J. Ptacek

发表

Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.

J. Vávra, C. Bařinka, D. Ferraris, 2016, Journal of medicinal chemistry.

Rational Design of Suprastat, a Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.

G. M. Ferreira, Guiping Zhang, J. Stránský, 2020, Journal of medicinal chemistry.

The calcium‐binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity

J. Konvalinka, C. Bařinka, Barbora Havlínová, 2018, Protein science : a publication of the Protein Society.

Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells

A. Kozikowski, C. Bařinka, P. Majer, 2023, International journal of molecular sciences.

Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer

X. Zou, P. Giangrande, Shi-jie Chen, 2020, Nucleic acids research.

Structural and biochemical characterization of the folyl‐poly‐γ‐l‐glutamate hydrolyzing activity of human glutamate carboxypeptidase II

J. Konvalinka, J. Lubkowski, C. Bařinka, 2014, The FEBS journal.

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).

A. Skerra, C. Bařinka, V. Morath, 2016, Protein engineering, design & selection : PEDS.

Glutamate carboxypeptidase II: an overview of structural studies and their importance for structure-based drug design and deciphering the reaction mechanism of the enzyme.

C. Bařinka, J. Ptáček, J. Pavlíček, 2012, Current medicinal chemistry.

Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6)

M. Schutkowski, A. Kozikowski, L. Rulíšek, 2023, ACS chemical biology.

Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesis and structural characterization.

JaeHyung Koo, Kiwon Ok, Youngjoo Byun, 2015, Bioorganic & medicinal chemistry letters.

Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II.

M. Pomper, J. Lubkowski, J. Černý, 2014, Bioorganic & medicinal chemistry letters.

Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen

C. Bařinka, Z. Nováková, Barbora Havlínová, 2023, ACS Pharmacology & Translational Science.