Julio Escribano

发表

Gene expression of the neurotrophic pigment epithelium-derived factor in the human ciliary epithelium. Synthesis and secretion into the aqueous humor.

J. Escribano, J. Ortego, S. Becerra, 1996, Investigative ophthalmology & visual science.

New perspectives in aqueous humor secretion and in glaucoma: The ciliary body as a multifunctional neuroendocrine gland

J. Escribano, M. Coca‐Prados, Julio Escribano, 2007, Progress in Retinal and Eye Research.

Differential gene expression in the human ciliary epithelium

M. Coca-Prados, J. Escribano, J. Ortego, 1999, Progress in Retinal and Eye Research.

Gene expression of proteases and protease inhibitors in the human ciliary epithelium and ODM-2 cells.

J. Escribano, J. Ortego, M. Coca‐Prados, 1997, Experimental eye research.

Treatment of human brucellosis with doxycycline and gentamicin

J. Solera, J. Escribano, L. Sánchez, 1997, Antimicrobial agents and chemotherapy.

Pigment epithelium–derived factor is a niche signal for neural stem cell renewal

I. Fariñas, P. Sánchez, Celia Andreu-Agullo, 2006, Nature Neuroscience.

Current perspectives in Bietti crystalline dystrophy

G. García-García, M. Martínez-Rubio, Medina-Azahara Moya-Moya, 2019, Clinical ophthalmology.

CPAMD8 loss-of-function underlies non-dominant congenital glaucoma with variable anterior segment dysgenesis and abnormal extracellular matrix

J. Salazar, B. Rojas, A. Ramírez, 2020, Human Genetics.

Rare FOXC1 variants in congenital glaucoma: identification of translation regulatory sequences

J. García-Feijóo, J. Escribano, C. Mendez-Hernandez, 2015, European Journal of Human Genetics.

Hypo- and Hypermorphic FOXC1 Mutations in Dominant Glaucoma: Transactivation and Phenotypic Variability

J. García-Feijóo, C. Ayuso, F. Blanco-Kelly, 2015, PLoS ONE.

Role of FOXC2 and PITX2 rare variants associated with mild functional alterations as modifier factors in congenital glaucoma

J. García-Feijóo, J. Escribano, C. Mendez-Hernandez, 2019, PloS one.

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer

A. S. Salinas-Sánchez, J. M. Giménez-Bachs, L. Serrano-Oviedo, 2011, BJU international.

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development

M. Gut, M. Cortón, J. García-Feijóo, 2017, Scientific Reports.

Goniodysgenesis variability and activity of CYP1B1 genotypes in primary congenital glaucoma

J. Salazar, R. de Hoz, B. Rojas, 2017, PloS one.

Null CYP1B1 genotypes in primary congenital and nondominant juvenile glaucoma.

J. García-Feijóo, J. Escribano, J. Martinez-de-la-Casa, 2013, Ophthalmology.

Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

J. Escribano, J. Aroca-Aguilar, Juan-Manuel Bonet-Fernández, 2021, International journal of molecular sciences.

Clinical Variability of Primary Congenital Glaucoma in a Spanish Family With Cyp1b1 Gene Mutations

J. García-Feijóo, J. Escribano, J. Martinez-de-la-Casa, 2015, Journal of glaucoma.

CYP1B1 mutations in Spanish patients with primary congenital glaucoma: phenotypic and functional variability

Carmen Ayuso, J. García-Feijóo, C. Ayuso, 2009, Molecular vision.

Comparison of three different PCR methods for detection of Brucella spp in human blood samples.

J. Solera, J. Escribano, E. Navarro, 2002, FEMS immunology and medical microbiology.

PCR Assay for Diagnosis of Human Brucellosis

J. Solera, J. Escribano, E. Navarro, 1999, Journal of Clinical Microbiology.

Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): an experimental study in the rat.

H. Riese, J. Escribano, J. Fernández, 1999, Nutrition and cancer.

Knockout of myoc Provides Evidence for the Role of Myocilin in Zebrafish Sex Determination Associated with Wnt Signalling Downregulation

J. Aroca-Aguilar, Juan-Manuel Bonet-Fernández, Susana Alexandre-Moreno, 2021, Biology.

Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation

J. Aroca-Aguilar, Juan-Manuel Bonet-Fernández, Susana Alexandre-Moreno, 2020, bioRxiv.

Heterozygous CYP1B1 gene mutations in Spanish patients with primary open-angle glaucoma.

J. Escribano, J. Aroca-Aguilar, C. Blanco-Marchite, 2006, Molecular vision.

Role of GUCA1C in Primary Congenital Glaucoma and in the Retina: Functional Evaluation in Zebrafish

J. García-Feijóo, N. Cuenca, J. Escribano, 2020, Genes.

Functional analysis of CYP1B1 mutations and association of heterozygous hypomorphic alleles with primary open‐angle glaucoma

J. Escribano, C. Blanco-Marchite, María-Pilar López-Garrido, 2010, Clinical genetics.

Identification of a Lipase-linked Cell Membrane Receptor for Pigment Epithelium-derived Factor*

Raul Heredia, Jorge Laborda, Christina Meyer, 2006, Journal of Biological Chemistry.

Role of CYP1B1 gene polymorphisms in bladder cancer susceptibility.

A. S. Salinas-Sánchez, J. M. Giménez-Bachs, M. J. Donate-Moreno, 2012, The Journal of urology.

Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye

M. Coca-Prados, J. Jaroszewski, W. Huang, 2000, Ophthalmic genetics.

RNA and protein expression analysis of HLA‐DQB1*03:01:01:21Q allele: A null allele renamed as HLA‐DQB1*03:01:01:21N

J. Aroca-Aguilar, Mar Luis-Hidalgo, J. Ontañon, 2022, HLA.

Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro.

G. Alonso, M. Coca-Prados, J. Escribano, 1996, Cancer letters.

R124C and R555W TGFBI mutations in Spanish families with autosomal-dominant corneal dystrophies.

J. Escribano, C. Blanco-Marchite, E. López-Sánchez, 2007, Molecular vision.

cDNA from human ocular ciliary epithelium homologous to βig‐h3 is preferentially expressed as an extracellular protein in the corneal epithelium

J. Crabb, J. Escribano, N. Hernando, 1994, Journal of cellular physiology.

LOXL1 gene variants and their association with pseudoexfoliation glaucoma (XFG) in Spanish patients

L. Fernández-Vega, J. Escribano, Montserrat García, 2015, BMC Medical Genetics.

Heterozygous expression of myocilin glaucoma mutants increases secretion of the mutant forms and reduces extracellular processed myocilin

J. Aroca-Aguilar, M. Coca‐Prados, Francisco Martínez-Redondo, 2008, Molecular vision.

Sex steroid hormone metabolism takes place in human ocular cells

P. Vihko, Yugang Wang, J. Escribano, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Characterization of the Intracellular Proteolytic Cleavage of Myocilin and Identification of Calpain II as a Myocilin-processing Protease*

J. Aroca-Aguilar, M. Coca‐Prados, Francisco Martínez-Redondo, 2007, Journal of Biological Chemistry.

Myocilin Mutations Causing Glaucoma Inhibit the Intracellular Endoproteolytic Cleavage of Myocilin between Amino Acids Arg226 and Ile227*

J. Escribano, J. Aroca-Aguilar, M. Coca‐Prados, 2005, Journal of Biological Chemistry.

Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases.

W. Huang, J. Escribano, M. Coca‐Prados, 1999, Gene.

Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin

J. Escribano, J. Ortego, M. Coca‐Prados, 1997, FEBS letters.

Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins.

J. Escribano, J. Ortego, M. Coca‐Prados, 1995, Journal of biochemistry.

Angiotensin-converting enzyme (ACE) gene polymorphisms, serum ACE activity and blood pressure in a Spanish-Mediterranean population

C. Sánchis, J. Escribano, J. Fernández, 2000, Journal of Human Hypertension.

A glycoconjugate from corms of saffron plant (Crocus sativus L.) inhibits root growth and affects in vitro cell viability.

A. Piqueras, J. Fernández, J. Medina, 2000, Journal of experimental botany.

Production of a cytotoxic proteoglycan using callus culture of saffron corms (Crocus sativus L.).

M. Álvarez-Ortí, A. Rubio, J. Escribano, 1999, Journal of biotechnology.

Triterpenoid saponins from corms of Crocus sativus: Localization, extraction and characterization

G. Gerwig, J. Kamerling, Á. Rubio-Moraga, 2011 .

Development of cormogenic nodules and microcorms by tissue culture, a new tool for the multiplication and genetic improvement of saffron

J. Fernández, J. Escribano, A. Piqueras, 1999 .

Isolation and cytotoxic properties of a novel glycoconjugate from corms of saffron plant (Crocus sativus L.).

J. Escribano, J. Fernández, I. Rios, 1999, Biochimica et biophysica acta.

The cytolytic effect of a glycoconjugate extracted from corms of saffron plant (Crocus sativus) on human cell lines in culture.

M. Díaz-Guerra, H. Riese, J. Fernández, 2000, Planta medica.

In vitro activation of macrophages by a novel proteoglycan isolated from corms of Crocus sativus L.

M. Díaz-Guerra, H. Riese, D. García-Olmo, 1999, Cancer letters.

DEVELOPMENT AND GENE EXPRESSION IN SAFFRON CORMS

J. Pardo, M. Álvarez-Ortí, A. Rubio, 2004 .

Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications.

J. Escribano, J. Aroca-Aguilar, M. Coca‐Prados, 2011, Investigative ophthalmology & visual science.

Interaction of myocilin with the C-terminal region of hevin.

J. Aroca-Aguilar, M. Coca‐Prados, Sikha Ghosh, 2006, Biochemical and biophysical research communications.

Transgenic Overexpression of Myocilin Leads to Variable Ocular Anterior Segment and Retinal Alterations Associated with Extracellular Matrix Abnormalities in Adult Zebrafish

N. Cuenca, J. Escribano, J. Aroca-Aguilar, 2022, International journal of molecular sciences.

Functional role of proteolytic processing of recombinant myocilin in self-aggregation.

J. Escribano, J. Aroca-Aguilar, M. Coca‐Prados, 2010, Investigative ophthalmology & visual science.

Expression and purification of functional recombinant human pigment epithelium-derived factor (PEDF) secreted by the yeast Pichia pastoris.

H. Riese, J. Escribano, I. Segura, 2008, Journal of biotechnology.

Bioinformatics and reanalysis of subtracted expressed sequence tags from the human ciliary body: Identification of novel biological functions.

M. Coca‐Prados, Julio Escribano, 2002, Molecular vision.

Identification of a Neuropeptide and Neuropeptide‐Processing Enzymes in Aqueous Humor Confers Neuroendocrine Features to the Human Ocular Ciliary Epithelium

J. Crabb, J. Escribano, J. Ortego, 1996, Journal of neurochemistry.

Molecular and neurochemical substrates of the audiogenic seizure strains: The GASH:Sal model

D. E. López, J. Escribano, J. Aroca-Aguilar, 2017, Epilepsy & Behavior.

CFH polymorphisms in a Northern Spanish population with neovascular and dry forms of age‐related macular degeneration

L. Fernández-Vega, A. Nogacka, Beatriz Fernández-Vega, 2015, Acta ophthalmologica.

Primary congenital glaucoma caused by the homozygous F261L CYP1B1 mutation and paternal isodisomy of chromosome 2

J. Escribano, María-Pilar López-Garrido, E. Campos-Mollo, 2009, Clinical genetics.

GSTT1, GSTM1, and CYP1B1 gene polymorphisms and susceptibility to sporadic renal cell cancer.

A. S. Salinas-Sánchez, J. M. Giménez-Bachs, M. J. Donate-Moreno, 2012, Urologic oncology.

Threonines at position 174 and 235 of the angiotensinogen polypeptide chain are related to familial history of hypertension in a Spanish-Mediterranean population

C. Sánchis, J. Escribano, J. Fernández, 2002, British journal of biomedical science.

Comparative proteomic study in serum of patients with primary open-angle glaucoma and pseudoexfoliation glaucoma.

L. Fernández-Vega, J. Escribano, Montserrat García, 2014, Journal of proteomics.

Genotype–Phenotype Analysis of Bietti Crystalline Dystrophy in a Family with the CYP4V2 Ile111Thr Mutation

G. García-García, M. Martínez-Rubio, Medina-Azahara Moya-Moya, 2013, Cornea.

Identification of novel CYP4V2 genotypes associated with Bietti crystalline dystrophy and atypical anterior segment phenotypes in Spanish patients

J. Pérez-Santonja, G. García-García, M. Martínez-Rubio, 2018, Acta ophthalmologica.

Recent patents and developments in glaucoma biomarkers.

R. Herrero-Vanrell, X. Gasull, J. García-Feijóo, 2012, Recent Patents on Endocrine Metabolic & Immune Drug Discovery.

Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration

J. Escribano, L. Fernández-Vega Cueto, Beatriz Fernández-Vega, 2017, Ophthalmic genetics.

WDR36 and P53 gene variants and susceptibility to primary open-angle glaucoma: analysis of gene-gene interactions.

L. Fernández-Vega, M. Coca-Prados, J. García-Feijóo, 2011, Investigative ophthalmology & visual science.

Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy.

D. E. López, S. Llorens, E. Nava, 2012, Life sciences.

Implications of mismatch repair genes hMLH1 and hMSH2 in patients with sporadic renal cell carcinoma

A. S. Salinas-Sánchez, J. M. Giménez-Bachs, J. Escribano, 2008, BJU international.

Identification of myocilin as a blood plasma protein and analysis of its role in leukocyte adhesion to endothelial cell monolayers

J. Escribano, J. Aroca-Aguilar, M. Coca‐Prados, 2018, PloS one.

Bicarbonate-Dependent Secretion and Proteolytic Processing of Recombinant Myocilin

J. Pintor, J. Escribano, Alba Martín-Gil, 2013, PloS one.

Role of MYOC and OPTN sequence variations in Spanish patients with Primary Open-Angle Glaucoma

J. Escribano, María-Pilar López-Garrido, Francisco López-Martínez, 2007, Molecular vision.

Heterozygous CYP 1 B 1 gene mutations in Spanish patients with primary open-angle glaucoma

J. Escribano, J. Aroca-Aguilar, C. Blanco-Marchite, 2006 .

Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample.

C. Sánchis, E. Martínez, L. Carrión, 2007, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Co‐inheritance of HNF1a and GCK mutations in a family with maturity‐onset diabetes of the young (MODY): implications for genetic testing

J. Escribano, P. Giralt, S. Herranz-Antolín, 2013, Clinical endocrinology.

Isolation of cDNA clones encoding the 80-kd subunit protein of the human autoantigen Ku (p70/p80) by antisera raised against ciliary processes of human eye donors.

M. Coca‐Prados, Julio Escribano, T. J. Hong, 1994, Investigative ophthalmology & visual science.

Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration

L. Fernández-Vega Cueto, Beatriz Fernández-Vega, Montserrat García, 2017, Ophthalmic Genetics.

Role of CYP1B1 gene polymorphisms in bladder cancer susceptibility.

A. S. Salinas-Sánchez, J. M. Giménez-Bachs, M. J. Donate-Moreno, 2012, Journal of Urology.

Null CYP1B1 genotypes in primary congenital and nondominant juvenile glaucoma.

J. García-Feijóo, María-Pilar López-Garrido, Cristina Medina-Trillo, 2013, Ophthalmology.

Seizures regulate the cation-Cl− cotransporter NKCC1 in a hamster model of epilepsy: implications for GABA neurotransmission

D. E. López, P. Tranque, J. Aroca-Aguilar, 2023, Frontiers in Neurology.

MYOC gene mutations in Spanish patients with autosomal dominant primary open-angle glaucoma: a founder effect in southeast Spain.

J. Escribano, María-Pilar López-Garrido, Francisco López-Martínez, 2007, Molecular vision.

Functional characterization of eight rare missense CYP1B1 variants involved in congenital glaucoma and their association with null genotypes

J. Escribano, J. Aroca-Aguilar, Juan-Manuel Bonet-Fernández, 2016, Acta ophthalmologica.

Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy.

D. E. López, S. Llorens, E. Nava, 2012, Life Science.