Bert Vogelstein

发表

Reconstructing robust phylogenies of metastatic cancers

Martin A. Nowak, Krishnendu Chatterjee, Johannes G. Reiter, 2015 .

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

Young Joon Ahn, Elliot K. Fishman, Yuxuan Wang, 2017, J. Am. Medical Informatics Assoc..

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

Martin A. Nowak, Bartlomiej Waclaw, Ivana Bozic, 2015, Nature.

Genetic Progression and the Waiting Time to Cancer

Martin A. Nowak, Arne Traulsen, Niko Beerenwinkel, 2007, PLoS Comput. Biol..

Musings on the theory that variation in cancer risk among tissues can be explained by the number of divisions of normal stem cells

Bert Vogelstein, Cristian Tomasetti, B. Vogelstein, 2015, 1501.05035.

Allelic Variation in Human Gene Expression

Bert Vogelstein, K. Kinzler, B. Vogelstein, 2002, Science.

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

Michael A. Choti, Yuchen Jiao, Victor E. Velculescu, 2011, Science.

Tumour suppression: Disruption of HAUSP gene stabilizes p53

Carlo Rago, Bert Vogelstein, Kenneth W. Kinzler, 2004, Nature.

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.

Yuchen Jiao, Yuxuan Wang, Bert Vogelstein, 2012, Cancer discovery.

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Giovanni Parmigiani, Amanda Blackford, Christine A Iacobuzio-Donahue, 2009, Clinical Cancer Research.

Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia

John D. Minna, John M. Maris, Victor E. Velculescu, 2004, Cancer Research.

Digital karyotyping

Michael R. Speicher, Tian-Li Wang, Victor E. Velculescu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Reconstructing metastatic seeding patterns of human cancers

Krishnendu Chatterjee, Martin A Nowak, Christine A Iacobuzio-Donahue, 2017, Nature Communications.

Activation of diverse signaling pathways by oncogenic PIK3CA mutations

Akhilesh Pandey, Xinyan Wu, Heng Zhu, 2014, Nature Communications.

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

Scott E. Kern, Bert Vogelstein, Stephan A. Hahn, 1996, Nature Genetics.

The role of chromosomal instability in tumor initiation

Martin A. Nowak, Natalia L. Komarova, Anirvan Sengupta, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Prevalence of somatic alterations in the colorectal cancer cell genome

Giovanni Parmigiani, Tian-Li Wang, Carlo Rago, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers

Giovanni Parmigiani, Bert Vogelstein, Sanford Markowitz, 2003, Nature Reviews Cancer.

The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations

Bert Vogelstein, Kenneth W. Kinzler, Diana Mandelker, 2007, Science.

Mad-related genes in the human

Scott E. Kern, Bert Vogelstein, Kenneth W. Kinzler, 1996, Nature Genetics.

Remote loading of preencapsulated drugs into stealth liposomes

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 2014, Proceedings of the National Academy of Sciences.

A combination of molecular markers and clinical features improve the classification of pancreatic cysts.

Jin-Young Jang, Amanda Blackford, Mari Mino-Kenudson, 2015, Gastroenterology.

Cell-cycle arrest versus cell death in cancer therapy

Bert Vogelstein, K. Kinzler, B. Vogelstein, 1997, Nature Medicine.

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Giovanni Parmigiani, Amanda Blackford, Victor E. Velculescu, 2012, Nature Genetics.

The Structure of a Human p 110 a / p 85 a Complex Elucidates the Effects of Oncogenic PI 3 K a Mutations

L. Mario Amzel, Victor E. Velculescu, Bert Vogelstein, 2007 .

STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA

Giovanni Parmigiani, Bert Vogelstein, Kenneth W. Kinzler, 2007 .

Gatekeepers and caretakers

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 1997, Nature.

BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

Frank Diehl, Bert Vogelstein, Yiping He, 2006, Nature Methods.

Mutant PIK 3 CA promotes cell growth and invasion of human cancer cells

Carlo Rago, Victor E. Velculescu, Bert Vogelstein, 2005 .

The significance of unstable chromosomes in colorectal cancer

Martin A. Nowak, Bert Vogelstein, Christoph Lengauer, 2003, Nature Reviews Cancer.

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Tian-Li Wang, Kentaro Nakayama, Bert Vogelstein, 2010, Science.

Somatic mutations of the mitochondrial genome in human colorectal tumours

Bert Vogelstein, Kenneth W. Kinzler, Kornelia Polyak, 1998, Nature Genetics.

Structural comparisons of class I phosphoinositide 3-kinases

L. Mario Amzel, Bert Vogelstein, Diana Mandelker, 2008, Nature Reviews Cancer.

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Robin J. Leach, Paul S. Meltzer, Jean Weissenbach, 1993, Cell.

Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Comparative lesion sequencing provides insights into tumor evolution

Martin A. Nowak, Arne Traulsen, Niko Beerenwinkel, 2008, Proceedings of the National Academy of Sciences.

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

Gary L. Gallia, Yuchen Jiao, Yuxuan Wang, 2013, Oncotarget.

Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers"

Giovanni Parmigiani, Victor E. Velculescu, Bert Vogelstein, 2007, Science.

Inactivation of hCDC4 can cause chromosomal instability

Carlo Rago, Victor E. Velculescu, Bert Vogelstein, 2004, Nature.

DETECTION OF CIRCULATING TUMOR DNA IN EARLY AND LATE STAGE HUMAN MALIGNANCIES

Bert Vogelstein, Kenneth W. Kinzler, Brandon Luber, 2014 .

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

Michael A Choti, Bert Vogelstein, Timothy M Pawlik, 2011, Nature Genetics.

The role of companion diagnostics in the development and use of mutation-targeted cancer therapies

Bert Vogelstein, K. Kinzler, B. Vogelstein, 2006, Nature Biotechnology.

Conversion of diploidy to haploidy

James R. Eshleman, Bert Vogelstein, Kenneth W. Kinzler, 2000, Nature.

Isaac Kinde Endometrial Cancers Evaluation of DNA from the Papanicolaou Test to Detect Ovarian

James R. Eshleman, Yuxuan Wang, Bert Vogelstein, 2013 .

Genetic instability and darwinian selection in tumours

Bert Vogelstein, Kenneth W. Kinzler, Christoph Lengauer, 1999 .

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

Giovanni Parmigiani, Bert Vogelstein, Cristian Tomasetti, 2013, Proceedings of the National Academy of Sciences.

Combinatorial chemoprevention of intestinal neoplasia

Bert Vogelstein, Kenneth W. Kinzler, Allan Wissner, 2000, Nature Medicine.

Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer

Yuchen Jiao, Ami A. Shah, Bert Vogelstein, 2014, Science.

Mutational Analysis of the APC/β-Catenin/Tcf Pathway in Colorectal Cancer

Bert Vogelstein, Kenneth W. Kinzler, A. Sparks, 1998 .

Counting alleles reveals a connection between chromosome 18q loss and vascular invasion

Michael A. Choti, Steven N. Goodman, Wei Zhou, 2001, Nature Biotechnology.

Gene Targeting in Human Cells Without Isogenic DNA

John M. Sedivy, Bert Vogelstein, Howard L. Liber, 1999, Science.

ATM mutations in patients with hereditary pancreatic cancer.

Yuchen Jiao, Michele L Cote, Bert Vogelstein, 2012, Cancer discovery.

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations.

Bert Vogelstein, Sandra B Gabelli, Diana Mandelker, 2007, Science.

X-rays strike p53 again

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 1994, Nature.

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

Gary L. Gallia, Arthur P. Grollman, Tian-Li Wang, 2013, Proceedings of the National Academy of Sciences.

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Bert Vogelstein, Kenneth W. Kinzler, Jennifer A. Pietenpol, 1993, Nature.

Identification of microbial DNA in human cancer

Tian-Li Wang, Bert Vogelstein, C. Schaefer, 2009, BMC Medical Genomics.

CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling

Tong-Chuan He, Bert Vogelstein, Kornelia Polyak, 1999, Oncogene.

Structural basis of nSH2 regulation and lipid binding in PI3Kα

L. Mario Amzel, Philip E. Thompson, Bert Vogelstein, 2014, Oncotarget.

Detection and quantification of mutations in the plasma of patients with colorectal tumors.

Frank Diehl, Bert Vogelstein, Steven N Goodman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

APC mutations occur early during colorectal tumorigenesis

Bert Vogelstein, Kenneth W. Kinzler, Stanley R. Hamilton, 1992, Nature.

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

Alison P. Klein, James R. Eshleman, Giovanni Parmigiani, 2009, Science.

A Phosphatase Associated with Metastasis of Colorectal Cancer

Michael A. Choti, Carlo Rago, Victor E. Velculescu, 2001, Science.

Can chromosomal instability initiate tumorigenesis?

Martin A Nowak, Yoh Iwasa, Franziska Michor, 2005, Seminars in cancer biology.

Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria

Bert Vogelstein, Kenneth W. Kinzler, Chetan Bettegowda, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers.

Rainer Lehtonen, Bert Vogelstein, Jukka-Pekka Mecklin, 2005, Cancer research.

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

Yuchen Jiao, Jinyong Luo, Tong-Chuan He, 2014, Genes, chromosomes & cancer.

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

Bert Vogelstein, Kenneth W. Kinzler, Christoph Lengauer, 1996, Nature.

Characterization of the Yeast Transcriptome

Wei Zhou, Bert Vogelstein, Jacob V. Vogelstein, 1997, Cell.

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis

Victor E. Velculescu, Bert Vogelstein, Gloria M. Petersen, 2001, Nature Genetics.

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

Bert Vogelstein, Toby C. Cornish, Toby C Cornish, 2015, The New England journal of medicine.

The Path to Cancer --Three Strikes and You're Out.

Bert Vogelstein, K. Kinzler, B. Vogelstein, 2015, The New England journal of medicine.

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Hans Clevers, Nick Barker, Bert Vogelstein, 1997, Science.

The Temporal Order of Genetic and Pathway Alterations in Tumorigenesis

Nicholas Eriksson, Niko Beerenwinkel, Bert Vogelstein, 2011, PloS one.

p53 function and dysfunction

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 1992, Cell.

Hypermutability and mismatch repair deficiency in RER+ tumor cells

Bert Vogelstein, Kenneth W. Kinzler, Paul Modrich, 1993, Cell.

The Predictive Capacity of Personal Genome Sequencing

Giovanni Parmigiani, Bert Vogelstein, Joshua T Vogelstein, 2012, Science Translational Medicine.

Bacteriolytic therapy can generate a potent immune response against experimental tumors.

Bert Vogelstein, Mitsuaki Tatsumi, Richard L Wahl, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

Akhilesh Pandey, Christine A Iacobuzio-Donahue, Anthony Gacita, 2015, Genome research.

Patient-oriented gene set analysis for cancer mutation data

Giovanni Parmigiani, Bert Vogelstein, Simina M Boca, 2010, Genome Biology.

Securin Is Required for Chromosomal Stability in Human Cells

Michael R. Speicher, Bert Vogelstein, Kenneth W. Kinzler, 2001, Cell.

Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

Carlo Rago, Bert Vogelstein, Yardena Samuels, 2005, Cancer cell.

Application of Deep Learning to Pancreatic Cancer Detection: Lessons Learned From Our Initial Experience.

Yan Wang, Yingda Xia, Qihang Yu, 2019, Journal of the American College of Radiology : JACR.

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

Bert Vogelstein, Christoph Lengauer, A. Feinberg, 2002, Nature.

Mutations of mitotic checkpoint genes in human cancers

Bert Vogelstein, Kenneth W. Kinzler, Christoph Lengauer, 1998, Nature.

BEAMing up for detection and quantification of rare sequence variants

Frank Diehl, Bert Vogelstein, Meng Li, 2006, Nature Methods.

Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

Yuchen Jiao, Bert Vogelstein, Chetan Bettegowda, 2011, Science.

Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design.

Bert Vogelstein, Sandra B Gabelli, Michelle S. Miller, 2017, Bioorganic & medicinal chemistry.

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

Arthur P. Grollman, Bert Vogelstein, Kenneth W. Kinzler, 2016, Proceedings of the National Academy of Sciences.

Evolutionary dynamics of cancer in response to targeted combination therapy

Krishnendu Chatterjee, Martin A Nowak, Benjamin Allen, 2013, eLife.

A Bacterial Protein Enhances the Release and Efficacy of Liposomal Cancer Drugs

Xin Huang, Bert Vogelstein, Chetan Bettegowda, 2006, Science.

Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers

Giovanni Parmigiani, Bert Vogelstein, Kishore Guda, 2009, Proceedings of the National Academy of Sciences.

Noninvasive imaging of infection after treatment with tumor‐homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI

Bert Vogelstein, Chetan Bettegowda, Guanshu Liu, 2013, Magnetic resonance in medicine.

Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

Robert S. Benjamin, Ravi Murthy, Bert Vogelstein, 2014, Science Translational Medicine.

Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers

Giovanni Parmigiani, Tian-Li Wang, Brock A. Peters, 2004, Science.

Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types

Meng Li, Christine A Iacobuzio-Donahue, Bert Vogelstein, 2011, Human mutation.

The GLI gene is a member of the Kruppel family of zinc finger proteins

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 1988, Nature.

Assessing aneuploidy with repetitive element sequencing

Tian-Li Wang, Rachel Karchin, Robert E. Schoen, 2019, Proceedings of the National Academy of Sciences.