and phylogenetic analysis of the MotA and MotB families of bacterial flagellar motor proteins.

M H Saier, M. Saier, C C Nguyen, 1996, Research in microbiology.

Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium

D. Feldheim, M. Saier, S. Sutrina, 1990, Journal of bacteriology.

The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases.

K. H. Kalk, M. Saier, G. Robillard, 1997, Structure.

Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-A resolution.

M H Saier, M. Saier, O. Herzberg, 1991, Biochemistry.

Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.

M. Hofnung, W. Saurin, M. Saier, 1995, Research in microbiology.

Evidence for the evolutionary relatedness of the proteins of the bacterial phosphoenolpyruvate:Sugar phosphotransferase system

M. Saier, Catherine A. Lee, E. Waygood, 1985, Journal of cellular biochemistry.

Enzyme I(Ntr) from Escherichia coli. A novel enzyme of the phosphoenolpyruvate-dependent phosphotransferase system exhibiting strict specificity for its phosphoryl acceptor, NPr.

M H Saier, I. Paulsen, M. Saier, 1999, The Journal of biological chemistry.

Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria.

M H Saier, I. Paulsen, M. Saier, 1997, Microbiology.

Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.

M H Saier, M. Saier, M. Arnaud, 1999, Microbiology.

New Glycoprotein-Associated Amino Acid Transporters

I. Paulsen, D. Jack, F. Verrey, 1999, The Journal of Membrane Biology.

Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions.

M H Saier, M. Saier, T B Cao, 2001, Microbiology.

Proposed uniform nomenclature for the proteins and protein domains of the bacterial phosphoenolpyruvate: sugar phosphotransferase system

M. Saier, J. Reizer, M. Saier, 1992, Journal of bacteriology.

Environment-directed activation of the Escherichia coliflhDC operon by transposons.

M. Saier, Zhongge Zhang, M. Z. Humayun, 2017, Microbiology.

Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella.

A. Pugsley, Christopher R Peabody, D. Vidal-Ingigliardi, 2003, Microbiology.

Climate Change, 2007

M. Saier, M. Saier, Milton H. Saier, 2007 .

The complete phosphotransferase system in Escherichia coli.

M H Saier, J. Edwards, M. Saier, 2001, Journal of molecular microbiology and biotechnology.

Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria.

M. Saier, J. Reizer, A. Reizer, 1994, Microbiology.

Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella.

M. Saier, M. Yen, A. Pugsley, 2003, Microbiology.

Modular assembly of voltage-gated channel proteins: a sequence analysis and phylogenetic study.

M. Saier, M. Montal, R. Nelson, 1999, Journal of molecular microbiology and biotechnology.

A novel ubiquitous family of putative efflux transporters.

M. Saier, K. Harley, M. Saier, 2000, Journal of molecular microbiology and biotechnology.

The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators.

M. Saier, A. Bellmann, M. Vrljic, 1999, Journal of molecular microbiology and biotechnology.

Paralogous genes encoding transport proteins in microbial genomes.

I. Paulsen, M. Saier, M. Saier, 1999, Research in microbiology.

Sequence Analyses and Phylogenetic Characterization of the ZIP Family of Metal Ion Transport Proteins

M. Saier, D. Eide, M. Guerinot, 1998, The Journal of Membrane Biology.

The MIP family of integral membrane channel proteins: sequence comparisons, evolutionary relationships, reconstructed pathway of evolution, and proposed functional differentiation of the two repeated halves of the proteins.

M. Saier, J. Reizer, A. Reizer, 1993, Critical reviews in biochemistry and molecular biology.

Catalytic activities associated with the enzymes II of the bacterial phosphotransferase system.

M. Saier, M. Saier, 1980, Journal of supramolecular structure.

Two novel families of bacterial membrane proteins concerned with nodulation, cell division and transport

M. Saier, J. Reizer, A. Reizer, 1994, Molecular microbiology.

Analysis of a cis-active sequence mediating catabolite repression in gram-positive bacteria.

M. Saier, W. Hillen, C. Hueck, 1994, Research in microbiology.

The mannitol repressor (MtlR) of Escherichia coli

M. Saier, R. Figge, T. Ramseier, 1994, Journal of bacteriology.

Carbohydrate transport in bacteria

M. Saier, J. Keats, A. Apperson, 1980 .

Structural and evolutionary relationships between two families of bacterial extracytoplasmic chaperone proteins which function cooperatively in fimbrial assembly.

M. Saier, M. van Rosmalen, M. Saier, 1993, Research in microbiology.

The amino acid/auxin:proton symport permease family.

D. W. Smith, M. Saier, D. Jack, 1999, Biochimica et biophysica acta.

Phylogenetic analyses of the constituents of Type III protein secretion systems.

M H Saier, I. Paulsen, M. Saier, 2000, Journal of molecular microbiology and biotechnology.

Regulation of the glucose:H+ symporter by metabolite-activated ATP-dependent phosphorylation of HPr in Lactobacillus brevis

J. W. Neal, J. Neal, M. Saier, 1994, Journal of bacteriology.

Genetic analyses of the mannitol permease of Escherichia coli: isolation and characterization of a transport-deficient mutant which retains phosphorylation activity

M. Saier, M. Yamada, J. Desai, 1988, Journal of bacteriology.

Cyclic AMP-independent catabolite repression in bacteria.

M H Saier, M. Saier, M. Saier, 1996, FEMS microbiology letters.

A novel family of channel-forming, autotransporting, bacterial virulence factors.

M. Saier, M. Saier, B. J. Loveless, 1997, Molecular membrane biology.

Characterization of chemically and virally transformed variants of Madin‐Darby canine kidney (MDCK) epithelial cells

M. Saier, P. Boerner, H. U, 1985, Journal of cellular physiology.

A web-based program (WHAT) for the simultaneous prediction of hydropathy, amphipathicity, secondary structure and transmembrane topology for a single protein sequence.

Y Zhai, M H Saier, M. Saier, 2001, Journal of molecular microbiology and biotechnology.

A web-based program for the prediction of average hydropathy, average amphipathicity and average similarity of multiply aligned homologous proteins.

M H Saier, Y Zhai, M. Saier, 2001, Journal of molecular microbiology and biotechnology.

The putative Na+/H+ antiporter (NapA) of Enterococcus hirae is homologous to the putative K+/H+ antiporter (KefC) of Escherichia coli.

M. Saier, J. Reizer, A. Reizer, 1992, FEMS microbiology letters.