Jesus A. Alonso

Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner

L. Hellman, N. Singh, Jesus A Alonso, 2021, Proceedings of the National Academy of Sciences.

A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry

L. Hellman, J. Devlin, Grant L. J. Keller, 2022, Nature Communications.

Tumor rejection properties of gp100209-specific T cells correlate with T cell receptor binding affinity towards the wild type rather than anchor-modified antigen.

B. Baker, Angela R. Smith, Jesus A. Alonso, 2021, Molecular immunology.

An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.

L. Hellman, N. Singh, B. Baker, 2020, Biochemistry.

Structural dissimilarity from self drives neoepitope escape from immune tolerance

G. Coukos, J. Devlin, Cory M. Ayres, 2020, Nature Chemical Biology.

T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability

K. Garcia, L. Hellman, Kendra C. Foley, 2018, Nature Chemical Biology.

Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality

K. Roskin, B. Baker, David A Hildeman, 2023, bioRxiv.

Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.

Y. Zhang, L. Hellman, Kendra C. Foley, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality

J. T. Caldwell, K. Roskin, B. Baker, 2023, The Journal of clinical investigation.