Mariateresa Giustiniano

发表

A. Massarotti, G. Tron, M. Giustiniano, 2021, Chemical reviews.

Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.

E. Novellino, B. Pagano, L. Marinelli, 2012, Journal of medicinal chemistry.

Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.

Ettore Novellino, Luciana Marinelli, Sandro Cosconati, 2017, Journal of medicinal chemistry.

Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.

E. Novellino, S. Taliani, C. Martini, 2015, Journal of medicinal chemistry.

Pharmacological folding chaperones act as allosteric ligands of Frizzled4.

E. Novellino, R. Silvestri, G. La Regina, 2015, Nature chemical biology.

Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: Synthesis and biological evaluation.

E. Novellino, A. Caldarelli, P. Canonico, 2011, Bioorganic & medicinal chemistry letters.

Back to the Medicinal Chemistry Future.

C. Gruber, P. Trippier, Christian W. Gruber, 2021, Journal of medicinal chemistry.

Visible-Light Photocatalytic Functionalization of Isocyanides for the Synthesis of Secondary Amides and Ketene Aminals

E. Novellino, V. Summa, Jussara Amato, 2020, The Journal of organic chemistry.

Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island

E. Novellino, A. Basso, G. Tron, 2018, Synthesis.

Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement.

E. Novellino, F. Meneghetti, A. Massarotti, 2015, The Journal of organic chemistry.

Bio-Inspired Dual Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives.

E. Novellino, B. Pagano, Jussara Amato, 2020, Journal of medicinal chemistry.

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds.

E. Novellino, G. Tron, M. Giustiniano, 2020, Chemical Society reviews.

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

E. Novellino, F. Meneghetti, G. Tron, 2019, Molecules.

Exploiting the Electrophilic and Nucleophilic Dual Role of Nitrile Imines: One-Pot, Three-Component Synthesis of Furo[2,3-d]pyridazin-4(5H)-ones.

E. Novellino, Jussara Amato, G. Tron, 2015, Organic letters.

α-Amino Acids as Synthons in the Ugi-5-Centers-4-Components Reaction: Chemistry and Applications

Ettore Novellino, Gian Cesare Tron, Sveva Pelliccia, 2019, Symmetry.

Visible-Light Photoredox Catalysis in Water

G. Tron, M. Giustiniano, Francesca Brunelli, 2022, The Journal of organic chemistry.

The Dark Side of Isocyanides: Visible-Light Photocatalytic Activity in the Oxidative Functionalization of C(sp3)–H Bonds

Jussara Amato, G. Tron, M. Giustiniano, 2021, The Journal of organic chemistry.

Visible-Light Photocatalytic Ugi/Aza-Wittig Cascade towards 2-Aminomethyl-1,3,4-oxadiazole Derivatives

G. Tron, M. Giustiniano, R. Cannalire, 2021, Synthesis.

The 115 Years Old Multicomponent Bargellini Reaction: Perspectives and New Applications

G. Tron, T. Pirali, M. Giustiniano, 2021, Molecules.

To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis.

E. Novellino, A. Basso, A. Massarotti, 2017, Chemical Society reviews.

Enriching the Arsenal of Pharmacological Tools against MICAL2

F. Da Settimo, S. Taliani, D. Brancaccio, 2021, Molecules.

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells.

E. Novellino, F. Da Settimo, S. Taliani, 2017, ACS chemical neuroscience.

Nitrile N-Oxides and Nitrile Imines as New Fuels for the Discovery of Novel Isocyanide-Based Multicomponent Reactions

E. Novellino, G. Tron, Mariateresa Giustiniano, 2016, Synthesis.

Amphoteric 2-(sulfonylamino)benzaldehydes, secondary amines and isocyanides in the multicomponent synthesis of elusive N-alkyl-2,3-diaminoindoles

E. Novellino, F. Meneghetti, G. Tron, 2017 .

Multicomponent Reaction Between (Z)-Chloroximes, Isocyanides And NH-Heterocyclic Rings

Francesca Brunelli, Camilla Russo, U. Galli, 2021, Tetrahedron Letters.

Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans.

E. Novellino, A. Massarotti, G. Tron, 2019, The Journal of organic chemistry.

A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide

E. Novellino, Michele Pavone, B. Pagano, 2017 .

A Successful Replacement of Phenols with Isocyanides in the Bargellini Reaction: Synthesis of 3-Carboxamido-Isobutyric Acids.

E. Novellino, G. Tron, M. Giustiniano, 2016, The Journal of organic chemistry.

Reaction between (Z)-arylchlorooximes and α-isocyanoacetamides: a procedure for the synthesis of aryl-α-ketoamide amides.

E. Novellino, S. Di Maro, G. Tron, 2014, The Journal of organic chemistry.

Non-hydrolytic chemoselective cleavage of Ugi tertiary amides: A mild access to N-substituted α-amino acid amides

E. Novellino, G. Tron, M. Giustiniano, 2018 .

Aryl azides as forgotten electrophiles in the Van Leusen reaction: a multicomponent transformation affording 4-tosyl-1-arylimidazoles.

E. Novellino, F. Meneghetti, G. Tron, 2019, The Journal of organic chemistry.

Photomicellar Catalyzed Synthesis of Amides from Isocyanides: Optimization, Scope, and NMR Studies of Photocatalyst/Surfactant Interactions

A. Carotenuto, G. Graziani, G. Tron, 2021, ACS organic & inorganic Au.

Synthesis of aminocarbonyl N-acylhydrazones by a three-component reaction of isocyanides, hydrazonoyl chlorides, and carboxylic acids.

E. Novellino, F. Meneghetti, G. Tron, 2014, Organic letters.

Isocyanide-based Multicomponent Reactions Promoted by Visible Light Photoredox Catalysis.

G. Tron, Francesca Brunelli, Camilla Russo, 2022, Chemistry.

A stereoselective approach to peptidomimetic BACE1 inhibitors.

E. Novellino, Simone Brogi, M. Brindisi, 2013, European journal of medicinal chemistry.

Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies.

E. Novellino, P. Huleatt, M. Brindisi, 2013, Bioorganic & medicinal chemistry letters.

Rational modifications on a benzylidene-acrylohydrazide antiviral scaffold, synthesis and evaluation of bioactivity against Chikungunya virus.

E. Novellino, A. Brancale, L. Delang, 2018, European journal of medicinal chemistry.

Amino Acid Derivatives as New Zinc Binding Groups for the Design of Selective Matrix Metalloproteinase Inhibitors

E. Novellino, A. Di Pizio, A. Bertamino, 2013, Journal of amino acids.

In-water synthesis of isocyanides under micellar conditions

G. Tron, S. Aprile, Francesca Brunelli, 2022, Green Chemistry.

Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step.

E. Novellino, F. Da Settimo, C. La Motta, 2012, European journal of medicinal chemistry.

Exploiting the Different Nucleophilicity of the Isocyano Group: A Strategy for the Isocyanide Functionalization.

G. Tron, Francesca Brunelli, Camilla Russo, 2024, The Journal of organic chemistry.