Andrew L. Lee

发表

Mapping allosteric communications within individual proteins

Nikolay V. Dokholyan, Jian Wang, Abha Jain, 2020, Nature Communications.

Redistribution and loss of side chain entropy upon formation of a calmodulin–peptide complex

Andrew L. Lee, Sandra A. Kinnear, A. Wand, 2000, Nature Structural Biology.

Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase.

Andrew L. Lee, Laura E. Herring, Jeffrey P Bonin, 2019, Biophysical journal.

Chemical shift imprint of intersubunit communication in a symmetric homodimer

Andrew L. Lee, P. Sapienza, Bradley T. Falk, 2016, Proceedings of the National Academy of Sciences.

Segmental motions, not a two-state concerted switch, underlie allostery in CheY.

Andrew L. Lee, L. McDonald, J. Boyer, 2012, Structure.

Backbone and side chain dynamics of mutant calmodulin-peptide complexes.

Andrew L. Lee, A Joshua Wand, A. Wand, 2005, Biochemistry.

Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.

Jun Zhang, Andrew L. Lee, George N Phillips, 2010, Biochemistry.

Hidden dynamic allostery in a PDZ domain

Andrew L. Lee, Jun Zhang, Ernesto J Fuentes, 2009, Proceedings of the National Academy of Sciences.

Evaluation of energetic and dynamic coupling networks in a PDZ domain protein.

Andrew L. Lee, Ernesto J Fuentes, E. J. Fuentes, 2006, Journal of molecular biology.

Dynamic coupling and allosteric behavior in a nonallosteric protein.

Andrew L. Lee, M. Edgell, Steven A. Gilmore, 2006, Biochemistry.

Ligand-dependent dynamics and intramolecular signaling in a PDZ domain.

Andrew L. Lee, Channing J Der, Ernesto J Fuentes, 2004, Journal of molecular biology.

Monitoring aromatic picosecond to nanosecond dynamics in proteins via 13C relaxation: expanding perturbation mapping of the rigidifying core mutation, V54A, in eglin c.

Andrew L. Lee, J. Boyer, Andrew L Lee, 2008, Biochemistry.

Frameworks for understanding long-range intra-protein communication.

Andrew L. Lee, M. J. Whitley, Andrew L Lee, 2009, Current protein & peptide science.

A larger pool of ozone-forming carbon compounds in urban atmospheres

Andrew L. Lee, P. Marriott, A. Lewis, 2000, Nature.

Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.

Andrew L. Lee, M. Clarkson, 2004, Biochemistry.

Assessing potential bias in the determination of rotational correlation times of proteins by NMR relaxation

Andrew L. Lee, A. Joshua Wand, A. Wand, 1999, Journal of biomolecular NMR.

Erratum (Retracted article): Protein dynamics in living cells (Biochemistry (2005) 44, 26, (9275-9279))

Andrew L. Lee, Gary J. Pielak, G. Pielak, 2007 .

Microscopic origins of entropy, heat capacity and the glass transition in proteins

Andrew L. Lee, A. Joshua Wand, A. Wand, 2001, Nature.

Direct detection of structurally resolved dynamics in a multiconformation receptor-ligand complex.

Andrew L. Lee, Ashutosh Tripathy, Edward J. Collins, 2011, Journal of the American Chemical Society.

A Model of Peak Amplitude Enhancement in Orthogonal Two-Dimensional Gas Chromatography

Andrew L. Lee, A. Lewis, K. Bartle, 2001 .

A comparison of modulating interface technologies in comprehensive two‐dimensional gas chromatography (GC×GC)

Andrew L. Lee, P. Marriott, A. Lewis, 2000 .

Protein Mass Effects on Formate Dehydrogenase.

Andrew L. Lee, P. Sapienza, A. Kohen, 2017, Journal of the American Chemical Society.

An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures.

Andrew L. Lee, C. Carter, P. Sapienza, 2016, ACS chemical biology.

Nuclear magnetic resonance study of the role of M42 in the solution dynamics of Escherichia coli dihydrofolate reductase.

Andrew L. Lee, Randall V. Mauldin, 2010, Biochemistry.

Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor.

Andrew L. Lee, M. Clarkson, A. Sancar, 2005, Biochemistry.

Monitoring Aromatic ps-ns Dynamics in Proteins via 13 C Relaxation: Expanding Perturbation Mapping of the Rigidifying Core Mutation, V54A, in eglin c †

Andrew L. Lee, J. Boyer, 2011 .

Crystallographic and NMR evaluation of the impact of peptide binding to the second PDZ domain of PTP1E

Andrew L. Lee, G. Phillips, H. Ke, 2011 .

Hydrophobic core mutations in CI2 globally perturb fast side-chain dynamics similarly without regard to position.

Andrew L. Lee, Jun Zhang, M. J. Whitley, 2008, Biochemistry.

Redox-Dependent Magnetic Alignment of Clostridium pasteurianum Rubredoxin: Measurement of Magnetic Susceptibility Anisotropy and Prediction of Pseudocontact Shift Contributions

Andrew L. Lee, W. M. Westler, J. Markley, 1999 .

Evidence for dynamics in proteins as a mechanism for ligand dissociation

Andrew L. Lee, Randall V. Mauldin, S. Singleton, 2011, Nature chemical biology.

Monitoring side-chain dynamics of proteins using (2)H relaxation.

Andrew L. Lee, C. M. Petit, 2014, Methods in molecular biology.

Colocalization of fast and slow timescale dynamics in the allosteric signaling protein CheY.

Andrew L. Lee, L. McDonald, J. Boyer, 2013, Journal of molecular biology.

Multi-timescale dynamics study of FKBP12 along the rapamycin-mTOR binding coordinate.

Andrew L. Lee, P. Sapienza, Randall V. Mauldin, 2011, Journal of molecular biology.

NMR study of the role of M42 in the solution dynamics of E. COLI dihydrofolate reductase†

Andrew L. Lee, Randall V. Mauldin, 2010 .

Phosphorylation of a PDZ Domain Extension Modulates Binding Affinity and Interdomain Interactions in Postsynaptic Density-95 (PSD-95) Protein, a Membrane-associated Guanylate Kinase (MAGUK)*

Andrew L. Lee, D. King, Jun Zhang, 2011, The Journal of Biological Chemistry.

Protein dynamics in living cells.

Andrew L. Lee, G. Pielak, G. B. Young, 2005, Biochemistry.

Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.

Andrew L. Lee, R. Stroud, J. Finer-Moore, 2013, Journal of the American Chemical Society.

Structure and Dynamics of the G121V Dihydrofolate Reductase Mutant: Lessons from a Transition-State Inhibitor Complex

Andrew L. Lee, P. Sapienza, Randall V. Mauldin, 2012, PloS one.

Using NMR to study fast dynamics in proteins: methods and applications.

Andrew L. Lee, P. Sapienza, Paul J Sapienza, 2010, Current opinion in pharmacology.

Conservation of side-chain dynamics within a protein family.

Andrew L. Lee, Ernesto J Fuentes, Andrew L Lee, 2009, Journal of the American Chemical Society.

Dynamic dysfunction in dihydrofolate reductase results from antifolate drug binding: modulation of dynamics within a structural state.

Andrew L. Lee, Randall V. Mauldin, M. Carroll, 2009, Structure.

Relating side-chain mobility in proteins to rotameric transitions: Insights from molecular dynamics simulations and NMR

Andrew L. Lee, J. Hermans, Hao Hu, 2005, Journal of biomolecular NMR.

Nuclear Magnetic Resonance (NMR) Spectroscopy for Monitoring Molecular Dynamics in Solution

Andrew L. Lee, A. Wand, 2001 .

The Effect of Protein Mass Modulation on Human Dihydrofolate Reductase.

Andrew L. Lee, P. Sapienza, A. Kohen, 2016, Biochemistry.

Isotopic Labeling of Formate Dehydrogenase Perturbs the Protein Dynamics.

Andrew L. Lee, P. Sapienza, A. Kohen, 2019, The journal of physical chemistry. B.

Inter-Active Site Communication Mediated by the Dimer Interface Beta-Sheet in the Half-the-Sites Enzyme, Thymidylate Synthase.

Andrew L. Lee, N. Dokholyan, P. Sapienza, 2019, Biochemistry.

Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase

Andrew L. Lee, P. Sapienza, Paul J. Sapienza, 2018, Front. Mol. Biosci..

Widespread Perturbation of Function, Structure, and Dynamics by a Conservative Single-Atom Substitution in Thymidylate Synthase.

Andrew L. Lee, P. Sapienza, 2016, Biochemistry.

Contrasting roles of dynamics in protein allostery: NMR and structural studies of CheY and the third PDZ domain from PSD-95

Andrew L. Lee, 2015, Biophysical Reviews.

Exploring the role of structure and dynamics in the function of chymotrypsin inhibitor 2

Andrew L. Lee, M. J. Whitley, 2011, Proteins.

Detection of native-state nonadditivity in double mutant cycles via hydrogen exchange.

Andrew L. Lee, M. Edgell, J. Boyer, 2010, Journal of the American Chemical Society.

Dynamic allostery in substrate binding by human thymidylate synthase

Andrew L. Lee, P. Sapienza, Jeffrey P. Bonin, 2022, bioRxiv.

Backbone and ILV methyl resonance assignments of E. coli thymidylate synthase bound to cofactor and a nucleotide analogue

Andrew L. Lee, P. Sapienza, 2014, Biomolecular NMR assignments.

Backbone and ILV methyl resonance assignments of E. coli thymidylate synthase bound to cofactor and a nucleotide analogue

Andrew L. Lee, P. Sapienza, 2013, Biomolecular NMR Assignments.

Visualizing an Allosteric Intermediate Using CuAAC Stabilization of an NMR Mixed Labeled Dimer.

Andrew L. Lee, P. Sapienza, D. Goldfarb, 2021, ACS chemical biology.

Backbone and ILVM methyl resonance assignments of human thymidylate synthase in apo and substrate bound forms

Andrew L. Lee, Jeffrey P. Bonin, 2021, Biomolecular NMR assignments.

Bacterial Thymidylate Synthase Binds Two Molecules of Substrate and Cofactor without Cooperativity.

Andrew L. Lee, P. Sapienza, Bradley T. Falk, 2015, Journal of the American Chemical Society.

Improved labeling strategy for 13C relaxation measurements of methyl groups in proteins

Andrew L. Lee, A. Wand, A. L. Lee, 1997, Journal of biomolecular NMR.

Direct Demonstration of Structural Similarity between Native and Denatured Eglin C †

Andrew L. Lee, D. Shortle, M. Edgell, 2004 .

CuAAC stabilization of an NMR mixed labeled dimer

Andrew L. Lee, P. Sapienza, J. Aubé, 2021, bioRxiv.

Supertertiary structure of the MAGUK core from PSD-95.

Andrew L. Lee, Steven M. Lewis, B. Kuhlman, 2013, Structure.

Allosteric inactivation of an engineered optogenetic GTPase

Andrew L. Lee, N. Dokholyan, Abha Jain, 2022, bioRxiv.

Solution Structure of Polymerase μ’s BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining

Andrew L. Lee, D. Ramsden, Jody M. Havener, 2007 .

Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.

Andrew L. Lee, R. Stroud, J. Finer-Moore, 2013, Journal of the American Chemical Society.

Virus Structure & Assembly

Andrew L. Lee, W. Roos, Paul, 2008, Biophysical Journal.

Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.

Andrew L. Lee, G. Phillips, H. Ke, 2010, Biochemistry.