J. L. DiCapua

Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folat

Wei Zhu, D. Priest, M. Bunni, 2002, Journal of experimental therapeutics & oncology.