Alexander Hoepping

First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (−)-[18F]Flubatine

Gudrun Wagenknecht, Marianne Patt, Solveig Tiepolt, 2015, NeuroImage.

Internal Dose Assessment of (–)-18F-Flubatine, Comparing Animal Model Datasets of Mice and Piglets with First-in-Human Results

Marianne Patt, Osama Sabri, Jörg Steinbach, 2014, The Journal of Nuclear Medicine.

PET Imaging of Cerebral Nicotinic Acetylcholine Receptors (nAChRs) in Early Alzheimer’s Disease (AD) Assessed with the New Radioligand (–)-[18F]Norchloro-Fluoro-Homoepibatidine ((–)-[18F]Flubatine)

Gudrun Wagenknecht, Osama Sabri, Jörg Steinbach, 2012 .

Radiosynthesis of racemic and enantiomerically pure (-)-[18F]flubatine--a promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors.

Paul Cumming, Osama Sabri, Steffen Fischer, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application.

Gudrun Wagenknecht, Marianne Patt, Osama Sabri, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.

Paul Cumming, Marianne Patt, Osama Sabri, 2014, Bioorganic & medicinal chemistry.

Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (-)-[(18)F]Flubatine in humans.

Gudrun Wagenknecht, Swen Hesse, Marianne Patt, 2014, Nuclear medicine and biology.