W. Wigley

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Restriction fragment length polymorphism (RFLP) analysis provides evidence for a high degree of homology of mitochondrial DNAs from rat hepatomasVersus normal rat livers

R. A. Nakashima, W. C. Wigley, Xin Li, 1992, Biochemical Genetics.

Restriction fragment length polymorphism (RFLP) analysis provides evidence for a high degree of homology of mitochondrial DNAs from rat hepatomasVersus normal rat livers

R. A. Nakashima, W. C. Wigley, Xin Li, 1992, Biochemical Genetics.

Protein solubility and folding monitored in vivo by structural complementation of a genetic marker protein

John F. Hunt, Nathan M. Smith, Philip J. Thomas, 2001, Nature Biotechnology.

Activity and Regulation of the Centrosome-associated Proteasome*

P. Thomas, G. Demartino, W. C. Wigley, 2000, The Journal of Biological Chemistry.

Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function

Takafumi Suzuki, Masayuki Yamamoto, H. Nagasu, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

CFTR degradation and aggregation.

P. Thomas, M. J. Corboy, W. Wigley, 2002, Methods in molecular medicine.

Interferon gamma regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies.

P. Thomas, G. Demartino, W. C. Wigley, 2001, Journal of cell science.

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

D. Ferguson, Xin J. Zhou, Christopher Y. Lu, 2011, American journal of physiology. Renal physiology.

Regulation of Cl−/ HCO3 −Exchange by Cystic Fibrosis Transmembrane Conductance Regulator Expressed in NIH 3T3 and HEK 293 Cells*

M. G. Lee, Min Goo Lee, S. Muallem, 1999, The Journal of Biological Chemistry.

The Molecular Genetics of Steroid 5α-Reductases

D. Russell, R. Silver, D. M. Berman, 1994 .

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.

I. Dulubova, V. Stoll, K. Swinger, 2016, Biochimica et biophysica acta.

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy

M. Walker, S. Kovac, T. Shekh-Ahmad, 2019, Redox biology.

A Screen to Identify Cellular Modulators of Soluble Levels of an Amyotrophic Lateral Sclerosis (ALS)–Causing Mutant SOD1

P. Thomas, G. Miller, Balajee R. Somalinga, 2011, Journal of biomolecular screening.

Assessment of protein folding/solubility in live cells.

J. Hunt, P. Thomas, Rhesa D. Stidham, 2003, Methods in molecular biology.

Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.

J. Bliska, A. Dinkova-Kostova, T. Honda, 2012, Journal of medicinal chemistry.

Natural mutagenesis study of the human steroid 5α-reductase 2 isozyme

D. Russell, M. New, I. Mowszowicz, 1994 .

Natural mutagenesis study of the human steroid 5 alpha-reductase 2 isozyme.

D. Russell, J. Wilson, M. New, 1994, Biochemistry.

Aggresome formation.

P. Thomas, M. J. Corboy, W. Wigley, 2005, Methods in molecular biology.

The molecular genetics of steroid 5 alpha-reductases.

D. Russell, R. Silver, D. M. Berman, 1994, Recent progress in hormone research.

Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405

D. Ferguson, W. C. Wigley, B. Probst, 2015, PloS one.

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity

I. Dulubova, D. Ferguson, B. Probst, 2015, PloS one.

A Conserved GXXXG Motif in APH-1 Is Critical for Assembly and Activity of the γ-Secretase Complex*

P. Thomas, Sheu-Fen Lee, J. Lundkvist, 2004, Journal of Biological Chemistry.

Nrf2 regulates glucose uptake and metabolism in neurons and astrocytes

M. Duchen, A. Dinkova-Kostova, T. Blacker, 2023, Redox biology.

Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity.

K. Ward, S. Sonis, C. Meyer, 2013, American journal of physiology. Renal physiology.

Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD

M. Jadoul, G. Chertow, D. Ferguson, 2020, Clinical and translational science.

The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

D. Ferguson, M. Ding, R. Ma, 2012, Kidney international.

Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS

P. Giunti, Suran Nethisinghe, R. Abeti, 2021, International journal of molecular sciences.

NRF2 as an Emerging Therapeutic Target

T. Kensler, A. Dinkova-Kostova, K. Liby, 2017, Oxidative medicine and cellular longevity.

Bmc Cell Biology Hook2 Contributes to Aggresome Formation

H. Krämer, P. Thomas, W. C. Wigley, 2007 .

A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt.

I. Dulubova, D. Ferguson, Liping Liu, 2020, Bioorganic & medicinal chemistry letters.

A protein sequence that can encode native structure by disfavoring alternate conformations

Min Goo Lee, J. Rizo, J. Hunt, 2002, Nature Structural Biology.

Detection of a progression‐linked DNA restriction fragment in rat hepatoma cells probed with a hexokinase CDNA

R. A. Nakashima, W. C. Wigley, G. E. Corson, 1993, International journal of cancer.

205 Discovery and Development of Bardoxolone Methyl, an Antioxidant Inflammation Modulator (AIM) Targeting the KEAP1-NRF2 Pathway

M. Sporn, D. Ferguson, K. Liby, 2011 .

Hook2 contributes to aggresome formation

H. Krämer, P. Thomas, G. Szebenyi, 2007, BMC Cell Biology.

The glacial geology of the Copper Basin, Custer County, Idaho: A morphologic and pedogenic approach.

W. C. Wigley, W. Wigley, 1976 .