Koen V D Sanden

A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity

Ilya J. Finkelstein, Stephen K. Jones, M. Depken, 2022, Nature Communications.

A kinetic model improves off-target predictions and reveals the physical basis of SpCas9 fidelity

Ilya J. Finkelstein, Stephen K. Jones, Misha Klein, 2020, bioRxiv.