Jim Warwicker

发表

A protein chimera strategy supports production of a model “difficult‐to‐express” recombinant target

Hirra Hussain, David I Fisher, Robert G Roth, 2018, FEBS letters.

SitesIdentify: a protein functional site prediction tool

Salim Bougouffa, Jim Warwicker, Andrew J. Doig, 2009, BMC Bioinformatics.

Charge and hydrophobicity are key features in sequence-trained machine learning models for predicting the biophysical properties of clinical-stage antibodies

Jim Warwicker, Max Hebditch, J. Warwicker, 2019, bioRxiv.

Protein-sol pKa: prediction of electrostatic frustration, with application to coronaviruses

Jim Warwicker, Max Hebditch, 2020, Bioinform..

Charge and hydrophobicity are key features in sequence-trained machine learning models for predicting the biophysical properties of clinical-stage antibodies

Jim Warwicker, Max Hebditch, 2019, PeerJ.

Energetic Fingerprinting of Ligand Binding to Paralogous Proteins: The Case of the Apoptotic Pathway

Jim Warwicker, Roland G Huber, Peter J Bond, 2018, J. Chem. Inf. Model..

Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfaces

Salim Bougouffa, Jim Warwicker, S. Bougouffa, 2008, BMC Bioinformatics.

A model for pH coupling of the SARS-CoV-2 spike protein open/closed equilibrium

Jim Warwicker, 2021, Briefings Bioinform..

Effect of phosphorylation on alpha-helix stability as a function of position.

Jim Warwicker, Charles D Andrew, Gareth R Jones, 2002, Biochemistry.

Lysine and Arginine Content of Proteins: Computational Analysis Suggests a New Tool for Solubility Design

Jim Warwicker, Spyros Charonis, J. Warwicker, 2013, Molecular pharmaceutics.

Prediction of pKa and redox properties in the thioredoxin superfamily.

Jim Warwicker, J. Warwicker, Efrosini Moutevelis, 2004, Protein science : a publication of the Protein Society.

Subcellular pH and predicted pH‐dependent features of proteins

Jim Warwicker, Josip Lovrić, Pedro Chan, 2006, Proteomics.

pKa predictions with a coupled finite difference Poisson–Boltzmann and Debye–Hückel method

Jim Warwicker, J. Warwicker, 2011, Proteins.

Side‐chain conformational entropy at protein–protein interfaces

Christian Cole, Jim Warwicker, J. Warwicker, 2002, Protein science : a publication of the Protein Society.

PROGRESS IN THE PREDICTION OF pK a VALUES IN PROTEINS

Nathan A. Baker, Emil Alexov, Damien Farrell, 2011 .

Soluble expression of proteins correlates with a lack of positively-charged surface

Jim Warwicker, Pedro Chan, J. Warwicker, 2013, Scientific Reports.

The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment

Shahid Uddin, Alain Pluen, Jim Warwicker, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Models for Antibody Behavior in Hydrophobic Interaction Chromatography and in Self-Association.

Jim Warwicker, Max Hebditch, J. Warwicker, 2019, Journal of pharmaceutical sciences.

Stability and solubility of proteins from extremophiles.

Jim Warwicker, R. Greaves, J. Warwicker, 2009, Biochemical and biophysical research communications.

Improved pKa calculations through flexibility based sampling of a water‐dominated interaction scheme

Jim Warwicker, J. Warwicker, 2004, Protein science : a publication of the Protein Society.

Charge environments around phosphorylation sites in proteins

Jim Warwicker, J. Warwicker, R. Saunders, 2008, BMC Structural Biology.

TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid*

Jim Warwicker, Michael J O Wakelam, J. Warwicker, 2002, The Journal of Biological Chemistry.

Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”

Birgit Eisenhaber, Frank Eisenhaber, Jim Warwicker, 2017, BMC Biology.