J. W. Perthold

发表

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology.

N. Montserrat, L. Boon, L. Endler, 2022, eLife.

Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor

K. Zatloukal, C. Oostenbrink, J. Penninger, 2021, bioRxiv.

Designing Fcabs: well-expressed and stable high affinity antigen-binding Fc fragments

F. Rüker, M. Woisetschläger, G. Wozniak-Knopp, 2017, Protein engineering, design & selection : PEDS.

Simulation of Reversible Protein–Protein Binding and Calculation of Binding Free Energies Using Perturbed Distance Restraints

Chris Oostenbrink, Jan Walther Perthold, C. Oostenbrink, 2017, Journal of chemical theory and computation.

Charge-Changing Perturbations and Path Sampling via Classical Molecular Dynamic Simulations of Simple Guest–Host Systems

C. Oostenbrink, Christoph Öhlknecht, Bettina Lier, 2020, Journal of chemical theory and computation.

Toward Automated Free Energy Calculation with Accelerated Enveloping Distribution Sampling (A-EDS)

Chris Oostenbrink, Drazen Petrov, Jan Walther Perthold, 2020, J. Chem. Inf. Model..

Accelerated Enveloping Distribution Sampling: Enabling Sampling of Multiple End States while Preserving Local Energy Minima.

Chris Oostenbrink, Jan Walther Perthold, C. Oostenbrink, 2018, The journal of physical chemistry. B.

An antibody with Fab-constant domains exchanged for a pair of CH3 domains

F. Rüker, Stefan Becker, G. Wozniak-Knopp, 2018, PloS one.

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

N. Montserrat, L. Boon, L. Endler, 2021, bioRxiv.

GroScore: Accurate Scoring of Protein-Protein Binding Poses Using Explicit-Solvent Free-Energy Calculations

Chris Oostenbrink, Jan Walther Perthold, C. Oostenbrink, 2019, J. Chem. Inf. Model..

Guidelines for Free-Energy Calculations Involving Charge Changes

C. Oostenbrink, D. Petrov, Vytautas Gapsys, 2024, Journal of chemical theory and computation.