George D. Loizou

发表

Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using in silico, in vitro and human biomonitoring data

K. McNally, C. Sams, A. Hogg, 2023, Frontiers in Pharmacology.

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Pim E G Leonards, Philippe Rocca-Serra, Richard D Beger, 2019, Nature Communications.

Development, testing, parameterisation, and calibration of a human PBK model for the plasticiser, di (2-ethylhexyl) adipate (DEHA) using in silico, in vitro and human biomonitoring data

K. McNally, C. Sams, George D. Loizou, 2023, Frontiers in Pharmacology.

Refinement and calibration of a human PBPK model for the plasticiser, Di-(2-propylheptyl) phthalate (DPHP) using in silico, in vitro and human biomonitoring data

K. McNally, George D. Loizou, 2023, Frontiers in Pharmacology.

A quantitative structure–activity relationship analysis on a series of alkyl benzenes metabolized by human cytochrome P450 2E1

D. Lewis, G. Loizou, David F V Lewis, 2003, Journal of biochemical and molecular toxicology.

The utility of PBPK in the safety assessment of chloroform and carbon tetrachloride.

A. J. MacDonald, G. Loizou, P. Lilly, 2000, Regulatory toxicology and pharmacology : RTP.

Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene

M. Andersen, H. Clewell, P. Gentry, 2023, Frontiers in pharmacology.

Evidence for non-linear metabolism at low benzene exposures? A reanalysis of data.

C. Sams, George D. Loizou, Kevin McNally, 2017, Chemico-biological interactions.

INTEGRA: From global scale contamination to tissue dose,

E. Handakas, D. Sarigiannis, A. Gotti, 2014 .