Alexey Silakov

发表

A 2.8 Å Fe-Fe separation in the Fe2(III/IV) intermediate, X, from Escherichia coli ribonucleotide reductase.

C. Krebs, J. Bollinger, Michael T. Green, 2013, Journal of the American Chemical Society.

Importance of the Protein Framework for Catalytic Activity of [FeFe]-Hydrogenases

W. Lubitz, F. Armstrong, T. Happe, 2011, The Journal of Biological Chemistry.

Catalytic Activity of [ FeFe ]-Hydrogenases Importance of the Protein Framework for Molecular Biophysics :

W. Lubitz, F. Armstrong, T. Happe, 2011 .

(14)N HYSCORE investigation of the H-cluster of [FeFe] hydrogenase: evidence for a nitrogen in the dithiol bridge.

B. Wenk, W. Lubitz, A. Silakov, 2009, Physical chemistry chemical physics : PCCP.

An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.

N. Yennawar, O. Esakova, A. Silakov, 2019, Journal of the American Chemical Society.

Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid.

N. Yennawar, O. Esakova, A. Silakov, 2016, Journal of the American Chemical Society.

Ferredoxins as interchangeable redox components in support of MiaB, a radical S‐adenosylmethionine methylthiotransferase

S. Elliott, S. Booker, A. Arcinas, 2019, Protein science : a publication of the Protein Society.

Identification and characterization of the "super-reduced" state of the H-cluster in [FeFe] hydrogenase: a new building block for the catalytic cycle?

W. Lubitz, A. Adamska, E. Reijerse, 2012, Angewandte Chemie.

Investigation of the unusual ability of the [FeFe] Hydrogenase from Clostridium beijerinkii to access an O2-protected state.

Jonathan L Tirsch, Pa Corrigan, Alexey Silakov, 2020, Journal of the American Chemical Society.

Magnetic Properties of [FeFe]-Hydrogenases: A Theoretical Investigation Based on Extended QM and QM/MM Models of the H-Cluster and Its Surroundings

U. Ryde, W. Lubitz, M. Bruschi, 2011 .

Unraveling the Electronic Properties of the Photoinduced States of the H‐Cluster in the [FeFe] Hydrogenase from D. desulfuricans

W. Lubitz, E. Reijerse, A. Silakov, 2011 .

Spin distribution of the H-cluster in the Hox–CO state of the [FeFe] hydrogenase from Desulfovibrio desulfuricans: HYSCORE and ENDOR study of 14N and 13C nuclear interactions

B. Wenk, W. Lubitz, A. Silakov, 2009, JBIC Journal of Biological Inorganic Chemistry.

Optimized over-expression of [FeFe] hydrogenases with high specific activity in Clostridium acetobutylicum

T. Happe, A. Silakov, P. Soucaille, 2008 .

Isolation and first EPR characterization of the [FeFe]-hydrogenases from green algae.

W. Lubitz, E. Reijerse, T. Happe, 2008, Biochimica et biophysica acta.

The electronic structure of the H-cluster in the [FeFe]-hydrogenase from Desulfovibrio desulfuricans: a Q-band 57Fe-ENDOR and HYSCORE study.

W. Lubitz, E. Hatchikian, A. Silakov, 2007, Journal of the American Chemical Society.

Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical

Benjamin D. Allen, R. Griffin, C. Krebs, 2018, Proceedings of the National Academy of Sciences.

Iron(IV)hydroxide pKa and the Role of Thiolate Ligation in C–H Bond Activation by Cytochrome P450

Michael T. Green, Rachel K. Behan, Courtney M. Krest, 2013, Science.

Effect of flavoring chemicals on free radical formation in electronic cigarette aerosols

R. Elias, J. Muscat, A. Silakov, 2017, Free radical biology & medicine.

Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2.

C. Krebs, J. Bollinger, Michael T. Green, 2015, Journal of the American Chemical Society.

Unusual Synthetic Pathway for an {Fe(NO)2}(9) Dinitrosyl Iron Complex (DNIC) and Insight into DNIC Electronic Structure via Nuclear Resonance Vibrational Spectroscopy.

C. Krebs, N. Lehnert, E. Alp, 2016, Inorganic chemistry.

Impact of Atomizer Age and Flavor on in vitro Toxicity of Aerosols from a Third-Generation Electronic Cigarette against Human Oral Cells.

J. Lambert, R. Elias, A. Silakov, 2020, Chemical research in toxicology.

Structural, Electronic, and Magnetic Characterization of a Dinuclear Zinc Complex Containing TCNQ(-) and a μ-[TCNQ-TCNQ](2-) Ligand.

A. Silakov, H. Yennawar, Juyeong Kim, 2015, Inorganic chemistry.

Evidence for Porphyrin-Mediated Electron Transfer in the Radical SAM Enzyme HutW

W. Lanzilotta, Marley Brimberry, Pa Corrigan, 2023, Biochemistry.

Chain Length and Solvent Control over the Electronic Properties of Alkanethiolate-Protected Gold Nanoparticles at the Molecule-to-Metal Transition.

L. Jensen, A. Silakov, Benjamin J. Lear, 2016, Journal of the American Chemical Society.

Direct Measurement of the Radical Translocation Distance in the Class I Ribonucleotide Reductase from Chlamydia trachomatis.

C. Krebs, J. Bollinger, Ryan J. Martinie, 2015, The journal of physical chemistry. B.

Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer.

K. Yokoyama, C. Krebs, J. Bollinger, 2013, Journal of the American Chemical Society.

Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor.

C. Pollock, C. Krebs, J. Bollinger, 2018, Biochemistry.

Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine

A. Silakov, Bo Wang, A. Blaszczyk, 2017, The Journal of Biological Chemistry.

Spectroscopic and Electrochemical Characterization of the Iron-Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase.

S. Elliott, C. Krebs, Bo Zhang, 2016, Journal of the American Chemical Society.

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance.

C. Krebs, J. Bollinger, Bo Zhang, 2018, Journal of the American Chemical Society.

Spectroelectrochemical characterization of the active site of the [FeFe] hydrogenase HydA1 from Chlamydomonas reinhardtii.

W. Lubitz, T. Happe, A. Silakov, 2009, Biochemistry.

Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.

G. Evans, S. Almo, G. Gerfen, 2020, Biochemistry.

Characterization of Radical S-adenosylmethionine Enzymes and Intermediates in their Reactions by Continuous Wave and Pulse Electron Paramagnetic Resonance Spectroscopies

A. Silakov, S. Booker, N. Lanz, 2017 .

A model of the [FeFe] hydrogenase active site with a biologically relevant azadithiolate bridge: a spectroscopic and theoretical investigation.

W. Lubitz, S. Ott, E. Reijerse, 2011, Angewandte Chemie.

The [FeFe]‐hydrogenase maturase HydF from Clostridium acetobutylicum contains a CO and CN− ligated iron cofactor

W. Lubitz, T. Happe, A. Silakov, 2010, FEBS letters.

Characterization of a selenocysteine-ligated P450 compound I reveals direct link between electron donation and reactivity.

Michael T. Green, A. Silakov, Timothy H. Yosca, 2017, Nature chemistry.

Stable Open-Shell Phosphorane Based on a Redox-Active Amidodiphenoxide Scaffold.

A. Silakov, H. Yennawar, Allen J. Pistner, 2017, Inorganic chemistry.

EPR/ENDOR, Mössbauer, and quantum-chemical investigations of diiron complexes mimicking the active oxidized state of [FeFe]hydrogenase.

W. Lubitz, T. Rauchfuss, A. Silakov, 2012, Inorganic chemistry.

Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase.

Benjamin D. Allen, C. Pollock, C. Krebs, 2017, Journal of the American Chemical Society.

Evidence for a Di-μ-oxo Diamond Core in the Mn(IV)/Fe(IV) Activation Intermediate of Ribonucleotide Reductase from Chlamydia trachomatis.

C. Pollock, C. Krebs, J. Bollinger, 2017, Journal of the American Chemical Society.

Significantly shorter Fe-S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidase

Michael T. Green, Courtney M. Krest, J. Rittle, 2015, Nature chemistry.

Advanced electron paramagnetic resonance and density functional theory study of a {2Fe3S} cluster mimicking the active site of [FeFe] hydrogenase.

W. Lubitz, A. Silakov, J. Shaw, 2010, Journal of the American Chemical Society.

Use of Noncanonical Tyrosine Analogues to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1).

C. Krebs, J. Bollinger, Chi-Yun Lin, 2022, ACS catalysis.

Use of Non-canonical Tyrosine Analogs to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

C. Krebs, A. Silakov, Chi-Yun Lin, 2022 .

Probing ligand-induced modulation of metallic states in small gold nanoparticles using conduction electron spin resonance.

L. Jensen, Anthony Cirri, Alexey Silakov, 2016, Physical chemistry chemical physics : PCCP.

The First Step in Catalysis of the Radical S-Adenosylmethionine Methylthiotransferase MiaB Yields an Intermediate with a [3Fe-4S]0-like Auxiliary Cluster.

C. Krebs, A. Silakov, B. Zhang, 2020, Journal of the American Chemical Society.

Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA.

S. Elliott, Weitao Yang, K. Yokoyama, 2021, Journal of the American Chemical Society.

Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes.

C. Pollock, C. Krebs, J. Bollinger, 2017, Inorganic chemistry.

Investigation of the Unusual Ability of the [FeFe] Hydrogenase from Clostridium beijerinckii to Access an O2‐Protected State

Alexey Silakov, Patrick S Corrigan, 2021, The FASEB Journal.

Ligand Control over the Electronic Properties within the Metallic Core of Gold Nanoparticles.

A. Silakov, Benjamin J. Lear, Anthony Cirri, 2015, Angewandte Chemie.

Evidence of Atypical Structural Flexibility of the Active Site Surrounding of an [FeFe] Hydrogenase from Clostridium beijerinkii.

Alexey Silakov, Patrick S Corrigan, Sean H. Majer, 2023, Journal of the American Chemical Society.

A pulsed EPR study of clustering of Yb3+ ions incorporated in GeO2 glass

S. Sen, A. Silakov, R. Rakhmatullin, 2004 .

Analysis of RNA methylation by phylogenetically diverse Cfr radical SAM enzymes reveals an iron-binding accessory domain in a clostridial enzyme.

C. Krebs, Ryan J. Martinie, S. Booker, 2019, Biochemistry.

Iron(IV)hydroxide pKa and the Role of Thiolate Ligation in C–H Bond Activation by Cytochrome P450

Michael T. Green, Rachel K. Behan, Courtney M. Krest, 2013, Science.

Characterization of a selenocysteine-ligated P450 compound I reveals direct link between electron donation and reactivity.

Michael T. Green, Timothy H. Yosca, Alexey Silakov, 2017, Nature chemistry.

Isolation and first EPR characterization of the [FeFe]-hydrogenases from green algae.

W. Lubitz, E. Reijerse, T. Happe, 2008, Biochimica et biophysica acta.

Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase.

Ryan J. Martinie, Debangsu Sil, C. Pollock, 2024, Journal of the American Chemical Society.

Synergistic Binding of the Halide and Cationic Prime Substrate of l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States.

C. Krebs, J. Bollinger, Debangsu Sil, 2023, Biochemistry.

Synergistic Binding of the Halide and Cationic Prime Substrate of the l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States

C. Krebs, Debangsu Sil, Chi-Yun Lin, 2023, bioRxiv.