Christos Sotiriou

发表

Model selection in meta-analytical framework for prototype-based clustering

Benjamin Haibe-Kains, Gianluca Bontempi, Christine Desmedt, 2007 .

Computational Intelligence in Clinical Oncology: Lessons Learned from an Analysis of a Clinical Study

Benjamin Haibe-Kains, Gianluca Bontempi, Christine Desmedt, 2008, Computational Intelligence in Biomedicine and Bioinformatics.

Multiple-input multiple-output causal strategies for gene selection

Benjamin Haibe-Kains, John Quackenbush, Gianluca Bontempi, 2011, BMC Bioinformatics.

2161 POSTER INTEGRATE: Driving Excellence in Integrative Cancer Research Through Innovative Biomedical Infrastructures

Christine Desmedt, Christos Sotiriou, Anca I. D. Bucur, 2011 .

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

Søren Brunak, Benjamin Haibe-Kains, Zoltan Szallasi, 2011, BMC Bioinformatics.

A comparative study of survival models for breast cancer prognostication based on microarray data: does a single gene beat them all?

Benjamin Haibe-Kains, Gianluca Bontempi, Christine Desmedt, 2008, Bioinform..

NIHMS662581-supplement-Supplementary data

Pardeep Kumar, Elizabeth Anderson, Jon W. Teague, 2016 .

Microarray Data Generation and Analysis : Class Discovery and Class Prediction from Human Cancer Microarray Datasets

Benjamin Haibe-Kains, Gianluca Bontempi, Christos Sotiriou, 2006 .

Low Power Monolithic 3D IC Design of Asynchronous AES Core

Sung Kyu Lim, Christos Sotiriou, Neela Lohith Penmetsa, 2015, 2015 21st IEEE International Symposium on Asynchronous Circuits and Systems.

Network science in clinical trials: A patient-centered approach.

Benjamin Haibe-Kains, Christos Sotiriou, Venkata S K Manem, 2017, Seminars in cancer biology.

R-Abax: A Radiation Hardening Legalisation Algorithm Satisfying TMR Spacing Constraints

Oliver Schrape, Milos Krstic, Anselm Breitenreiter, 2020, 2020 IEEE Computer Society Annual Symposium on VLSI (ISVLSI).

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

Carme Camps, Jiannis Ragoussis, Francesca M. Buffa, 2008, Clinical Cancer Research.

The use of gene-expression profiling to better understand the clinical heterogeneity of estrogen receptor positive breast cancers and tamoxifen response.

Christos Sotiriou, Sherene Loi, C. Sotiriou, 2007, Critical reviews in oncology/hematology.

Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations

Lajos Pusztai, Diether Lambrechts, Christine Desmedt, 2017, Nature Communications.

Evaluation of biological pathways involved in chemotherapy response in breast cancer

Jing Wang, Lajos Pusztai, Christos Sotiriou, 2008, Breast Cancer Research.

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials.

Benjamin Haibe-Kains, Zoltan Szallasi, Charles Swanton, 2010, The Lancet. Oncology.

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Carsten Denkert, Stefan Michiels, Christos Sotiriou, 2015, JAMA oncology.

Processed pseudogenes acquired somatically during cancer development

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Nature Communications.

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

David Gacquer, Peter J. Campbell, Christine Desmedt, 2015, bioRxiv.

CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib

Isabelle Salmon, Sylvain Brohée, Christos Sotiriou, 2017, EMBO molecular medicine.

Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study.

Lajos Pusztai, Christos Sotiriou, Kenneth R Hess, 2007, The Lancet. Oncology.

PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer

John M. S. Bartlett, Stefan Michiels, Christos Sotiriou, 2013, PloS one.

Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

Stefan Michiels, Benjamin Haibe-Kains, Christine Desmedt, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (her2) therapy in primary HER2-overexpressing breast cancer.

Carsten Denkert, Peter A Fasching, Andreas Schneeweiss, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers.

Heikki Joensuu, Carsten Denkert, Damien Drubay, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

DNA methylation–based immune response signature improves patient diagnosis in multiple cancers

Gianluca Bontempi, Matthieu Defrance, Christine Desmedt, 2017, The Journal of clinical investigation.

Molecular Pathways Molecular Pathways : Involvement of ImmunePathways in the Therapeutic Response and Outcome in Breast Cancer

Carsten Denkert, Giuseppe Curigliano, Christos Sotiriou, 2012 .

Genomic index of sensitivity to endocrine therapy for breast cancer.

Peter Regitnig, Christos Hatzis, Lajos Pusztai, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Molecular Profiling: Moving Away from Tumor Philately

Jorge S. Reis-Filho, Christos Sotiriou, Debora Fumagalli, 2010, Science Translational Medicine.

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

Carsten Denkert, Christos Sotiriou, Mark J. Smyth, 2016, Nature Reviews Clinical Oncology.

Discrimination between healthy and tumor tissues on formalin-fixed paraffin-embedded breast cancer samples using IR imaging

Christine Desmedt, Christos Sotiriou, Erik Goormaghtigh, 2010 .

Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues

Benjamin Haibe-Kains, Christine Desmedt, Christos Sotiriou, 2009, BMC Genomics.

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Andrew Menzies, Keiran Raine, Young Seok Ju, 2015, Nature Medicine.

MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.

Christos Sotiriou, Sarah Dedeurwaerder, Emilie Calonne, 2016, Molecular bioSystems.

Bringing molecular prognosis and prediction to the clinic.

Christos Sotiriou, Mariantonietta Colozza, Denis Larsimont, 2005, Clinical breast cancer.

Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers.

Carsten Denkert, Stephan Wienert, Frederick Klauschen, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.

Christos Sotiriou, Edison T Liu, C. Sotiriou, 2002, Journal of the National Cancer Institute.

Dissecting the heterogeneity of triple-negative breast cancer.

Paul Ellis, Christos Sotiriou, Sherene Loi, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Luminal B breast cancer: molecular characterization, clinical management, and future perspectives.

Christos Sotiriou, Debora Fumagalli, C. Sotiriou, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Multi-centre independent validation of a gene prognostic signature for patients with node-negative breast cancer (BC) - final results

Marc Buyse, Mauro Delorenzi, Christos Sotiriou, 2005 .

The 2019 World Health Organization classification of tumours of the breast

Christos Sotiriou, Hironobu Sasano, Puay Hoon Tan, 2020, Histopathology.

Transforming genomic grade index (GGI) into a user-friendly qRT-PCR tool which will assist clinicians and patients in optimizing treatment of early breast cancer (BC)

Gianluca Bontempi, Marc Buyse, Benjamin Haibe-Kains, 2007 .

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Bin Tean Teh, Andrew Menzies, Keiran Raine, 2014, eLife.

On-treatment changes in tumor-infiltrating lymphocytes (TIL) during neoadjuvant HER2 therapy (NAT) and clinical outcome.

Lajos Pusztai, Christos Sotiriou, Stephen B. Fox, 2019, Journal of Clinical Oncology.

DNA methylation profiling reveals a predominant immune component in breast cancers

Benjamin Haibe-Kains, Stefan Michiels, Matthieu Defrance, 2011, EMBO molecular medicine.

Gene Expression Profiles Associated with Response to Chemotherapy in Epithelial Ovarian Cancers

Javed Khan, Michael J. Birrer, Christos Sotiriou, 2005, Clinical Cancer Research.

Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98.

Stefan Michiels, Christos Sotiriou, Martine J Piccart, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

HER-2 as a Target for Breast Cancer Therapy

Christine Desmedt, Christos Sotiriou, C. Sotiriou, 2009, Clinical Cancer Research.

Correction to: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (Nature, (2016), 534, 7605, (47-54), 10.1038/nature17676)

Ville Mustonen, Sung-Min Ahn, Stefania Tommasi, 2019 .

Breast cancer gene expression profiling: clinical trial and practice implications.

Christine Desmedt, Christos Sotiriou, Fatima Cardoso, 2005, Pharmacogenomics.

Biological mechanisms that trigger breast cancer (BC) tumor progression are molecular subtype dependent

Gianluca Bontempi, Marc Buyse, Mauro Delorenzi, 2007 .

Gene-expression signatures in breast cancer.

Lajos Pusztai, Christos Sotiriou, C. Sotiriou, 2009, The New England journal of medicine.

CD4⁺ follicular helper T cell infiltration predicts breast cancer survival.

Benjamin Haibe-Kains, Stefan Michiels, Christine Desmedt, 2013, The Journal of clinical investigation.

Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group.

Jack Cuzick, Lisa McShane, Christos Sotiriou, 2011, Journal of the National Cancer Institute.

Infrared imaging in breast cancer: automated tissue component recognition and spectral characterization of breast cancer cells as well as the tumor microenvironment.

Christine Desmedt, Christos Sotiriou, Erik Goormaghtigh, 2014, The Analyst.

Defining the galaxy of gene expression in breast cancer

Christos Sotiriou, Edison T Liu, 2002, Breast Cancer Research.

Circulating tumor cells and emerging blood biomarkers in breast cancer

Christos Sotiriou, C. Sotiriou, C. Criscitiello, 2010, Current opinion in oncology.

The Gene expression Grade Index: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1–98 trial

Patrick Neven, Benjamin Haibe-Kains, Christine Desmedt, 2009, BMC Medical Genomics.

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

Gianluca Bontempi, Marc Buyse, Mauro Delorenzi, 2008, Clinical Cancer Research.

Comprehensive molecular analysis of several prognostic signatures using molecular indices related to hallmarks of breast cancer: proliferation index appears to be the most significant component of all signatures

Gianluca Bontempi, Marc Buyse, Mauro Delorenzi, 2006 .

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Science.

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothe

Carsten Denkert, Fred Hirsch, Benjamin Solomon, 2017, Advances in anatomic pathology.

Proliferation: the Most Prominent Predictor of Clinical Outcome in Breast Cancer

Christine Desmedt, Christos Sotiriou, C. Sotiriou, 2006, Cell cycle.

A fuzzy gene expression-based computational approach improves breast cancer prognostication

Benjamin Haibe-Kains, Gianluca Bontempi, Christine Desmedt, 2010, Genome Biology.

Comparison of prognostic gene expression signatures for breast cancer

Gianluca Bontempi, Marc Buyse, Benjamin Haibe-Kains, 2008, BMC Genomics.

Biology of breast cancer during pregnancy using genomic profiling.

Diether Lambrechts, Sylvain Brohée, Christine Desmedt, 2014, Endocrine-related cancer.

PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor–positive breast cancer

Paul Ellis, Terence P. Speed, Benjamin Haibe-Kains, 2010, Proceedings of the National Academy of Sciences.

CD 4 + follicular helper T cell infiltration predicts breast cancer survival

Benjamin Haibe-Kains, Stefan Michiels, Christine Desmedt, 2013 .

No significant viral transcription detected in whole breast cancer transcriptomes

David Gacquer, Christos Sotiriou, Debora Fumagalli, 2015, BMC Cancer.

Liquid biopsy-based clinical research in early breast cancer: The EORTC 90091-10093 Treat CTC trial.

Brigitte Rack, Christos Sotiriou, Sabine Riethdorf, 2016, European journal of cancer.

Multifactorial approach to predicting resistance to anthracyclines.

Yuan Qi, Gianluca Bontempi, Marc Buyse, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

Zoltan Szallasi, Lihua Zou, Yang Li, 2010, Nature Medicine.