Arthur Weiss

发表

Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT

J. Kuriyan, Neel H. Shah, A. Weiss, 2018, Nature Immunology.

A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function

A. Marson, B. Evavold, M. Revelo, 2023, Nature Immunology.

The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence.

J. Engel, P. Balachandran, L. Dragone, 2007, The Journal of clinical investigation.

Phee, H. , Abraham, R.T. & Weiss, A. Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. Nat. Immunol. 6, 608-617

R. Abraham, H. Phee, A. Weiss, 2005 .

The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P2 replenishment in response to TCR signaling during T cell development and survival

J. Liou, K. Shrinivas, Byron B. Au-Yeung, 2022, Nature Immunology.

The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein.

Arthur Weiss, Andrew C. Chan, A. Chan, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

A. Weiss, G. Koretzky, T. Kadlecek, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Bacterial Virulence Proteins as Tools to Rewire Kinase Pathways in Yeast and Immune Cells

Wendell A. Lim, Sergio G. Peisajovich, Wilson W. Wong, 2012, Nature.

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases.

A. Weiss, A. Chan, B. Irving, 1994, Science.

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

M. Goldsmith, A. Weiss, Arthur Weiss, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65.

D. Yablonski, A. Weiss, Arthur Weiss, 2001, Advances in immunology.

Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells

K. Ansel, L. Samelson, A. Shaw, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C

L. Lanier, A. Weiss, A. Fry, 1996, The Journal of experimental medicine.

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation.

J. Wu, A. Weiss, G. Koretzky, 1996, Immunity.

Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus.

R. Majeti, A. Weiss, D. Ganem, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

A. Weiss, A. Chan, B. Irving, 1993, The Journal of experimental medicine.

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction.

A. Weiss, A. Chan, D. Desai, 1994, Annual review of immunology.

The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation

A. Weiss, D. Straus, Arthur Weiss, 1993, The Journal of experimental medicine.

Signal transduction by the T cell antigen receptor.

A. Weiss, G. Koretzky, B. Irving, 1991, Seminars in immunology.

Multiple kinases mediate T-cell-receptor signaling.

A. Weiss, L. R. Howe, Arthur Weiss, 1995, Trends in biochemical sciences.

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.

A. Weiss, L. Turka, E. Clark, 1994, Journal of immunology.

CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.

A. Weiss, J. Bolen, M. Sieh, 1993, The EMBO journal.

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

A. Weiss, J. Picus, G. Koretzky, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes.

A. Weiss, N. V. van Oers, N. Oers, 1995, Seminars in immunology.

The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav.

A. Weiss, G. Packham, S. Katzav, 1994, The Journal of biological chemistry.

Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line.

A. Weiss, G. Koretzky, M. Kohmetscher, 1992, Journal of immunology.

The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit

A. Weiss, H. von Boehmer, N. V. van Oers, 1995, The Journal of experimental medicine.

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling

A. Weiss, M. Mollenauer, D. Qian, 1996, The Journal of experimental medicine.

Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene

N. Taylor, K. Weinberg, E. Gelfand, 1996, The Journal of experimental medicine.