J. F. Burrows

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Not Unles You Ask Nicely: The Interpretative Nexus Between Analysis and Information

J. F. Burrows, J. Burrows, 1992 .

Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3

J. F. Burrows, P. Johnston, S. Russell, 2001, Oncogene.

Evaluation of the In Vitro Cytotoxicity and Modulation of the Inflammatory Response by the Bioresorbable Polymers Poly(D,L-lactide-co-glycolide) and Poly(L-lactide-co-glycolide).

J. F. Burrows, F. Buchanan, L. Carson, 2021, Acta biomaterialia.

Evaluation of the in Vitro Cytotoxicity and Modulation of the Inflammatory Response by the Bioresorbable Polymers Poly(D,L-Lactide-Co-Glycolide) and Poly(L-Lactide-Co-Glycolide)

J. F. Burrows, J. Burrows, F. Buchanan, 2021, Acta biomaterialia.

Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy

J. F. Burrows, J. Burrows, Xinping Xi, 2020, Biology.

Modiﬁcation and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic E ﬃ cacy

J. F. Burrows, J. Burrows, Xinping Xi, 2020 .

Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation

J. F. Burrows, J. Johnston, D. McAuley, 2015, Science Translational Medicine.

Brevinin-2GHk from Sylvirana guentheri and the Design of Truncated Analogs Exhibiting the Enhancement of Antimicrobial Activity

J. F. Burrows, J. Burrows, Xinping Xi, 2020, Antibiotics.

Design of N-Terminal Derivatives from a Novel Dermaseptin Exhibiting Broad-Spectrum Antimicrobial Activity against Isolates from Cystic Fibrosis Patients

J. F. Burrows, M. Wei, J. Burrows, 2019, Biomolecules.

Identification and target-modifications of temporin-PE: A novel antimicrobial peptide in the defensive skin secretions of the edible frog, Pelophylax kl. esculentus.

J. F. Burrows, Qinan Wu, Xinping Xi, 2018, Biochemical and biophysical research communications.

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

J. F. Burrows, J. Johnston, J. Burrows, 2005, Genomics.

Cathepsin V suppresses GATA3 protein expression in luminal A breast cancer

J. F. Burrows, C. Scott, R. Burden, 2020, Breast cancer research : BCR.

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility

J. F. Burrows, J. Johnston, K. Dib, 2011, Nature communications.

USP17 Regulates Ras Activation and Cell Proliferation by Blocking RCE1 Activity*

J. F. Burrows, J. Johnston, K. Dib, 2009, Journal of Biological Chemistry.

USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells

J. F. Burrows, S. Van Schaeybroeck, J. Burrows, 2018, Cell Communication and Signaling.

De-ubiquitinating enzymes: intracellular signalling and disease.

J. F. Burrows, J. Johnston, J. Burrows, 2006, Biochemical Society transactions.

DUB-3, a Cytokine-inducible Deubiquitinating Enzyme That Blocks Proliferation*

J. F. Burrows, J. Johnston, K. Baek, 2004, Journal of Biological Chemistry.

USP17 is required for peripheral trafficking of lysosomes

J. F. Burrows, P. Mullan, J. Simpson, 2022, EMBO reports.

The DUB / USP 17 deubiquitinating enzymes : A gene family within a tandemly repeated sequence

J. F. Burrows, J. Johnston, J. Burrows, 2010 .

The DUB/USP17 deubiquitinating enzymes: A gene family within a tandemly repeated sequence, is also embedded within the copy number variable Beta-defensin cluster

J. F. Burrows, J. Johnston, J. Burrows, 2010, BMC Genomics.

Large Molecule Therapeutics A Highly Potent and Speci fi c MET Therapeutic Protein Antagonist with Both Ligand-Dependent and Ligand-Independent Activity

J. F. Burrows, L. Audoly, H. Martin, 2013 .

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

J. F. Burrows, J. Johnston, U. Govender, 2010, Cancer research.

Tumor and Stem Cell Biology Cancer Research The Deubiquitinating Enzyme USP 17 Is Highly Expressed in Tumor Biopsies , Is Cell Cycle Regulated , and Is Required for G 1S Progression

J. F. Burrows, J. Johnston, U. Govender, 2010 .

Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages

J. F. Burrows, E. Lavelle, J. Burrows, 2015, Particle and Fibre Toxicology.

Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production1

J. F. Burrows, J. Johnston, W. Coulter, 2009, The Journal of Immunology.

Cathepsin S from both tumor and tumor‐associated cells promote cancer growth and neovascularization

J. F. Burrows, J. Johnston, A. Kissenpfennig, 2013, International journal of cancer.

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation

J. F. Burrows, I. Mills, Mandy Rettel, 2021, Cell Death & Disease.

Respiratory Syncytial Virus NS1 Protein Degrades STAT2 by Using the Elongin-Cullin E3 Ligase

J. F. Burrows, J. Johnston, M. Gadina, 2007, Journal of Virology.

Deubiquitylating enzymes in receptor endocytosis and trafficking.

J. F. Burrows, S. Van Schaeybroeck, C. Scott, 2016, The Biochemical journal.

The Deubiquitinating Enzyme USP17 Blocks N-Ras Membrane Trafficking and Activation but Leaves K-Ras Unaffected

J. F. Burrows, J. Johnston, U. Govender, 2010, The Journal of Biological Chemistry.

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.

J. F. Burrows, J. Johnston, Joanne Elliott, 2007, Blood.

Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor

J. F. Burrows, J. Duan, J. Burrows, 2019, Biomolecules.

Regulation of cellular responses by deubiquitinating enzymes: an update.

J. F. Burrows, J. Johnston, 2012, Frontiers in bioscience.

Altered expression of the septin gene, SEPT9, in ovarian neoplasia

J. F. Burrows, P. Johnston, A. Godwin, 2003, The Journal of pathology.

Enhanced Antitumor Activity of the Photosensitizer meso-Tetra(N-methyl-4-pyridyl) Porphine Tetra Tosylate through Encapsulation in Antibody-Targeted Chitosan/Alginate Nanoparticles

J. F. Burrows, D. Longley, D. Schmid, 2013, Biomacromolecules.

Ubiquitination: Added complexity in Ras and Rho family GTPase function.

J. F. Burrows, J. Johnston, Michelle de la Vega, 2011, Small GTPases.

Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme

J. F. Burrows, H. McCarthy, N. Dunne, 2020, Journal of Nanobiotechnology.

Ubiquitination

J. F. Burrows, J. Johnston, M. de la Vega, 2011, Co and Post-Translational Modifications of Therapeutic Antibodies and Proteins.

Targeted Modification and Structure-Activity Study of GL-29, an Analogue of the Antimicrobial Peptide Palustrin-2ISb

J. F. Burrows, Jiachen Liu, J. Burrows, 2022, Antibiotics.

Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer

J. F. Burrows, D. Longley, S. Caddick, 2020, British Journal of Cancer.

A Highly Potent and Specific MET Therapeutic Protein Antagonist with Both Ligand-Dependent and Ligand-Independent Activity

J. F. Burrows, L. Audoly, M. Hülsmeyer, 2013, Molecular Cancer Therapeutics.

Refined construction of antibody-targeted nanoparticles leads to superior antigen binding and enhanced delivery of an entrapped payload to pancreatic cancer cells.

J. F. Burrows, Daniel A. Richards, D. Longley, 2020, Nanoscale.

A novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells

J. F. Burrows, J. Burrows, Xinping Xi, 2018, Bioscience reports.

Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii

J. F. Burrows, H. Kwok, Xinping Xi, 2018, Toxins.

proteasomal-mediated turnover CD33 responses are blocked by SOCS3 through accelerated

J. F. Burrows, J. Johnston, Joanne Elliott, 2013 .

Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.

J. F. Burrows, J. Weissenbach, P. Johnston, 2000, Cancer research.

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

J. F. Burrows, J. Johnston, J. Rappoport, 2014, Oncotarget.

SOCS3 Targets Siglec 7 for Proteasomal Degradation and Blocks Siglec 7-mediated Responses*

J. F. Burrows, J. Johnston, C. Jefferies, 2006, Journal of Biological Chemistry.

Identification of novel Amurin-2 variants from the skin secretion of Rana amurensis, and the design of cationicity-enhanced analogues.

J. F. Burrows, J. Burrows, Xinping Xi, 2018, Biochemical and biophysical research communications.

A Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities

J. F. Burrows, J. Burrows, Xinping Xi, 2019, Biomolecules.

From netrin‐1‐targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors

J. F. Burrows, P. Mullan, J. Simpson, 2022, EMBO reports.

A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17.

J. F. Burrows, J. Johnston, N. Rawlings, 2014, The Biochemical journal.

USP 17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

J. F. Burrows, J. Rappoport, Sarah J. Fletcher, 2014 .

USP17-like Peptidase/DUB3 Peptidase

J. F. Burrows, J. Johnston, C. Scott, 2013 .

A frog‐derived antimicrobial peptide as a potential anti‐biofilm agent in combating Staphylococcus aureus skin infection

J. F. Burrows, Lei Wang, J. Duan, 2023, Journal of Cellular and Molecular Medicine.

Structure–activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities

J. F. Burrows, Lei Wang, Xinping Xi, 2019, Drug design, development and therapy.

structure–activity relationship of an antimicrobial peptide, Phylloseptin-Pha: balance of hydrophobicity and charge determines the selectivity of bioactivities

J. F. Burrows, Lei Wang, Xinping Xi, 2019 .

Advances in Brief Isolation and Mapping of a Human Septin Gene to a Region on Chromosome 17 q , Commonly Deleted in Sporadic Epithelial Ovarian Tumors 1

J. F. Burrows, J. Weissenbach, P. Johnston, 2000 .

Isolation and Mapping of a Human SeptinGene to a Region on Chromosome 17q, Commonly Deleted in Sporadic Epithelial Ovarian Tumors

J. F. Burrows, J. Weissenbach, E. Petty, 2000 .

Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen

J. F. Burrows, H. McCarthy, L. McClements, 2014, Oncogene.

Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production

J. F. Burrows, J. Johnston, W. Coulter, 2010, The Journal of Immunology.