Nikolaos Lougiakis

发表

Design and synthesis of novel 7-aminosubstituted pyrido[2,3-b]pyrazines exhibiting anti-breast cancer activity.

V. Psycharis, C. Raptopoulou, O. Argyros, 2017, European journal of medicinal chemistry.

New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships.

D. Kletsas, H. Pratsinis, N. Lougiakis, 2021, European journal of medicinal chemistry.

Robust, universal biomarker assay to detect senescent cells in biological specimens

Dimitris Kletsas, Jiri Bartek, Manuel Serrano, 2016, Aging cell.

Novel nucleoside analogues targeting HCV replication through an NS5A‐dependent inhibition mechanism

R. Bartenschlager, Vanesa Madan, P. Marakos, 2017, Chemical biology & drug design.

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

R. Tenta, N. Lougiakis, P. Marakos, 2021, Molecules.

Design and synthesis of new substituted pyrazolopyridines with potent antiproliferative activity.

A. Skaltsounis, R. Tenta, P. Marakos, 2020, Medicinal chemistry (Shariqah (United Arab Emirates)).

SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors

M. Lahtela-Kakkonen, K. Nikolić, N. Djoković, 2023, Pharmaceuticals.

Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors

C. Vorgias, A. Papapetropoulos, E. Mikros, 2020, Molecules.

Immunotherapy Combined with Metronomic Dosing: An Effective Approach for the Treatment of NSCLC

T. Karampelas, C. Tamvakopoulos, N. Lougiakis, 2021, Cancers.

Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues

G. Andrei, R. Snoeck, N. Lougiakis, 2020, Molecules.

Novel pyrazolopyridine derivatives as potential angiogenesis inhibitors: Synthesis, biological evaluation and transcriptome-based mechanistic analysis.

A. Chatziioannou, F. Kolisis, O. Papadodima, 2016, European journal of medicinal chemistry.

Pharmacological postconditioning of the rabbit heart with non‐selective, A1, A2A and A3 adenosine receptor agonists

N. Dagres, I. Andreadou, A. Zoga, 2014, The Journal of pharmacy and pharmacology.

Design and synthesis of new C-nucleosides as potential adenosine deaminase inhibitors

E. Mikros, T. Nomikos, V. Myrianthopoulos, 2010 .

Ranolazine triggers pharmacological preconditioning and postconditioning in anesthetized rabbits through activation of RISK pathway.

N. Dagres, I. Andreadou, P. Efentakis, 2016, European journal of pharmacology.

NMR study of 5‐substituted pyrazolo[3,4‐c]pyridine derivatives

E. Mikros, R. Marek, Orestis Tsikouris, 2008, Magnetic resonance in chemistry : MRC.

Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.

G. Ladds, A. Kolocouris, Kerry Barkan, 2022, Journal of medicinal chemistry.

Novel Pyrazolo[3,4-c]pyridine Antagonists with Nanomolar affinity for A1 / A3 Adenosine Receptors: Binding Kinetics and Exploration of their Binding Profile Using Mutagenesis Experiments, MD simulations and TI/MD calculations

G. Ladds, A. Kolocouris, Kerry Barkan, 2021 .

Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides.

J. Balzarini, P. Marakos, N. Pouli, 2008, Chemical & pharmaceutical bulletin.

Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.

A. Papapetropoulos, I. Andreadou, P. Efentakis, 2016, Journal of medicinal chemistry.

Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer

S. Baritaki, R. Tenta, P. Marakos, 2023, Pharmaceutics.

Design, synthesis and cytotoxic activity evaluation of new aminosubstituted benzofurans.

O. Tsitsilonis, P. Samara, P. Marakos, 2014, Medicinal chemistry (Shariqah (United Arab Emirates)).

Discovery of a High Affinity Adenosine A1/A3 Receptor Antagonist with a Novel 7-Amino-pyrazolo[3,4-d]pyridazine Scaffold

G. Ladds, A. Kolocouris, Kerry Barkan, 2022, ACS medicinal chemistry letters.

Design, synthesis and anti-HBV activity evaluation of new substituted imidazo[4,5-b]pyridines.

N. Lougiakis, P. Marakos, N. Pouli, 2020, Bioorganic chemistry.

Nemanja Djokovic

M. Lahtela-Kakkonen, N. Djoković, Minna Rahnasto-Rilla, 2022 .

A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.

V. Gorgoulis, A. Kotsinas, K. Evangelou, 2023, Molecular cell.

Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.

G. Lambrinidis, P. Efentakis, E. Mikros, 2023, Journal of medicinal chemistry.