Mark E. B. Smith

发表

Accurate Whole Human Genome Sequencing using Reversible Terminator Chemistry

Nancy F. Hansen, Lisa J. Murray, Phillip J. Black, 2008, Nature.

A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine† †Electronic supplementary information (ESI) available: LC-MS, ES-MS and deconvoluted spectra for all reactions with proteins described herein, and 1H and 13C NMR spectra for all small molecule construc

Mark E. B. Smith, S. Caddick, J. Baker, 2015, Organic & biomolecular chemistry.

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

James R. Baker, Gabriel Waksman, Mark E. B. Smith, 2010, Journal of the American Chemical Society.

Reversible protein affinity-labelling using bromomaleimide-based reagents† †Electronic supplementary information (ESI) available: 1H and 13C spectra for all new and known compounds, and ES-MS spectra for all reactions with proteins described herein. See DOI: 10.1039/c3ob40239h Click here for additio

Richard J. Fitzmaurice, S. Caddick, J. Baker, 2013, Organic & biomolecular chemistry.

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis† †Electronic supplementary information (ESI) available: Full experimental details and characterisation. See DOI: 10.1039/c1cc11114k Click he

James R. Baker, Gabriel Waksman, Finn Werner, 2011, Chemical communications.

Homogeneous Bispecifics by Disulfide Bridging

Mark E. B. Smith, K. Chester, J. Baker, 2014, Bioconjugate chemistry.

Homogeneous Bispeci fi cs by Disul fi de Bridging

K. Chester, J. Baker, Enrique Miranda, 2014 .

Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging

James R. Baker, Antoine Maruani, Kerry A. Chester, 2014, Organic & biomolecular chemistry.

In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation

James R. Baker, Andrew Tinker, Mark E. B. Smith, 2011, Bioconjugate chemistry.

Transgenic Cavendish bananas with resistance to Fusarium wilt tropical race 4

K. Mengersen, P. Waterhouse, G. Kema, 2017, Nature Communications.

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

Enrique Miranda, Antoine Maruani, Mark E.B. Smith, 2015, Nature Communications.

Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics'

James R. Baker, John M. Ward, Kerry A. Chester, 2013, Scientific Reports.

Bromomaleimides: new reagents for the selective and reversible modification of cysteine.

Mark E. B. Smith, J. Baker, L. Tedaldi, 2009, Chemical communications.