Punit Upadhyaya

发表

Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology

N. Keen, P. Jeffrey, Jun Ma, 2022, Journal of medicinal chemistry.

Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptides.

Sarah R. Clippinger, Sarah R Clippinger, Punit Upadhyaya, 2015, Angewandte Chemie.

Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonist.

Punit Upadhyaya, Yusen Liu, D. Pei, 2013, Journal of the American Chemical Society.

BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™) induces tumor localized CD137 agonism

N. Keen, P. Jeffrey, S. Blakemore, 2021, Journal for ImmunoTherapy of Cancer.

Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist

Rachel L. Dods, N. Keen, Jun Ma, 2021, Journal for ImmunoTherapy of Cancer.

Discovery of a Bicyclic Peptidyl Pan-Ras Inhibitor.

Qi-En Wang, D. Pei, M. Buyanova, 2021, Journal of medicinal chemistry.

888 An integrative approach to optimize a synthetic EphA2/CD137 agonist: balancing potency, physiochemical properties, and pharmacokinetics to achieve robust anti-tumor activity

N. Keen, P. Jeffrey, J. Lahdenranta, 2021, Journal for ImmunoTherapy of Cancer.

Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides

D. Pei, Ziqing Qian, Thi B. Trinh, 2015, ACS combinatorial science.

Synthesis and screening of one-bead-one-compound cyclic peptide libraries.

D. Pei, P. Upadhyaya, Ziqing Qian, 2015, Methods in molecular biology.

Inhibition of Ras-Effector Interaction by Cyclic Peptides.

M. Villalona-Calero, R. Briesewitz, D. Pei, 2013, MedChemComm.

A AGONIST ™ ) INDUCES TUMOR LOCALIZED CD137 AGONISM AND MODULATION OF TUMOR IMMUNE MICROENVIRONMENT

K. Mcdonnell, P. Brandish, E. Repash, 2020 .

Direct Inhibitors of Ras-Effector Protein Interactions.

Punit Upadhyaya, D. Pei, Dehua Pei, 2016, Mini reviews in medicinal chemistry.

Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library.

D. Pei, Ziqing Qian, Punit Upadhyaya, 2014, Tetrahedron.

Abstract PO077: BT7480, a novel fully synthetic tumor-targeted immune cell agonist (TICA™) induces tumor localized 4-1BB agonism

N. Keen, Jun Ma, J. Lahdenranta, 2020 .