Michal Bista

Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

Paul Hemsley, Joseph Shaw, Ian Dale, 2018, SLAS discovery : advancing life sciences R & D.

Domain–domain interactions in full-length p53 and a specific DNA complex probed by methyl NMR spectroscopy

Michal Bista, A. Fersht, S. Freund, 2012, Proceedings of the National Academy of Sciences.

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Michael A. Dyer, Artur Pirog, Michal Bista, 2012, PloS one.

Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists

Grzegorz M. Popowicz, Alexander Dömling, Carlos J. Camacho, 2012, PloS one.

Robust generation of lead compounds for protein-protein interactions by computational and MCR chemistry: p53/Hdm2 antagonists.

Alexander Dömling, Michal Bista, Stuti Srivastava, 2010, Angewandte Chemie.

Transient protein states in designing inhibitors of the MDM2-p53 interaction.

Alexander Dömling, Michal Bista, Kareem Khoury, 2013, Structure.

Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival.

Graeme Walker, Lisa Wissler, Jon Read, 2016, Journal of medicinal chemistry.

Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease

Michal Bista, David Rueda, Jon A Read, 2017, Nature Communications.