Salvatore Di Maro

发表

Novel α-MSH Peptide Analogues with Broad Spectrum Antimicrobial Activity

E. Novellino, P. Grieco, I. Gomez-Monterrey, 2013, PloS one.

Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides.

E. Novellino, P. Grieco, D. Brancaccio, 2019, Journal of medicinal chemistry.

Efficient solid-phase synthesis of FK228 analogues as potent antitumoral agents.

J. Hsieh, Jung-Mo Ahn, R. Pong, 2008, Journal of medicinal chemistry.

Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist.

E. Novellino, L. Portella, S. Scala, 2017, Journal of medicinal chemistry.

CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists.

V. Hruby, A. Mollica, M. Cai, 2022, Journal of medicinal chemistry.

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage

E. Gilson, E. Novellino, M. Mottolese, 2016, Nucleic acids research.

Irreversible inhibition of TRF2TRFH recruiting functions: a strategy to induce telomeric replication stress in cancer cells

A. Chambery, H. Pickett, L. Altucci, 2023, bioRxiv.

Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells.

E. Novellino, L. Altucci, A. Mai, 2012, Biochimie.

Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents.

E. Novellino, S. Taliani, C. Martini, 2015, Journal of medicinal chemistry.

Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells

F. Ciardiello, R. Bianco, T. Troiani, 2018, Oncotarget.

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.

E. Novellino, L. Portella, C. Ieranò, 2016, Journal of medicinal chemistry.

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity

E. Novellino, A. Mai, Xiaodong Cheng, 2014, PloS one.

Pharmacological folding chaperones act as allosteric ligands of Frizzled4.

E. Novellino, R. Silvestri, G. La Regina, 2015, Nature chemical biology.

Click‐Chemistry (CuAAC) Trimerization of an αvβ6 Integrin Targeting Ga‐68‐Peptide: Enhanced Contrast for in‐Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts

S. Di Maro, L. Marinelli, S. Kossatz, 2020, Chembiochem : a European journal of chemical biology.

Intestinal Anti-Inflammatory Effect of a Peptide Derived from Gastrointestinal Digestion of Buffalo (Bubalus bubalis) Mozzarella Cheese

R. Capasso, E. Novellino, G. Tenore, 2019, Nutrients.

Stable Peptides Instead of Stapled Peptides: Highly Potent αvβ6-Selective Integrin Ligands.

E. Novellino, M. Schwaiger, H. Kessler, 2016, Angewandte Chemie.

Neuropeptide S receptor ligands: a patent review (2005-2016)

S. Salvadori, S. Di Maro, C. Ruzza, 2017, Expert opinion on therapeutic patents.

Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.

E. Novellino, L. Altucci, A. Mai, 2012, Journal of medicinal chemistry.

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors

B. Pace, S. Sivanand, S. Di Maro, 2012, Anemia.

Disulfide bond replacement with 1,4- and 1,5-disubstituted [1,2,3]-triazole on C-X-C chemokine receptor type 4 (CXCR4) peptide ligands: small changes that make big differences.

E. Novellino, C. Ieranò, S. Scala, 2020, Chemistry.

Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer

H. Stunnenberg, L. Altucci, A. Mai, 2019, Cancers.

First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment

E. Novellino, P. Grieco, T. Grossmann, 2021, Journal of medicinal chemistry.

Urotensin-II Ligands: An Overview from Peptide to Nonpeptide Structures

Michele Caraglia, Paolo Grieco, P. Grieco, 2013, Journal of amino acids.

From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands.

E. Novellino, H. Kessler, D. Brancaccio, 2018, Angewandte Chemie.

Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence

L. Altucci, A. Nebbioso, G. Sbardella, 2020, Epigenetics.

Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.

M. Schwaiger, H. Kessler, S. Di Maro, 2019, Journal of medicinal chemistry.

A novel smaller β‐defensin‐derived peptide is active against multidrug‐resistant bacterial strains

F. Carbone, G. Matarese, F. Salvatore, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ultrasound-assisted Peptide Nucleic Acids synthesis (US-PNAS)

A. Chambery, F. Merlino, S. Cosconati, 2023, Ultrasonics sonochemistry.

Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication.

E. Novellino, P. Grieco, S. Di Maro, 2019, Organic letters.

Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.

E. Novellino, L. Portella, S. Scala, 2018, Journal of medicinal chemistry.

Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas.

E. Novellino, F. Da Settimo, S. Taliani, 2016, Journal of medicinal chemistry.

Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.

E. Novellino, F. Da Settimo, S. Taliani, 2018, Journal of medicinal chemistry.

3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.

E. Novellino, B. Cosimelli, G. Greco, 2012, Journal of medicinal chemistry.

Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer.

E. Novellino, S. Taliani, M. Trincavelli, 2017, Journal of medicinal chemistry.

Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.

E. Novellino, S. Di Maro, R. Di Santo, 2020, ACS Medicinal Chemistry Letters.

Reaction between (Z)-arylchlorooximes and α-isocyanoacetamides: a procedure for the synthesis of aryl-α-ketoamide amides.

E. Novellino, S. Di Maro, G. Tron, 2014, The Journal of organic chemistry.

Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.

E. Novellino, P. Grieco, V. Hruby, 2018, Journal of medicinal chemistry.

Water-soluble pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as human A₃ adenosine receptor antagonists.

K. Varani, S. Di Maro, L. Marinelli, 2012, Journal of medicinal chemistry.

Hepatocellular carcinoma (HCC) tumor microenvironment is more suppressive than colorectal cancer liver metastasis (CRLM) tumor microenvironment.

F. Izzo, L. Portella, C. Ieranò, 2023, Hepatology international.

New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.

E. Novellino, K. Varani, A. Zaid, 2011, Journal of medicinal chemistry.

Benzofuroxane derivatives as multi-effective agents for the treatment of cardiovascular diabetic complications. Synthesis, functional evaluation, and molecular modeling studies.

E. Novellino, F. Da Settimo, S. Taliani, 2012, Journal of medicinal chemistry.

Switchable Protecting Strategy for Solid Phase Synthesis of DNA and RNA Interacting Nucleopeptides.

A. Chambery, E. Novellino, S. Lama, 2016, The Journal of organic chemistry.

Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors

Christin Müller, J. Ziebuhr, S. Di Maro, 2022, European Journal of Medicinal Chemistry.

The organometallic ferrocene exhibits amplified anti-tumor activity by targeted delivery via highly selective ligands to αvβ3, αvβ6, or α5β1 integrins.

H. Kessler, S. Di Maro, U. Reuning, 2021, Biomaterials.

Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers.

A. Chambery, E. Novellino, C. Ieranò, 2018, Bioorganic & medicinal chemistry.

Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand

E. Novellino, H. Kessler, G. Quilici, 2021, Journal of medicinal chemistry.

Tailoring the Structure of Cell Penetrating DNA and RNA Binding Nucleopeptides

A. Chambery, L. Portella, C. Ieranò, 2022, International journal of molecular sciences.

Shading the TRF2 recruiting function: a new horizon in drug development.

E. Gilson, E. Novellino, B. Pagano, 2014, Journal of the American Chemical Society.

Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.

A. Chambery, H. Pickett, Anthony J. Cesare, 2023, Cell chemical biology.

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.

E. Novellino, L. Portella, C. Ieranò, 2016, Journal of medicinal chemistry.

Shading the TRF2 recruiting function: a new horizon in drug development.

E. Gilson, E. Novellino, C. Capasso, 2014, Journal of the American Chemical Society.

Development of an efficient solid-phase synthetic methodology to construct a combinatorial library of a potent HDAC inhibitor.

S. Di Maro, Jung-Mo Ahn, Salvatore Di Maro, 2009, Advances in experimental medicine and biology.

Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step.

E. Novellino, F. Da Settimo, C. La Motta, 2012, European journal of medicinal chemistry.

The bright side of chemistry: Exploring synthetic peptide‐based anticancer vaccines

Alessandra Del Bene, Vincenzo Mazzarella, Salvatore Di Maro, 2024, Journal of peptide science : an official publication of the European Peptide Society.

Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites.

F. Merlino, R. Russo, R. Benedetti, 2024, European journal of medicinal chemistry.