Stefan Vasile

发表

Scheme 3, General synthetic strategy for analogs of ML261

Jiwen Zou, Santhi Ganji, Ian Pass, 2014 .

Table 3, Probe and Analog Submissions to MLSMR (Evotec) for P. falciparum G-6PDH antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6E, LCMS purity data at 214 nm for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); LCMS retention time: 3.125 min; purity at 214 nm = 97.5%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Challenges of developing resonant cavity photon-counting detectors at 1064 nm

Stefan Vasile, M. Selim Ünlü, Jerold Lipson, 2010, LASE.

Figure 3, Profiling of the 21 most active VHR screening hits at 20 µM against VHR (AID-2074) & HePTP (AID-2082)

Stefan Vasile, Ying Su, Thomas D.Y. Chung, 2010 .

Figure 9, Structure of confirmed most attractive screening hits

Jiwen Zou, Santhi Ganji, Ian Pass, 2014 .

CERTIFICATION - The final and critical stage of every civil or military aviation program

Stefan Vasile, Tataru Simion, Olivotto Constantin, 2012 .

ASIC Readout Circuit Architecture for Large Geiger Photodiode Arrays

Stefan Vasile, Jerold Lipson, 2012 .

Figure A6F, HRMS data for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); HRMS m/z calculated for C16H17ClN3O6S [M + H+]: 414.0521, found 414.0522

Stefan Vasile, Eigo Suyama, Anthony B. Pinkerton, 2013 .

Scheme 1, Synthesis of ML377

Susanne Heynen-Genel, Stefan Vasile, Eigo Suyama, 2015 .

Scheme 1, Synthesis of ML304

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Scheme 1, Synthesis of ML261, conditions

Jiwen Zou, Santhi Ganji, Ian Pass, 2013 .

Scheme 1, Synthesis of ML260

Jiwen Zou, Santhi Ganji, Ian Pass, 2013 .

Table 4, Submission of Probe and 5 analogs to the MLSMR

Stefan Vasile, Thomas D.Y. Chung, Eduard Sergienko, 2010 .

[Table], EXPERIMENTAL RESULTS FOR SID 123083137 ON OTHER TARGETS

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Table 5, Potencies of key screening hit scaffolds

Jiwen Zou, Santhi Ganji, Ian Pass, 2014 .

Table 3, Probe and Analog Submissions to MLSMR (BioFocus DPI) for APJ Antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Scheme 1, Synthesis of ML276

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6C, LCMS purity data at 214 nm for ML291 1st batch (SID 123083137, CID 52940465); LCMS retention time: 3.074 min; purity at 214 nm = 95.4%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Single-photon imaging camera development for night vision

Stefan Vasile, Jurgen Michel, Jerold Lipson, 2010, Defense + Commercial Sensing.

Figure 3, Flowchart Summary of Screening Results

Stefan Vasile, Eigo Suyama, Ying Su, 2011 .

Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.

Stefan Vasile, Maurizio Pellecchia, Fabio Cerignoli, 2009, Journal of medicinal chemistry.

The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase alpha is mediated by hydrogen peroxide.

Stefan Vasile, Terence Hui, Gerald McMahon, 2004, Archives of biochemistry and biophysics.

Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2012, Journal of medicinal chemistry.

A Pharmacochaperone-Based High-Throughput Screening Assay for the Discovery of Chemical Probes of Orphan Receptors.

Stefan Vasile, Danielle McAnally, Haleli Sharir, 2018, Assay and drug development technologies.