Chang Wang

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT.

Xiaowu Dong, Jia Li, Tao Liu, 2022, Journal of medicinal chemistry.

Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia

Jianmin Yang, Jia Li, Yubing Han, 2022, Leukemia.

Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia

Jianmin Yang, Tao Wang, Minmin Liu, 2023, Nature Communications.

Discovery of quinazolin-4(3H)-one derivatives as novel AChE inhibitors with anti-inflammatory activities.

Yan Huang, Yanfeng Sun, C. Xue, 2023, European journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of 2‐Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors

T. Liu, Minjie Deng, Jia Li, 2023, ChemMedChem.

Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities.

T. Liu, Jia Li, Peipei Wang, 2023, Journal of medicinal chemistry.